Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Lincoln T. Shenje"'
Autor:
Craig Dorrell, Branden Tarlow, Yuhan Wang, Pamela S. Canaday, Annelise Haft, Jonathan Schug, Philip R. Streeter, Milton J. Finegold, Lincoln T. Shenje, Klaus H. Kaestner, Markus Grompe
Publikováno v:
Stem Cell Research, Vol 13, Iss 2, Pp 275-283 (2014)
Pancreatic Lgr5 expression has been associated with organoid-forming epithelial progenitor populations but the identity of the organoid-initiating epithelial cell subpopulation has remained elusive. Injury causes the emergence of an Lgr5+ organoid-fo
Externí odkaz:
https://doaj.org/article/77bfdf5c318448cb9545b2a68586efeb
Autor:
Lincoln T Shenje, Peter Andersen, Hideki Uosaki, Laviel Fernandez, Peter P Rainer, Gun-sik Cho, Dong-ik Lee, Weimin Zhong, Richard P Harvey, David A Kass, Chulan Kwon
Publikováno v:
eLife, Vol 3 (2014)
Cardiac progenitor cells (CPCs) must control their number and fate to sustain the rapid heart growth during development, yet the intrinsic factors and environment governing these processes remain unclear. Here, we show that deletion of the ancient ce
Externí odkaz:
https://doaj.org/article/28fce4bb0d45423fb9e788b539632d97
Autor:
Hideki Uosaki, Peter Andersen, Lincoln T Shenje, Laviel Fernandez, Sofie Lindgren Christiansen, Chulan Kwon
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46413 (2012)
Pluripotent stem cell-derived cardiac progenitor cells (CPCs) have emerged as a powerful tool to study cardiogenesis in vitro and a potential cell source for cardiac regenerative medicine. However, available methods to induce CPCs are not efficient o
Externí odkaz:
https://doaj.org/article/31954bf0604a411ea251256a10c93485
Autor:
Lincoln T Shenje, Loren J Field, Catrin A Pritchard, Christopher J Guerin, Michael Rubart, Mark H Soonpaa, Keng-Leong Ang, Manuel Galiñanes
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e1929 (2008)
Cultured cardiac explants produce a heterogeneous population of cells including a distinctive population of refractile cells described here as small round cardiac explant derived cells (EDCs). The aim of this study was to explore the source, morpholo
Externí odkaz:
https://doaj.org/article/993c4e93a7f24493841753436f9a0374
Proper control of multipotent/stem cell number and fate is essential for ensuing organ formation during development. β1-integrin, a subfamily of cell surface receptors, has a conserved role in maintenance of multipotent/stem cells, including renal p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4674f8b4f79f0e1308e7c4eefbc96baa
https://europepmc.org/articles/PMC5924717/
https://europepmc.org/articles/PMC5924717/
Autor:
Branden D. Tarlow, Yuhan Wang, Lincoln T. Shenje, Philip R. Streeter, Jonathan Schug, Annelise Haft, Milton J. Finegold, Klaus H. Kaestner, Craig Dorrell, Pamela S. Canaday, Markus Grompe
Publikováno v:
Stem Cell Research, Vol 13, Iss 2, Pp 275-283 (2014)
Pancreatic Lgr5 expression has been associated with organoid-forming epithelial progenitor populations but the identity of the organoid-initiating epithelial cell subpopulation has remained elusive. Injury causes the emergence of an Lgr5(+) organoid-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567fb55983c15282c591ca3f2da476bf
https://doi.org/10.1016/j.scr.2014.07.006
https://doi.org/10.1016/j.scr.2014.07.006
Publikováno v:
Trends in Cell Biology. 22:257-265
Notch is an ancient transmembrane receptor with crucial roles in cell-fate choices. Although the 'canonical' Notch pathway and its core members are well established - involving ligand-induced cleavage of Notch for transcriptional regulation - it has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6cd25e6d9ebfe94d5ff67c67f1d7c2
https://doi.org/10.1016/j.tcb.2012.02.003
https://doi.org/10.1016/j.tcb.2012.02.003
Autor:
Loren J. Field, Sean Reuter, Lincoln T. Shenje, Manuel Galiñanes, Mark H. Soonpaa, Keng Leong Ang, Michael Rubart
Publikováno v:
American Journal of Physiology-Cell Physiology. 298:C1603-C1609
Accurate nuclear identification is crucial for distinguishing the role of cardiac myocytes in intrinsic and experimentally induced regenerative growth of the myocardium. Conventional histologic analysis of myocyte nuclei relies on the optical section
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a09037c1278d35f46b66c3ec3e872b
https://doi.org/10.1152/ajpcell.00435.2009
https://doi.org/10.1152/ajpcell.00435.2009
Autor:
Derek Chin, Manuel Galiñanes, Keng Leong Ang, Shajil Chalil, Lincoln T. Shenje, Chandrashekhar A. Kubal, Lizelle Bernhardt, Lakshmi Srinivasan, Paul W X Foley, Suzanne Stevens, Francisco Leyva
Publikováno v:
Nature Clinical Practice Cardiovascular Medicine. 5:663-670
Studies of the transplantation of autologous bone marrow cells (BMCs) in patients with chronic ischemic heart disease have assessed effects on viable, peri-infarct tissue. We conducted a single-blinded, randomized, controlled study to investigate whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2107910056abd4bd34f4d0c5e0eb3f4
https://doi.org/10.1038/ncpcardio1321
https://doi.org/10.1038/ncpcardio1321
Autor:
Gun Sik Cho, Richard P. Harvey, Lincoln T. Shenje, Chulan Kwon, Peter Andersen, Hideki Uosaki, Laviel Fernandez, Dong Ik Lee, Peter P. Rainer, David A. Kass, Weimin Zhong
Publikováno v:
eLife, Vol 3 (2014)
eLife
eLife
Cardiac progenitor cells (CPCs) must control their number and fate to sustain the rapid heart growth during development, yet the intrinsic factors and environment governing these processes remain unclear. Here, we show that deletion of the ancient ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd376abaeb6d088548ce6a595a3df82
https://doi.org/10.7554/elife.02164
https://doi.org/10.7554/elife.02164