Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Lincoln ST"'
Autor:
Vasily Giannakeas, Amanda Smith, Hong Wang, Harriet Feilotter, Melyssa Aronson, Andrea Eisen, Raymond H Kim, Jordan Lerner-Ellis, Steven A Narod, Laszlo Radvanyi, Kathleen Bell, Jane Bayani, Ian King, DAVID MALKIN, Kathy Chun, Irene L Andrulis, Bailey Gallinger, Anita Villani, George Charames, Lincoln Stein, Sarah Sawyer, Karen Panabaker, Philip Awadalla, Trevor Pugh, Mohammad Reza Akbari, Peter Goodhand, Brandon Chan, Yael Silberman, Jennifer Brooks, Melanie Spears, Kirsten M Farncombe, Lauren K Hughes, Elif Tuzlali, Michelle D Brazas, Melissa Cable-Cibula, Melanie Courtot, Jamie Harland, Katie Lark, Ellen MacDougall, Alison Rusnak, Christopher Deutschman, Chiquita Hessels, Brittney Johnstone, Talia Mancuso, Kelly McDonald, Meredith McLaren, Karen Ott, Stephen Parrott, Wendy Parulekar, Aaron Pollet, Laila Schenkel, Larissa Waldman, Martin Yaffe
Publikováno v:
BMJ Open, Vol 14, Iss 11 (2024)
Introduction In Canada, care for individuals with hereditary cancer is fragmented across the provinces and territories, with carriers of pathogenic variants in cancer-susceptibility genes seeing multiple doctors and often advocating for their own man
Externí odkaz:
https://doaj.org/article/5933192ab0ec45c4b3bb3c64b90ddbd6
Autor:
Lauren Hughes, Kirsten Farncombe, Michelle Brazas, Melyssa Aronson, Kathleen Bell, Brandon Chan, Andrea Eisen, Harriet Feilotter, Bailey Gallinger, Jordan Lerner-Ellis, David Malkin, Ellen MacDougall, Steven Narod, Karen Panabaker, Trevor Pugh, Sarah Sawyer, Alison Rusnak, Andrea Vaags, Laszlo Radvanyi, Lincoln Stein, Raymond Kim
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100073- (2023)
Externí odkaz:
https://doaj.org/article/c38002f5ac4340b7a33c4bab75bdf9a1
Publikováno v:
Quality Advancement in Nursing Education, Vol 8, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/c7638b64f87f4af18ff4eed7454760ad
Autor:
Shimin Shuai, PCAWG Drivers and Functional Interpretation Working Group, Steven Gallinger, Lincoln Stein, PCAWG Consortium
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Analysis of cancer genome sequencing data has enabled the discovery of driver mutations. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium the authors present DriverPower, a software package that identifies coding
Externí odkaz:
https://doaj.org/article/142b65513ccf441182a79c2cf78b29df
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 8, p e1007261 (2020)
We describe JBrowse Connect, an optional expansion to the JBrowse genome browser, targeted at developers. JBrowse Connect allows live messaging, notifications for new annotation tracks, heavy-duty analyses initiated by the user from within the browse
Externí odkaz:
https://doaj.org/article/29c8301d40cb4631bb498cb25fbc654c
Akademický článek
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Akademický článek
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Autor:
Irina Kalatskaya, Quang M. Trinh, Melanie Spears, John D. McPherson, John M. S. Bartlett, Lincoln Stein
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-18 (2017)
Abstract Background A key step in cancer genome analysis is the identification of somatic mutations in the tumor. This is typically done by comparing the genome of the tumor to the reference genome sequence derived from a normal tissue taken from the
Externí odkaz:
https://doaj.org/article/3874531847174a59b6e298ac61eafc3b
Autor:
Fan Yang, Dae-Kyum Kim, Hidewaki Nakagawa, Shuto Hayashi, Seiya Imoto, Lincoln Stein, Frederick P Roth
Publikováno v:
PLoS Genetics, Vol 15, Iss 7, p e1008227 (2019)
Somatic mutations in protein-coding regions can generate 'neoantigens' causing developing cancers to be eliminated by the immune system. Quantitative estimates of the strength of this counterselection phenomenon have been lacking. We quantified the e
Externí odkaz:
https://doaj.org/article/55fc394ae68a48379e95f70caabfbcaa
Publikováno v:
F1000Research, Vol 8 (2019)
The precision medicine paradigm is centered on therapies targeted to particular molecular entities that will elicit an anticipated and controlled therapeutic response. However, genetic alterations in the drug targets themselves or in genes whose prod
Externí odkaz:
https://doaj.org/article/785f588ef95741b3ae9f3389bc0d9b80