Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Linda A Bradbury"'
Autor:
Emma L Duncan, Patrick Danoy, John P Kemp, Paul J Leo, Eugene McCloskey, Geoffrey C Nicholson, Richard Eastell, Richard L Prince, John A Eisman, Graeme Jones, Philip N Sambrook, Ian R Reid, Elaine M Dennison, John Wark, J Brent Richards, Andre G Uitterlinden, Tim D Spector, Chris Esapa, Roger D Cox, Steve D M Brown, Rajesh V Thakker, Kathryn A Addison, Linda A Bradbury, Jacqueline R Center, Cyrus Cooper, Catherine Cremin, Karol Estrada, Dieter Felsenberg, Claus-C Glüer, Johanna Hadler, Margaret J Henry, Albert Hofman, Mark A Kotowicz, Joanna Makovey, Sing C Nguyen, Tuan V Nguyen, Julie A Pasco, Karena Pryce, David M Reid, Fernando Rivadeneira, Christian Roux, Kari Stefansson, Unnur Styrkarsdottir, Gudmar Thorleifsson, Rumbidzai Tichawangana, David M Evans, Matthew A Brown
Publikováno v:
PLoS Genetics, Vol 7, Iss 4, p e1001372 (2011)
Osteoporotic fracture is a major cause of morbidity and mortality worldwide. Low bone mineral density (BMD) is a major predisposing factor to fracture and is known to be highly heritable. Site-, gender-, and age-specific genetic effects on BMD are th
Externí odkaz:
https://doaj.org/article/67487b75c7514774bb6c8bedffb4cbdc
Autor:
Patrick Danoy, Karena Pryce, Johanna Hadler, Linda A Bradbury, Claire Farrar, Jennifer Pointon, Australo-Anglo-American Spondyloarthritis Consortium, Michael Ward, Michael Weisman, John D Reveille, B Paul Wordsworth, Millicent A Stone, Spondyloarthritis Research Consortium of Canada, Walter P Maksymowych, Proton Rahman, Dafna Gladman, Robert D Inman, Matthew A Brown
Publikováno v:
PLoS Genetics, Vol 6, Iss 12, p e1001195 (2010)
Ankylosing spondylitis (AS) is a common inflammatory arthritic condition. Overt inflammatory bowel disease (IBD) occurs in about 10% of AS patients, and in addition 70% of AS cases may have subclinical terminal ileitis. Spondyloarthritis is also comm
Externí odkaz:
https://doaj.org/article/e7e7a644f80b4c5cb5acdf7d3d2ee2a0
Autor:
Linda A. Bradbury, Kim-Anh Lê Cao, Hendrik J. Nel, Tony J. Kenna, Aimee L. Hanson, Julie Phipps, Matthew A. Brown, Ranjeny Thomas
Publikováno v:
Arthritis & Rheumatology. 72:1289-1302
Ankylosing spondylitis (AS) is a common spondyloarthropathy primarily affecting the axial skeleton and strongly associated with HLA-B*27 carriage. Genetic evidence implicates both autoinflammatory processes and autoimmunity against a HLA-B*27-restric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce941c289caaf65cbab4286c2eb707f
https://doi.org/10.1002/art.41252
https://doi.org/10.1002/art.41252
Autor:
Kim-Anh Lê Cao, Kelly A. Hollis, Linda A. Bradbury, Benoit Gautier, Philip Robinson, Sateesh Shankaranarayana, Nivene Saad, Matthew A. Brown
Publikováno v:
The Journal of Rheumatology. 45:771-778
Objective.We tested the discriminatory capacity of diffusion-weighted magnetic resonance imaging (DWI) and its potential as an objective measure of treatment response to tumor necrosis factor inhibition in ankylosing spondylitis (AS).Methods.Three co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b0a05dd3efe559b1768b03f43906faf
https://doi.org/10.3899/jrheum.170312
https://doi.org/10.3899/jrheum.170312
Autor:
Patrick Danoy, Karena Pryce, Johanna Hadler, Linda A. Bradbury, Claire Farrar, Jennifer Pointon, Michael Ward, Michael Weisman, John D. Reveille, B. Paul Wordsworth, Millicent A. Stone, Walter P. Maksymowych, Proton Rahman, Dafna Gladman, Robert D. Inman, Matthew A. Brown
Publikováno v:
PLoS Genetics, Vol 7, Iss 2 (2011)
Externí odkaz:
https://doaj.org/article/f04c2a93758f4a2a8422411e04726c9d
Autor:
