Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Linda MacArthur"'
Publikováno v:
Expert Review of Neurotherapeutics. 13:685-693
Biomolecules in subnetworks are the focus of a new strategy to develop drugs that halt complex diseases. In this article, the authors use genome-wide association study and linkage data derived from Parkinson's disease studies to illustrate how algori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1364bd5a9da7227e5a6df4ac213896db
https://doi.org/10.1586/ern.13.59
https://doi.org/10.1586/ern.13.59
Publikováno v:
Journal of Neurochemistry. 115:625-634
The objective of this study was to identify and quantify the heteromeric neuronal nicotinic receptors (nAChRs) in the rat hippocampus. The density of nAChR subtypes was assessed by labeling them with [(3)H]epibatidine ([(3)H]EB) followed by immunopre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::264ddf5e51b6df265f5c1c9567a76bb6
https://doi.org/10.1111/j.1471-4159.2010.06967.x
https://doi.org/10.1111/j.1471-4159.2010.06967.x
Autor:
Linda MacArthur
Publikováno v:
Journal of Neurochemistry. 67:2256-2264
Chromaffin cells of the adrenal medulla are neural crest-derived neuroendocrine cells that express neuropeptide genes in vivo and in vitro. As such these cells are useful for examining tissue- and cell-specific regulation of the enkephalin gene. We p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a330a0430dcc263fc863e0c6dd646724
https://doi.org/10.1046/j.1471-4159.1996.67062256.x
https://doi.org/10.1046/j.1471-4159.1996.67062256.x
Autor:
Susan G. Fisher, Carrie B. Peltz, Timothy R. Mhyre, Mark Mapstone, Derick R. Peterson, Michael Nazar, Dan J Berlau, William J. Hall, Ming Tan, Massimo S. Fiandaca, Claudia H. Kawas, Howard J. Federoff, Steven A. Rich, Linda MacArthur, Amrita K. Cheema, James M Haley, Xiaogang Zhong
Publikováno v:
Mapstone, M; Cheema, AK; Fiandaca, MS; Zhong, X; Mhyre, TR; Macarthur, LH; et al.(2014). Plasma phospholipids identify antecedent memory impairment in older adults. Nature Medicine, 20(4), 415-418. doi: 10.1038/nm.3466. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/50n9b66b
Alzheimer's disease causes a progressive dementia that currently affects over 35 million individuals worldwide and is expected to affect 115 million by 2050 (ref. 1). There are no cures or disease-modifying therapies, and this may be due to our inabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdbdc4eb4d7aac4b960e60dbf7b5bf50
https://pubmed.ncbi.nlm.nih.gov/28119051
https://pubmed.ncbi.nlm.nih.gov/28119051
Autor:
Maclean, Linda MacArthur
Completing activities of daily life relies on using both cognitive and physical resources efficiently, but these are affected by age. This may be due either to an age-related reduction in the resources we have available for carrying out tasks or to a
Externí odkaz:
http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.588938
Autor:
Milton L. Brown, Sivanesan Dakshanamurthy, Scott Grindrod, Aparna Baheti, Linda MacArthur, Li Zhang, Thomas H. Walls, Dawn Béraud, Manoj K. Patel
Publikováno v:
Bioorganicmedicinal chemistry. 20(17)
Here we report on a novel fluorescent analog of phenytoin as a potential inhibitor of neuropathic pain with potential use as an imaging agent. Compound 2 incorporated a heptyl side chain and dansyl moiety onto the parent compound phenytoin and produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35be7caec182e03fc8e694e838e5963d
https://pubmed.ncbi.nlm.nih.gov/22863530
https://pubmed.ncbi.nlm.nih.gov/22863530
Publikováno v:
Scopus-Elsevier
The gene encoding the neuropeptide galanin is upregulated by second messenger signal transduction pathways in bovine chromaffin cells. To identify its transcriptional regulatory elements, 5'-flanking sequences of the galanin gene were transiently tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a283f95b6d6def00aa1bad47ee02f5
https://doi.org/10.1016/s0021-9258(17)37450-1
https://doi.org/10.1016/s0021-9258(17)37450-1
Autor:
Paramita Das, Barbara S. Bregman, Nicole Hockenbury, Haining Dai, Linda MacArthur, Marietta McAtee
Publikováno v:
Restorative neurology and neuroscience. 29(2)
Purpose: The effect of activity based therapies on restoring forelimb function in rats was evaluated when initiated one month after a cervical spinal cord injury. Methods: Adult rats received a unilateral over-hemisection of the spinal cord at C4/5,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fef721f65cd733bc53b341077ccf20f
https://pubmed.ncbi.nlm.nih.gov/21701061
https://pubmed.ncbi.nlm.nih.gov/21701061
Autor:
Manoj K. Patel, Eliseu O. De Oliveira, Aparna Baheti, K. Graf, Linda MacArthur, Sivanesan Dakshanamurthy, Milton L. Brown, Kan Wang, Hye-Sik Kong, Mikell Paige
Publikováno v:
Bioorganicmedicinal chemistry. 19(14)
Hermitamides A and B are lipopeptides isolated from a Papau New Guinea collection of the marine cyanobacterium Lyngbya majuscula. We hypothesized that the hermitamides are ligands for the human voltage-gated sodium channel (hNa(V)) based on their str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7668f5555938d64550bbb9b795c5d22
https://pubmed.ncbi.nlm.nih.gov/21683602
https://pubmed.ncbi.nlm.nih.gov/21683602
Publikováno v:
Journal of Physiology-Paris. 86:89-98
The molecular mechanisms regulating neuropeptide and secretory protein biosynthesis in neuroendocrine cells were examined using the prototype neuropeptide and secretory proteins enkephalin and chromogranin A (CGA). Treatment with the secretogogue nic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7e0595dd1216bc633330e6aa8ee24c
https://doi.org/10.1016/s0928-4257(05)80012-9
https://doi.org/10.1016/s0928-4257(05)80012-9