Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Linbin Lu"'
Autor:
Junya Yan, Shibo Wang, Jing Zhang, Qiangqiang Yuan, Xianchun Gao, Nannan Zhang, Yan Pan, Haohao Zhang, Kun Liu, Jun Yu, Linbin Lu, Hui Liu, Xiaoliang Gao, Sheng Zhao, Wenyao Zhang, Abudurousuli Reyila, Yu Qi, Qiujin Zhang, Shundong Cang, Yuanyuan Lu, Yanglin Pan, Yan Kong, Yongzhan Nie
Publikováno v:
Cancer Biology & Medicine, Vol 21, Iss 3, Pp 252-266 (2024)
Objective: DNA damage response (DDR) deficiency has emerged as a prominent determinant of tumor immunogenicity. This study aimed to construct a DDR-related immune activation (DRIA) signature and evaluate the predictive accuracy of the DRIA signature
Externí odkaz:
https://doaj.org/article/121a7fe4cb324772b4cd2853d6f3efbc
Autor:
Xianchun Gao, Gang Li, Jingyu Deng, Lulu Zhao, Weili Han, Nannan Zhang, Yunhe Gao, Linbin Lu, Shibo Wang, Jun Yu, Junya Yan, Gan Zhang, Rui Peng, Rupeng Zhang, Yu Fu, Fang He, Junguo Hu, Wanqing Wang, Ping Fan, Cen Si, Peng Gao, Han Liang, Huanqiu Chen, Gang Ji, Lei Shang, Qingchuan Zhao, Zhiyi Zhang, Shaoqi Yang, Zhenning Wang, Hongqing Xi, Yingtai Chen, Kaichun Wu, Yongzhan Nie
Publikováno v:
The Lancet Regional Health. Western Pacific, Vol 45, Iss , Pp 101031- (2024)
Summary: Background: Recurrence following radical resection in patients with stage IB gastric cancer (GC) is not uncommon. However, whether postoperative adjuvant chemotherapy could reduce the risk of recurrence in stage IB GC remains contentious. Me
Externí odkaz:
https://doaj.org/article/2ec5192a62ea4530a57cffc5ea2b13a3
Autor:
Linbin Lu, Wenzheng Fang, Jun Yu, Xianchun Gao, Xinlin Wang, Yan Pan, Weili Han, Junya Yan, Huahong Xie, Liping Yao, Jianjun Yang, Jianyong Zheng, Liu Hong, Jipeng Li, Mengbin Li, Lei Shang, Kaichun Wu, Gang Ji, Yongzhan Nie
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundBaseline serological biomarkers have the potential to predict the benefits of adjuvant chemotherapy in patients with gastric cancer. However, the fluctuating nature of postoperative recurrence risk makes precise treatment challenging. We ai
Externí odkaz:
https://doaj.org/article/263fed1507f641319725d98533820e63
Autor:
Hong Chen, Junxian Wu, Wanting Guo, Lihang Yang, Linbin Lu, Yihong Lin, Xuewen Wang, Yan Zhang, Xi Chen
Publikováno v:
Cancer Medicine, Vol 12, Iss 5, Pp 5275-5292 (2023)
Abstract Background Patients with early esophageal cancer (EC) receive individualized therapy based on their lymph node metastasis (LNM) and distant metastasis (DM) status; however, deficiencies in current clinical staging techniques and the issue of
Externí odkaz:
https://doaj.org/article/f22c325c368d42daad7761ab0ab71541
Autor:
Yan Pan, Linbin Lu, Huan Liu, Di Chen, Ning Han, Ruirong Yao, Xinlin Wang, Xianchun Gao, Jun Yu, Ling Chen, Fenli Zhou, Guangjun Hao, Yuanyuan Lu, Mengbin Li, Guangbin He, Fei Kang, Zengshan Li, Yongqiang Tang, Jinsong Zhang, Lichun Wei, Yongzhan Nie
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundTrastuzumab-containing chemotherapy is the first-line treatment for advanced gastric cancer (GC) with HER2 positive. Although PD-1 inhibitors significantly improved the outcome of GC patient’s refractory to previous chemotherapy regimens,
Externí odkaz:
https://doaj.org/article/68020205dea246918405b707181375d8
Autor:
Linbin Lu, Lujun Shen, Zhixian Wu, Yanhong Shi, Peifeng Hou, Zengfu Xue, Cheng Lin, Xiong Chen
Publikováno v:
EClinicalMedicine, Vol 47, Iss , Pp 101391- (2022)
Summary: Background: α-fetoprotein (AFP) response has been proven a key tumor marker for hepatocellular carcinoma (HCC), but its definition remains controversial. This study aims to characterize AFP trajectories after transarterial chemoembolization
Externí odkaz:
https://doaj.org/article/c55293515b764c6aaca61119814286d2
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundThe selection criteria for hepatic resection (HR) in intermediate-stage (IM) hepatocellular carcinoma (HCC) are still controversial. We used real-world data to evaluate the overall survival (OS) in treatment with HR or transarterial chemoem
Externí odkaz:
https://doaj.org/article/d19d7020d113421ab4505fbbe3122ec9
Autor:
Xiong Chen, Jingnan Liu, Linbin Lu, Zhimin Su, Peichan Zheng, Zhixian Wu, Huimin He, Shan Lin
Publikováno v:
BMJ Open, Vol 10, Iss 11 (2020)
Objectives To explore the non-linear relationship between platelet count (PLT) and hepatocellular carcinoma (HCC) overall survival (OS).Setting The study was done in Sun Yat-sen University Cancer Center (SYSUCC) from January 2007 to May 2012, a total
Externí odkaz:
https://doaj.org/article/e625f2efb1964fdfaff2135cbdce217a
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
PurposeWe performed this systematic review and meta-analysis to assess the incidence of fatal adverse events that were associated with the use of programmed cell death ligand 1 (PD-L1) inhibitors, to describe them and to statistically depict factors
Externí odkaz:
https://doaj.org/article/cd4bfece169b45ad9bb789f97ad16a5d
Autor:
Linbin Lu, Tingting Zhuang, Erqian Shao, Yanhong Liu, Huimin He, Zhimin Shu, Yan Huang, Yichen Yao, Shan Lin, Shaoqin Lin, Xi Chen, Xiong Chen
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0221964 (2019)
BackgroundPreclinical studies showed that antibiotic exposure played a role in clinical outcomes in patients with chemotherapy via modulation of microbiota. However, it remains unknown whether antibiotic exposure during the bevacizumab therapy affect
Externí odkaz:
https://doaj.org/article/92ff405dca2e46d4a429b2e3aaf14a8e