B. Paul Wordsworth, Philip Robinson, Mariapia A. Degli-Esposti, Nigil Haroon, Denis Wakefield, J J Pointon, Irene E. van der Horst-Bruinsma, Jessica Harris, Linda A. Bradbury, Lyndell L Lim, Matthew A. Brown, Proton Rahman, Alex W. Hewitt, David M. Evans, Lianne S. Gensler, Peter McCluskey, Walter P. Maksymowych, Peter Fleming, Jamie E Craig, Katie Cremin, Pamela Mukhopadhyay, Adrian Cortes, Michael H. Weisman, Joseph E. Powell, Robert D. Inman, John D. Reveille, Tammy M. Martin, Valentina Voigt, James T. Rosenbaum, Theodora A. M. Claushuis, Paul Leo
Publikováno v:
Arthritis & Rheumatology. 67:140-151
Free to read Objective To use high-density genotyping to investigate the genetic associations of acute anterior uveitis (AAU) in patients with and those without ankylosing spondylitis (AS). Methods We genotyped samples from 1,711 patients with AAU (e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3399c3db8a97f0a7ed834714b2c9b836
https://doi.org/10.1002/art.38873
https://doi.org/10.1002/art.38873
Autor:
Matthijs Janssen, Alexander So, Marilyn E. Merriman, Edward Roddy, Lisa K. Stamp, Philip Riches, Ruth Topless, Robert J. Walker, Twj Huizinga, Tony R. Merriman, Lab Joosten, Mariano Andrés, Murray Cadzow, J. de Zoysa, Matthew A. Brown, Geraldine M. McCarthy, Karel Pavelka, Christopher Hill, Fernando Perez-Ruiz, E. de Guzman, Donia Macartney-Coxson, Blanka Stiburkova, Nicola Dalbeth, Ken Yamamoto, Rosa J. Torres, Amanda Phipps-Green, T.L. Jansen, T R D J Radstake, Katie Cremin, Fina A S Kurreeman, S. Lester, Rinki Murphy, R. Stubbs, Linda A. Bradbury, Michael Doherty, E Stahl, Russell R C Buchanan, Abhishek Abhishek, A.-K. Tausche, Hirotaka Matsuo, Sally P.A. McCormick, Hyon K. Choi, Tanya J Flynn, Frédéric Lioté, Maureen Rischmueller, Juan G. Puig, Malcolm D. Smith
Publikováno v:
Poster Presentations.
Background Gout progresses through three stages: hyperuricemia, deposition of monosodium urate (MSU) crystals, and innate immune system response to MSU crystals. Genome wide association studies (GWAS) have provided insight into the molecular control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b7fc887f8950742f971d64b7120e1da
https://doi.org/10.1136/annrheumdis-2017-eular.5634
https://doi.org/10.1136/annrheumdis-2017-eular.5634
Autor:
Jonathan Ellis, X B Wang, Zhixiu Li, David J. Pennisi, K Hollis, Tony J. Kenna, Linda A. Bradbury, Matthew A. Brown, Xiaoxia Song, Jyotsna Batra
Publikováno v:
Genes and immunity. 18(3)
Tumor necrosis factor-α (TNF-α) inhibitors are highly effective in suppressing inflammation in ankylosing spondylitis (AS) patients, and operate by suppression of TFN-α and downstream immunological pathways. To determine the mechanisms of action o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3772c0240be6c58c00c3cfad46534c1e
https://pubmed.ncbi.nlm.nih.gov/28835680
https://pubmed.ncbi.nlm.nih.gov/28835680
Autor:
Max C. Lau, P-L. Low, Tony J. Kenna, Nitish Agrawal, Francesco Ciccia, Riccardo Alessandro, Patricia Keith, Mary-Ellen Costello, Matthew A. Brown, Giovanni Triolo, Gethin P. Thomas, Philip Robinson, Linda A. Bradbury
Publikováno v:
Genes & Immunity. 16:35-42
The mechanism by which human leukocyte antigen B27 (HLA-B27) contributes to ankylosing spondylitis (AS) remains unclear. Genetic studies demonstrate that association with and interaction between polymorphisms of endoplasmic reticulum aminopeptidase 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a63b0d0308fb86366fab392fde4c363d
https://doi.org/10.1038/gene.2014.62
https://doi.org/10.1038/gene.2014.62
Autor:
Linda A. Bradbury, Matthew A. Brown
Publikováno v:
The Medical journal of Australia. 206(5)
Free to read on journal website (may need to create free account first) There have been marked improvements in treatment options but none have yet been shown to induce remission The past decade has seen major advances in the diagnosis and management
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17f9fc31289843a2f2d8a8a712c105c3
https://pubmed.ncbi.nlm.nih.gov/28301782
https://pubmed.ncbi.nlm.nih.gov/28301782