Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Linda A. Chamberlin"'
Autor:
Daniel C. Lowes, Linda A. Chamberlin, Lisa N. Kretsge, Emma S. Holt, Atheir I. Abbas, Alan J. Park, Lyubov Yusufova, Zachary H. Bretton, Ayesha Firdous, Armen G. Enikolopov, Joshua A. Gordon, Alexander Z. Harris
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Acute stress transiently disrupts reward-seeking behaviour and repeated stress exposure produces lasting anhedonia-like behaviour in rodents. Here, the authors show that stress triggers GABAergic activity in the ventral tegmental area which blunts re
Externí odkaz:
https://doaj.org/article/00c4ef5a5a704504b5b5820961797043
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 10 (2018)
H-current, also known as hyperpolarization-activated current (Ih), is an inward current generated by the hyperpolarization-activated cyclic nucleotide-gated (HCN) cation channels. Ih plays an essential role in regulating neuronal properties, synaptic
Externí odkaz:
https://doaj.org/article/2aa907c7278e41d69e2c1f1dbd4f497d
Autor:
Linda A. Chamberlin, Sha-Sha Yang, Erin P. McEachern, Joshua T. M. Lucas, Owen W. McLeod II, Claire A. Rolland, Nancy R. Mack, Brielle R. Ferguson, Wen-Jun Gao
Publikováno v:
Neuropsychopharmacology.
Publikováno v:
Molecular Psychiatry. 27:731-743
The neurobiology of schizophrenia involves multiple facets of pathophysiology, ranging from its genetic basis over changes in neurochemistry and neurophysiology, to the systemic level of neural circuits. Although the precise mechanisms associated wit
Autor:
Lyubov Yusufova, Ayesha Firdous, Daniel C. Lowes, Lisa N. Kretsge, Emma S Holt, Alexander Z. Harris, Alan J. Park, Linda A. Chamberlin, Joshua A. Gordon, Armen G. Enikolopov, Zachary H. Bretton, Atheir I. Abbas
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
Decreased pleasure-seeking (anhedonia) forms a core symptom of depression. Stressful experiences precipitate depression and disrupt reward-seeking, but it remains unclear how stress causes anhedonia. We recorded simultaneous neural activity across li
BACKGROUND: Schizophrenia (SZ) is most recognized by its psychotic symptoms, yet the cognitive deficits are more predictive of functional outcome and less responsive to treatment. The neuropathology underlying cognitive deficits remains elusive, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e84ee9f5127011704900be5cd49e9be9
https://europepmc.org/articles/PMC6455181/
https://europepmc.org/articles/PMC6455181/
Publikováno v:
Frontiers in Synaptic Neuroscience
Frontiers in Synaptic Neuroscience, Vol 10 (2018)
Frontiers in Synaptic Neuroscience, Vol 10 (2018)
H-current, also known as hyperpolarization-activated current (Ih), is an inward current generated by the hyperpolarization-activated cyclic nucleotide-gated (HCN) cation channels. Ih plays an essential role in regulating neuronal properties, synaptic
Publikováno v:
Biochemistry. 22:3072-3077
An abundant 20-kilodalton protein has been isolated from the cytosol fraction of rat ventral prostate by ammonium sulfate precipitation, DNA-cellulose chromatography, and gel filtration. The purified 20K protein is a glycoprotein, containing 11% hexo
Publikováno v:
Journal of steroid biochemistry. 24(4)
(1) Oxidation by molecular oxygen converted the 22Kdalton glycoprotein from rat ventral prostate into a 34K species and this reaction could be reversed by thiol reducing reagent. (2) Measurement of the level of the 22Kdalton glycoprotein in prostatic