Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Linda, Cato"'
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Imaging tools for evaluating progression of Alzheimer’s disease have been lacking. Here the authors develop a blood brain barrier-permeable Aß probe based on a radiolabelled, anti-Aß antibody, and report age-dependent brain uptake visualized in v
Externí odkaz:
https://doaj.org/article/6ff8814765814c6eabc58af15ab9f554
Autor:
Lars Lannfelt, Stina Syvänen, Linda Cato, Dag Sehlin, Gunnar Antoni, Xiaotian T. Fang, Jonas Eriksson, Ulrika Yngve
Publikováno v:
Neuropharmacology. 113:293-300
Alzheimer's disease (AD) is characterized by aggregation of amyloid beta (Aβ) into insoluble plaques. Intermediates, Aβ oligomers (Aβo), appear to be the mechanistic cause of disease. The de facto PET AD ligand, [11C]PIB, binds and visualizes Aβ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80aa840a62a14c322cf9cb51d03590a9
https://doi.org/10.1016/j.neuropharm.2016.10.009
https://doi.org/10.1016/j.neuropharm.2016.10.009
Autor:
Xiaotian T, Fang, Jonas, Eriksson, Gunnar, Antoni, Ulrika, Yngve, Linda, Cato, Lars, Lannfelt, Dag, Sehlin, Stina, Syvänen
Publikováno v:
Neuropharmacology. 113
Alzheimer's disease (AD) is characterized by aggregation of amyloid beta (Aβ) into insoluble plaques. Intermediates, Aβ oligomers (Aβo), appear to be the mechanistic cause of disease. The de facto PET AD ligand, [
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b370d8f2dfca34ac973271db71eaef4e
https://pubmed.ncbi.nlm.nih.gov/27743932
https://pubmed.ncbi.nlm.nih.gov/27743932
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Nature Communications
Nature Communications
Owing to their specificity and high-affinity binding, monoclonal antibodies have potential as positron emission tomography (PET) radioligands and are currently used to image various targets in peripheral organs. However, in the central nervous system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7189b5b485ed3dc7c48607c2b8443d55
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-282384
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-282384
