Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Linda A. Heffernan-Stroud"'
Publikováno v:
JAAD Case Reports
Bowel-associated dermatosis-arthritis syndrome (BADAS) is a recurrent and episodic neutrophilic dermatosis characterized by erythematous macules, which quickly evolve into papules and vesiculopustules on the trunk and upper extremities.1, 2 Originall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164a56b05fa3d730f872172f49aea2a5
https://doi.org/10.1016/j.jdcr.2016.05.012
https://doi.org/10.1016/j.jdcr.2016.05.012
Autor:
Yusuf A. Hannun, Kristi L. Helke, Linda A. Heffernan-Stroud, Lina M. Obeid, Russell W. Jenkins, Anna-Maria A. De Costa
Publikováno v:
Oncogene
p53 is a crucial tumor suppressor that is mutated or deleted in a majority of cancers. Exactly how p53 prevents tumor progression has proved elusive for many years; however, this information is crucial to define targets for chemotherapeutic developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d6aeaf3c3cef5c8a08ed7829d25fb61
http://europepmc.org/articles/PMC3278571
http://europepmc.org/articles/PMC3278571
Autor:
Ashley J. Snider, Christopher R. Gault, Fabio Simbari, Yusuf A. Hannun, Linda A. Heffernan-Stroud, Russell W. Jenkins, Daniel Canals, Patrick Roddy, Bill X. Wu, Lina M. Obeid, Kazuyuki Kitatani, Christopher J. Clarke
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Acid sphingomyelinase (aSMase) generates the bioactive lipid ceramide (Cer) from hydrolysis of sphingomyelin (SM). However, its precise roles in regulating specific sphingolipid-mediated biological processes remain ill defined. Interestingly, the aSM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d94868ddbe5ecd9b1dc414addcc58cd
https://doi.org/10.1074/jbc.m110.163378
https://doi.org/10.1074/jbc.m110.163378
Publikováno v:
Advances in cancer research. 117
The role of sphingolipids as bioactive signaling molecules that can regulate cell fate decisions puts them at center stage for cancer treatment and prevention. While ceramide and sphingosine have been established as antigrowth molecules, sphingosine-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada2de206c672bc32cb99cd5cdc6549f
https://pubmed.ncbi.nlm.nih.gov/23290781
https://pubmed.ncbi.nlm.nih.gov/23290781
Both the sphingolipid and p53 pathways are important regulators- and apparent collaborators-of cell-fate decisions. Whereas some investigations have suggested that ceramide and more complex sphingolipids function upstream of p53 or in a p53-independe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5fc53e477a4b9b33df5c70085ccbdd3
https://europepmc.org/articles/PMC3078951/
https://europepmc.org/articles/PMC3078951/
