Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Linda, Sperling"'
Autor:
Diamantis Sellis, Frédéric Guérin, Olivier Arnaiz, Walker Pett, Emmanuelle Lerat, Nicole Boggetto, Sascha Krenek, Thomas Berendonk, Arnaud Couloux, Jean-Marc Aury, Karine Labadie, Sophie Malinsky, Simran Bhullar, Eric Meyer, Linda Sperling, Laurent Duret, Sandra Duharcourt
Publikováno v:
PLoS Biology, Vol 19, Iss 7, p e3001309 (2021)
Ciliates are unicellular eukaryotes with both a germline genome and a somatic genome in the same cytoplasm. The somatic macronucleus (MAC), responsible for gene expression, is not sexually transmitted but develops from a copy of the germline micronuc
Externí odkaz:
https://doaj.org/article/8e5fba611f9b49129c2ba90f7930162b
Autor:
Andrea Frapporti, Caridad Miró Pina, Olivier Arnaiz, Daniel Holoch, Takayuki Kawaguchi, Adeline Humbert, Evangelia Eleftheriou, Bérangère Lombard, Damarys Loew, Linda Sperling, Karine Guitot, Raphaël Margueron, Sandra Duharcourt
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
H3K9me3 and H3K27me3 chromatin silencing marks are usually deposited by different SET-domain proteins. Here the authors show that the Enhancer-of-zeste-like protein Ezl1, from the unicellular eukaryote Paramecium tetraurelia, catalyzes methylation of
Externí odkaz:
https://doaj.org/article/a486884fd7c44e3eb795b8444d15483e
Autor:
Olivier Arnaiz, Erwin Van Dijk, Mireille Bétermier, Maoussi Lhuillier-Akakpo, Augustin de Vanssay, Sandra Duharcourt, Erika Sallet, Jérôme Gouzy, Linda Sperling
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-12 (2017)
Abstract Background The 15 sibling species of the Paramecium aurelia cryptic species complex emerged after a whole genome duplication that occurred tens of millions of years ago. Given extensive knowledge of the genetics and epigenetics of Paramecium
Externí odkaz:
https://doaj.org/article/40d2a488c6ba4f68a0c3648f9b553c23
Autor:
Frédéric Guérin, Olivier Arnaiz, Nicole Boggetto, Cyril Denby Wilkes, Eric Meyer, Linda Sperling, Sandra Duharcourt
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-17 (2017)
Abstract Background DNA elimination is developmentally programmed in a wide variety of eukaryotes, including unicellular ciliates, and leads to the generation of distinct germline and somatic genomes. The ciliate Paramecium tetraurelia harbors two ty
Externí odkaz:
https://doaj.org/article/20624ba6fe6a449fae4f28084a2394d8
Autor:
Jean-Francois Gout, Yue Hao, Parul Johri, Olivier Arnaiz, Thomas G Doak, Simran Bhullar, Arnaud Couloux, Fréderic Guérin, Sophie Malinsky, Alexey Potekhin, Natalia Sawka, Linda Sperling, Karine Labadie, Eric Meyer, Sandra Duharcourt, Michael Lynch
Publikováno v:
Molecular Biology and Evolution. 40
Whole-genome duplications (WGDs) have shaped the gene repertoire of many eukaryotic lineages. The redundancy created by WGDs typically results in a phase of massive gene loss. However, some WGD–derived paralogs are maintained over long evolutionary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8db602732ba7e907630d93b161a54f1c
https://doi.org/10.1093/molbev/msad107
https://doi.org/10.1093/molbev/msad107
Autor:
Mélanie Bazin-Gélis, Evangelia Eleftheriou, Coralie Zangarelli, Gaëlle Lelandais, Linda Sperling, Olivier Arnaiz, Mireille Bétermier
Multinucleate cells are found in many eukaryotes, but how multiple nuclei coordinate their functions is still poorly understood. In the cytoplasm of the ciliateParamecium tetraurelia, two micronuclei (MIC) serving sexual reproduction coexist with a s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2ab28ccc7cd048670fe8ae4c10b9a19
https://doi.org/10.1101/2023.04.16.537068
https://doi.org/10.1101/2023.04.16.537068
Autor:
Stefano Gnan, Mélody Matelot, Marion Weiman, Olivier Arnaiz, Frédéric Guérin, Linda Sperling, Mireille Bétermier, Claude Thermes, Chun-Long Chen, Sandra Duharcourt
Publikováno v:
Genome Research. 32:699-709
Eukaryotic genes are interrupted by introns that must be accurately spliced from mRNA precursors. With an average length of 25 nt, the more than 90,000 introns of Paramecium tetraurelia stand among the shortest introns reported in eukaryotes. The mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41d905871e4c1c85006e7449d597e6f7
https://doi.org/10.1101/gr.276125.121
https://doi.org/10.1101/gr.276125.121
Autor:
Julien Bischerour, Simran Bhullar, Cyril Denby Wilkes, Vinciane Régnier, Nathalie Mathy, Emeline Dubois, Aditi Singh, Estienne Swart, Olivier Arnaiz, Linda Sperling, Mariusz Nowacki, Mireille Bétermier
Publikováno v:
eLife, Vol 7 (2018)
The domestication of transposable elements has repeatedly occurred during evolution and domesticated transposases have often been implicated in programmed genome rearrangements, as remarkably illustrated in ciliates. In Paramecium, PiggyMac (Pgm), a
Externí odkaz:
https://doaj.org/article/b92d5bf9a11e454582d088cafcb4da74
Autor:
Martine B. Fairbanks, Linda Sperling
Publikováno v:
Journal of Gerontology and Geriatrics. 69:19-25
Background. Polypharmacy, or taking five or more medications daily, can lead to poor medication compliance and an increased risk for adverse drug-to-drug interactions that may eventually lead to death. The study was designed to explore the questions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d342b23bb7f57724e0538bd3b5ca7c3e
https://doi.org/10.36150/2499-6564-447
https://doi.org/10.36150/2499-6564-447
Autor:
Stefano, Gnan, Mélody, Matelot, Marion, Weiman, Olivier, Arnaiz, Frédéric, Guérin, Linda, Sperling, Mireille, Bétermier, Claude, Thermes, Chun-Long, Chen, Sandra, Duharcourt
Publikováno v:
Genome research. 32(4)
Eukaryotic genes are interrupted by introns that must be accurately spliced from mRNA precursors. With an average length of 25 nt, the more than 90,000 introns of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5b0a3e27961bf2f1260e6f3a50499f0
https://pubmed.ncbi.nlm.nih.gov/35264448
https://pubmed.ncbi.nlm.nih.gov/35264448