Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lincong Jin"'
Autor:
Yibo Zuo, Qian Feng, Lincong Jin, Fan Huang, Ying Miao, Jin Liu, Ying Xu, Xiangjie Chen, Hongguang Zhang, Tingting Guo, Yukang Yuan, Liting Zhang, Jun Wang, Hui Zheng
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
LUBAC is involved in adding linear ubiquitin chains to important immune signaling proteins. Here the authors show that this mechanism is effective in inhibiting STAT1-mediated interferon signaling, and that the deubiquitinase OTULIN can remove these
Externí odkaz:
https://doaj.org/article/4c4454e0aa0248c9a214db9c6f0ed420
Autor:
Hong-Guang Zhang, Jing Guo, Yukang Yuan, Yibo Zuo, Jin Liu, Li Zhu, Ying Miao, Xiangjie Chen, Lincong Jin, Fan Huang, Tengfei Ren, Jiuyi He, Weifeng Shi, Zhenke Wen, Chuanwu Zhu, Hui Zheng, Chunsheng Dong, Feng Qian
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Nef is an accessory protein encoded by human immunodeficiency virus type-1 (HIV-1) and plays important roles in regulating HIV-1 infection and viral replication. Interestingly, HIV-1 Nef can promote degradation of numerous host proteins to disrupt ce
Externí odkaz:
https://doaj.org/article/2b8d9e4fa137486a9cacaf4c10c04620
Autor:
Jin Liu, Lincong Jin, Xiangjie Chen, Yukang Yuan, Yibo Zuo, Ying Miao, Qian Feng, Hongguang Zhang, Fan Huang, Tingting Guo, Liting Zhang, Li Zhu, Feng Qian, Chuanwu Zhu, Hui Zheng
Publikováno v:
PLoS Pathogens, Vol 16, Iss 1, p e1008215 (2020)
CREB-binding protein (CBP) participates in numerous transcription events. However, cell-intrinsic inhibitors of CBP are poorly defined. Here, we found that cellular USP12 interacts with the HAT domain of CBP and inhibits CBP's acetyltransferase activ
Externí odkaz:
https://doaj.org/article/2f15c41d02c747ce9edf838ca12081ac
Autor:
Yibo Zuo, Jiuyi He, Siying Liu, Ying Xu, Jin Liu, Caixia Qiao, Lichao Zang, Wenhuan Sun, Yukang Yuan, Hongguang Zhang, Xiangjie Chen, Lincong Jin, Ying Miao, Fan Huang, Tengfei Ren, Jun Wang, Feng Qian, Chuanwu Zhu, Wei Zhang, Yaobo Liu, Guoqiang Xu, Feng Ma, Hui Zheng
Publikováno v:
Science advances. 8(14)
Interferons (IFNs) have broad-spectrum antiviral activity to resist virus epidemic. However, IFN antiviral efficacy needs to be greatly improved. Here, we reveal that LATS1 is a vital signal transmitter governing full type-I IFN (IFN-I) signaling act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a47d1398aaae8fcd0b27acf025af13a5
https://pubmed.ncbi.nlm.nih.gov/35394840
https://pubmed.ncbi.nlm.nih.gov/35394840
Autor:
Xiangjie Chen, Qian Feng, Tingting Guo, Ying Miao, Fan Huang, Ying Xu, Jun Wang, Liting Zhang, Hong-Guang Zhang, Jin Liu, Lincong Jin, Yukang Yuan, Yibo Zuo, Hui Zheng
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications
Nature Communications
Linear ubiquitination is a critical regulator of inflammatory signaling pathways. However, linearly ubiquitinated substrates and the biological significance of linear ubiquitination is incompletely understood. Here, we show that STAT1 has linear ubiq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a7175a68f6cbc6df460f5b4bdfdb285
https://doi.org/10.1038/s41467-020-14948-z
https://doi.org/10.1038/s41467-020-14948-z
Autor:
Yibo Zuo, Tingting Guo, Ying Miao, Chuanwu Zhu, Hui Zheng, Liting Zhang, Hong-Guang Zhang, Li Zhu, Xiangjie Chen, Fan Huang, Qian Feng, Lincong Jin, Jin Liu, Yukang Yuan, Feng Qian
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 1, p e1008215 (2020)
PLoS Pathogens, Vol 16, Iss 1, p e1008215 (2020)
CREB-binding protein (CBP) participates in numerous transcription events. However, cell-intrinsic inhibitors of CBP are poorly defined. Here, we found that cellular USP12 interacts with the HAT domain of CBP and inhibits CBP’s acetyltransferase act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09116da0bc8716eaa14b42f121f996e4
http://europepmc.org/articles/PMC6961928
http://europepmc.org/articles/PMC6961928
Publikováno v:
Nature Microbiology. 4:1771-1773
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed24c4abdf90158f5615e0264f7fe34
https://doi.org/10.1038/s41564-019-0582-7
https://doi.org/10.1038/s41564-019-0582-7
Autor:
Yang Zhang, Yibo Zuo, Liting Zhang, Tingting Guo, Guoqiang Xu, Fan Huang, Hong-Guang Zhang, Wei Zhang, Wei Li, Hui Zheng, Qian Feng, Yukang Yuan, Ying Miao, Liping Qian, Xiangjie Chen, Chao Liu, Lincong Jin, Jin Liu
Publikováno v:
Molecular Cell. 77:734-747.e7
Mutation and prevalence of pathogenic viruses prompt the development of broad-spectrum antiviral strategies. Viperin is a potent antiviral protein that inhibits a broad range of viruses. Unexpectedly, we found that Viperin protein production in epith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f767fe88eeab424080b9aa6ff90dc5ef
https://doi.org/10.1016/j.molcel.2019.11.003
https://doi.org/10.1016/j.molcel.2019.11.003
Autor:
Lincong Jin, Liping Qian, Jin Liu, Qian Feng, Tingting Guo, Xiangjie Chen, Sidong Xiong, Yukang Yuan, Liting Zhang, Ying Miao, Chunsheng Dong, Kailin Xu, Hui Zheng, Yibo Zuo
Publikováno v:
Nature microbiology. 4(11)
Outbreaks of viral infections are a global health burden. Although type I interferon (IFN-I) exerts broad-spectrum antiviral effects, its antiviral efficacy in host cells is largely restricted by viruses. How the antiviral efficacy of IFN-I can be im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e149b9a681989624d8d5259018e0e2
https://pubmed.ncbi.nlm.nih.gov/31649358
https://pubmed.ncbi.nlm.nih.gov/31649358