Zobrazeno 1 - 10
of 318
pro vyhledávání: '"Linda A. Parker"'
Publikováno v:
Psychoactives, Vol 3, Iss 2, Pp 184-193 (2024)
(1) Background: Intraperitoneal injections of the endogenous N-acyl amino acid N-Oleoyl alanine (OlAla) effectively reduces both the affective and somatic responses produced by opioid withdrawal in preclinical models. To increase the translational ap
Externí odkaz:
https://doaj.org/article/9a104bc3add74764b1d504012c051523
Autor:
Samantha M. Ayoub, Fabiana Piscitelli, Cristoforo Silvestri, Cheryl L. Limebeer, Erin M. Rock, Reem Smoum, Mathew Farag, Hannah de Almeida, Megan T. Sullivan, Sébastien Lacroix, Besma Boubertakh, Nayudu Nallabelli, Aron H Lichtman, Francesco Leri, Raphael Mechoulam, Vincenzo Di Marzo, Linda A. Parker
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Rationale: The endocannabinoidome mediators, N-Oleoylglycine (OlGly) and N-Oleoylalanine (OlAla), have been shown to reduce acute naloxone-precipitated morphine withdrawal affective and somatic responses.Objectives: To determine the role and mechanis
Externí odkaz:
https://doaj.org/article/ea5e6cc1a5dd458bad673a1b9b29595a
Autor:
Erin M. Rock, Cheryl L. Limebeer, Megan T. Sullivan, Marieka V. DeVuono, Aron H. Lichtman, Vincenzo Di Marzo, Raphael Mechoulam, Linda A. Parker
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 13 (2021)
The endogenous amide N-Oleoylglycine (OlGly) and its analog N-Oleoylalanine (OlAla), have been shown to interfere with the affective and somatic responses to acute naloxone-precipitated MWD in male rats. Here we evaluated the potential of a single do
Externí odkaz:
https://doaj.org/article/518b6faff5a9422b904f217ce7e61067
Autor:
Linda A. Parker
A review of the scientific evidence on the effects of cannabinoids on brain and behavioral functioning, with an emphasis on potential therapeutic use.The cannabis plant has been used for recreational and medicinal purposes for more than 4,000 years,
Autor:
Marieka V, DeVuono, Olivia, La Caprara, Gavin N, Petrie, Cheryl L, Limebeer, Erin M, Rock, Matthew N, Hill, Linda A, Parker
Publikováno v:
Cannabis Cannabinoid Res
Introduction: Cannabinoid hyperemesis syndrome (CHS) is characterized by intense nausea and vomiting brought on by the use of high-dose Δ(9)-tetrahydrocannabinol (THC), the main psychotropic compound in cannabis. Cannabidiol (CBD), a nonpsychotropic
Autor:
Matthew N. Hill, Cheryl L. Limebeer, Linda A. Parker, Marieka V. DeVuono, Gavin N. Petrie, Erin M. Rock, Olivia La Caprara
Publikováno v:
Cannabis and Cannabinoid Research. 7:58-64
Introduction: Cannabinoid hyperemesis syndrome (CHS) is characterized by intense nausea and vomiting brought on by the use of high-dose Δ9-tetrahydrocannabinol (THC), the main psychotropic compound...
Publikováno v:
Psychopharmacology. 239:377-383
RATIONALE The fatty acid amide oleoyl glycine (OlGly) and its more stable methylated form oleoyl alanine (OlAla) reduce naloxone-precipitated morphine withdrawal (MWD)-induced conditioned gaping (nausea) responses in rats. In addition, OlGly has been
Autor:
Fátima Duarte-Aké, Linda A. Parker, Rosa Us-Camas, José Carlos Pastrana-Trejo, Roger G. Pertwee, Clelia De-la-Peña, Eric Murillo-Rodríguez
Publikováno v:
Central Nervous System Agents in Medicinal Chemistry. 21:142-147
Background: Cannabidiol (CBD), a non-psychotropic constituent of Cannabis sativa, has shown therapeutic promises by modulating several pathological conditions, including pain, epilepsy autism, among others. However, the molecular mechanism of action
Publikováno v:
Cannabis and cannabinoid research.
A comprehensive review of the scientific literature on the possible benefits of CBD, describing findings from both preclinical and human clinical studies. CBD (cannabidiol), a nonintoxicating compound derived from the cannabis plant, can be found in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78b4b1c1a5f020fed7a82da275273754
https://doi.org/10.7551/mitpress/13686.001.0001
https://doi.org/10.7551/mitpress/13686.001.0001