Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Linda A. Guernsey"'
Autor:
Eric R. Secor, Roger S. Thrall, Linda A. Guernsey, Ektor Rafti, Sonali J. Bracken, Biree Andemariam, Adam P. Matson, Steven M. Szczepanek
Publikováno v:
Pediatric research
Background Children with sickle cell disease (SCD) are susceptible to recurrent infections, which are often life threatening and necessitate frequent vaccinations. Given the altered baseline immunity and proinflammatory state associated with SCD, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::235b92b60dba0177f6ea45be78fb9321
http://europepmc.org/articles/PMC4487511
http://europepmc.org/articles/PMC4487511
Autor:
Craig M. Schramm, Roger S. Thrall, Linda A. Guernsey, Jeffrey Rovatti, Carol A. Wu, Eric R. Secor, Jennifer Ser-Dolansky, Clinton B. Mathias, Hector L. Aguila, Sallie S. Schneider, Stephanie H. Polukort
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 47(5)
Background Interleukin-15 is a pleiotropic cytokine that is critical for the development and survival of multiple hematopoietic lineages. Mice lacking IL-15 have selective defects in populations of several pro-allergic immune cells including natural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb4abade42cf656949a66976e10c1913
https://pubmed.ncbi.nlm.nih.gov/28093832
https://pubmed.ncbi.nlm.nih.gov/28093832
Autor:
Craig M. Schramm, Prabitha Natarajan, Jeffrey T. McNamara, Anurag Singh, Roger S. Thrall, Linda A. Guernsey, Eric R. Secor
Publikováno v:
Mucosal immunology
In a biphasic, ovalbumin (OVA)-induced murine asthma model where allergic airway disease is followed by resolution and the development of local inhalational tolerance (LIT), transforming growth factor (TGF)-β-expressing CD5(+) B cells were selective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f0d929d709391fba3ff291cbdeb087b
https://doi.org/10.1038/mi.2012.42
https://doi.org/10.1038/mi.2012.42
Autor:
Jeff McNamara, Roger S. Thrall, Linda A. Guernsey, Eric R. Secor, Anurag Singh, Lijun Zhan, Nilanjana Maulik
Publikováno v:
International Immunopharmacology. 9:340-346
Bromelain (Br), an extract from pineapple stem with cysteine protease activity, exerts anti-inflammatory effects in a number of inflammatory models. We have previously shown that Br treatment decreased activated CD4(+) T cells and has a therapeutic r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e05a92b40cb233c8c8f4ebbdfbbc037
https://doi.org/10.1016/j.intimp.2008.12.012
https://doi.org/10.1016/j.intimp.2008.12.012
Autor:
Biree Andemariam, Roger S. Thrall, Linda A. Guernsey, Anurag Singh, Alexander J. Adami, Eric R. Secor, Jeffrey T. McNamara
Comorbid asthma in sickle cell disease (SCD) confers higher rates of vaso-occlusive pain and mortality, yet the physiological link between these two distinct diseases remains puzzling. We used a mouse model of SCD to study pulmonary immunology and ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c77c2fac568dbccddf6a8b414f571f
https://europepmc.org/articles/PMC4537824/
https://europepmc.org/articles/PMC4537824/
Publikováno v:
The American Journal of Pathology. 164:1849-1856
The electrophysiological properties of cultured tracheal cells (CTCs) were examined in a murine (C57BL/6J), ovalbumin (OVA)-induced model of allergic airway disease (AAD) at early (3-day OVA-aerosol) and peak (10-day OVA-aerosol) periods of inflammat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0338b0240c9ad2470800a77b5e8efb33
https://doi.org/10.1016/s0002-9440(10)63743-1
https://doi.org/10.1016/s0002-9440(10)63743-1
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1190
B cells have long been known to participate in both innate and adaptive immune responses by contributing to antigen presentation and by producing antigen-specific antibodies. Recent evidence shows that certain B-cell subsets can also inhibit T-cell i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::32eb9f78fcd95316d988b3e4e240501b
https://pubmed.ncbi.nlm.nih.gov/25015283
https://pubmed.ncbi.nlm.nih.gov/25015283
Publikováno v:
Lung. 176:393-401
Tannin, isolated from cotton bracts and implicated in the pathogenesis of byssinosis, inhibits isoproterenol and forskolin-stimulated cAMP release from airway cells in part by decreasing cell surface beta-adrenergic receptor number and uncoupling the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10533a8ff4b6ed9c63c32394460e5bb3
https://doi.org/10.1007/pl00007621
https://doi.org/10.1007/pl00007621
Publikováno v:
Methods in Molecular Biology ISBN: 9781493911608
B cells have long been known to participate in both innate and adaptive immune responses by contributing to antigen presentation and by producing antigen-specific antibodies. Recent evidence shows that certain B-cell subsets can also inhibit T-cell i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acba8544f1219cdc21d8440e4f6d9074
https://doi.org/10.1007/978-1-4939-1161-5_15
https://doi.org/10.1007/978-1-4939-1161-5_15
Autor:
Claire Brammer, Hector L. Aguila, Clinton B. Mathias, David J. Zammit, Roger S. Thrall, Linda A. Guernsey, Carol A. Wu
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 44(4)
Natural Killer (NK) cells have been implicated in the development of allergic airway inflammation. However, the in vivo role of NK cells has not been firmly established due to the lack of animal models with selective deficiencies in NK cells.To deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a9f3280349bef7b835a6575b09d0dbd
https://pubmed.ncbi.nlm.nih.gov/24397722
https://pubmed.ncbi.nlm.nih.gov/24397722