Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Lincoln Edwards"'
Autor:
Susana M. Beltrán, Justin Bobo, Ahmed Habib, Chowdari V. Kodavali, Lincoln Edwards, Priyadarshini Mamindla, Rebecca E. Taylor, Philip R. LeDuc, Pascal O. Zinn
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The ability to model physiological systems through 3D neural in-vitro systems may enable new treatments for various diseases while lowering the need for challenging animal and human testing. Creating such an environment, and even more impact
Externí odkaz:
https://doaj.org/article/ae28db549b3f49a3a8976bb560015074
Autor:
Susana M. Beltrán, Justin Bobo, Ahmed Habib, Chowdari V. Kodavali, Lincoln Edwards, Priyadarshini Mamindla, Rebecca E. Taylor, Philip R. LeDuc, Pascal O. Zinn
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/9d755f9b39d2466f8a64a73945c5ae48
Autor:
Meagan Hoppe, Ahmed Habib, Riya Desai, Lincoln Edwards, Chowdari Kodavali, Natalie Sandel Sherry Psy, Pascal O. Zinn
Publikováno v:
Frontiers in Molecular Medicine, Vol 3 (2023)
Human brain organoids are models derived from human embryonic or induced pluripotent stem cells that mimic basic cerebral microanatomy and demonstrate simple functional neuronal networks. Brain organoids have been a rapidly expanding avenue for biome
Externí odkaz:
https://doaj.org/article/cd113cecd8384eee8c144c8e56f96b08
Autor:
Nicolina Jovanovich, Ahmed Habib, Jeffery Head, Austin Anthony, Lincoln Edwards, Pascal O. Zinn
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/804cd43538904a8f9e0f3f17687f3eb9
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/4990fc48f8a7434f969e1ab9ecb636b4
Autor:
Jamison Beiriger, Ahmed Habib, Nicolina Jovanovich, Chowdari V. Kodavali, Lincoln Edwards, Nduka Amankulor, Pascal O. Zinn
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Glioblastoma (GBM) is a malignant tumor with a median survival rate of 15-16 months with standard care; however, cases of successful treatment offer hope that an enhanced understanding of the pathology will improve the prognosis. The cell of origin i
Externí odkaz:
https://doaj.org/article/d54c18cc0db0453d927cb058ec2c6e40
Autor:
Amanda Linkous, Demosthenes Balamatsias, Matija Snuderl, Lincoln Edwards, Ken Miyaguchi, Teresa Milner, Batsheva Reich, Leona Cohen-Gould, Andrew Storaska, Yasumi Nakayama, Emily Schenkein, Richa Singhania, Stefano Cirigliano, Tarig Magdeldin, Ying Lin, Gouri Nanjangud, Kalyani Chadalavada, David Pisapia, Conor Liston, Howard A. Fine
Publikováno v:
Cell Reports, Vol 26, Iss 12, Pp 3203-3211.e5 (2019)
Summary: The prognosis of patients with glioblastoma (GBM) remains dismal, with a median survival of approximately 15 months. Current preclinical GBM models are limited by the lack of a “normal” human microenvironment and the inability of many tu
Externí odkaz:
https://doaj.org/article/f28ebd0f3f8540688e121a8ec45550af
Autor:
Chibawanye I Ene, Lincoln Edwards, Gregory Riddick, Mehmet Baysan, Kevin Woolard, Svetlana Kotliarova, Chen Lai, Galina Belova, Maggie Cam, Jennifer Walling, Ming Zhou, Holly Stevenson, Hong Sug Kim, Keith Killian, Timothy Veenstra, Rolanda Bailey, Hua Song, Wei Zhang, Howard A Fine
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51407 (2012)
Histone methylation regulates normal stem cell fate decisions through a coordinated interplay between histone methyltransferases and demethylases at lineage specific genes. Malignant transformation is associated with aberrant accumulation of repressi
Externí odkaz:
https://doaj.org/article/101956149d3b4e88aa7bbf52ca44aadf
Publikováno v:
Immunotherapy. 15:383-396
High-grade gliomas (HGGs) continue to be some of the most devastating diseases in the USA. Despite extensive efforts, the survival of HGG patients has remained relatively stagnant. Chimeric antigen receptor (CAR) T-cell immunotherapy has recently bee
Autor:
Howard A. Fine, Olivier Elemento, Matija Snuderl, David J. Pisapia, Rohan Ramakrishna, Theodore H. Schwartz, Richa Singhania, Lincoln Edwards, Ken Miyaguchi, Amanda Linkous, Yang Hu, James G. Nicholson, Stefano M. Cirigliano, Allison R. Pine
Supplementary figures and tables with Figure legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0e13a8da6b8a938720fcb87459cd7a
https://doi.org/10.1158/2159-8290.22535305.v1
https://doi.org/10.1158/2159-8290.22535305.v1