Výsledky vyhledávání - "Lina Y. Cheuy"

Table S2 from Preclinical Development and First-in-Human Imaging of the Integrin αvβ6 with [18F]αvβ6-Binding Peptide in Metastatic Carcinoma

Autor: Julie L. Sutcliffe, Edward J. Kim, Cameron C. Foster, Ryan A. Davis, Megan E. Daly, Helen K. Chew, Lina Y. Cheuy, Richard J. Bold, Sven H. Hausner

Shows the biodistribution data for [18F]αvβ6-BP in mice bearing paired αvβ6-expressing DX3puroβ6 and non-αvβ6-expressing DX3puro xenograft tumors at 1, 2 and 4 h p.i. and at 1 h p.i. after pre-administration of blocking peptide. Tissue uptake

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78af266f4811fbf64af07f8e9bde8240
https://doi.org/10.1158/1078-0432.22467603.v1

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Data from Preclinical Development and First-in-Human Imaging of the Integrin αvβ6 with [18F]αvβ6-Binding Peptide in Metastatic Carcinoma

Autor: Julie L. Sutcliffe, Edward J. Kim, Cameron C. Foster, Ryan A. Davis, Megan E. Daly, Helen K. Chew, Lina Y. Cheuy, Richard J. Bold, Sven H. Hausner

Purpose:The study was undertaken to develop and evaluate the potential of an integrin αvβ6-binding peptide (αvβ6-BP) for noninvasive imaging of a diverse range of malignancies with PET.Experimental Design:The peptide αvβ6-BP was prepared on sol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405e7502a084ce6f15ffd02e8f1fe0fa
https://doi.org/10.1158/1078-0432.c.6526695.v1

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Table S4 from Preclinical Development and First-in-Human Imaging of the Integrin αvβ6 with [18F]αvβ6-Binding Peptide in Metastatic Carcinoma

Autor: Julie L. Sutcliffe, Edward J. Kim, Cameron C. Foster, Ryan A. Davis, Megan E. Daly, Helen K. Chew, Lina Y. Cheuy, Richard J. Bold, Sven H. Hausner

Shows the maximum standard uptake values (SUVmax) for primary and metastatic lesions observed in the three subjects, decay corrected to the time of injection.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a32bf70a8c8e78c3c2fa72d8a892413b
https://doi.org/10.1158/1078-0432.22467597

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Figure S2 from Preclinical Development and First-in-Human Imaging of the Integrin αvβ6 with [18F]αvβ6-Binding Peptide in Metastatic Carcinoma

Autor: Julie L. Sutcliffe, Edward J. Kim, Cameron C. Foster, Ryan A. Davis, Megan E. Daly, Helen K. Chew, Lina Y. Cheuy, Richard J. Bold, Sven H. Hausner

Shows the in vivo stability of [18F]αvβ6-BP in human blood. Representative radio-HPLC of blood sample taken 30 min post injection. Top: Sample only; bottom: sample spiked with [18F]αvβ6-BP. X-axis: retention time [min]; Y-axis: detector response

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62c46e86ac37f7576a9f3f73d85ecbe1
https://doi.org/10.1158/1078-0432.22467612.v1

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Supplementary Methods from Preclinical Development and First-in-Human Imaging of the Integrin αvβ6 with [18F]αvβ6-Binding Peptide in Metastatic Carcinoma

Autor: Julie L. Sutcliffe, Edward J. Kim, Cameron C. Foster, Ryan A. Davis, Megan E. Daly, Helen K. Chew, Lina Y. Cheuy, Richard J. Bold, Sven H. Hausner

Describes additional methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df5ae43674db2d9248b8862f34eef09
https://doi.org/10.1158/1078-0432.22467609.v1

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Table S1 from Preclinical Development and First-in-Human Imaging of the Integrin αvβ6 with [18F]αvβ6-Binding Peptide in Metastatic Carcinoma

Autor: Julie L. Sutcliffe, Edward J. Kim, Cameron C. Foster, Ryan A. Davis, Megan E. Daly, Helen K. Chew, Lina Y. Cheuy, Richard J. Bold, Sven H. Hausner

Shows the quality assurance release criteria for [18F]αvβ6-BP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda1356c5e69d4feb6521302b0c95ffc
https://doi.org/10.1158/1078-0432.22467606.v1

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Table S3 from Preclinical Development and First-in-Human Imaging of the Integrin αvβ6 with [18F]αvβ6-Binding Peptide in Metastatic Carcinoma

Autor: Julie L. Sutcliffe, Edward J. Kim, Cameron C. Foster, Ryan A. Davis, Megan E. Daly, Helen K. Chew, Lina Y. Cheuy, Richard J. Bold, Sven H. Hausner

Shows the maximum standard uptake values (SUVmax) at the 1 and 3 hour time points for the five subjects, decay corrected to the time of injection.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bcc6742ff655d8efa3bd3baa869b834
https://doi.org/10.1158/1078-0432.22467600

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Figure S1 from Preclinical Development and First-in-Human Imaging of the Integrin αvβ6 with [18F]αvβ6-Binding Peptide in Metastatic Carcinoma

Autor: Julie L. Sutcliffe, Edward J. Kim, Cameron C. Foster, Ryan A. Davis, Megan E. Daly, Helen K. Chew, Lina Y. Cheuy, Richard J. Bold, Sven H. Hausner

Shows a representative time-activity curves of [18F]αvβ6-BP for whole blood and plasma. Data are expressed as decay-corrected percent of injected dose per gram of sample [dc %ID/g].

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc6db8d280ba490a8260fb010790a0d
https://doi.org/10.1158/1078-0432.22467615

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Preclinical Development and First-in-Human Imaging of the Integrin α

Autor: Sven H, Hausner, Richard J, Bold, Lina Y, Cheuy, Helen K, Chew, Megan E, Daly, Ryan A, Davis, Cameron C, Foster, Edward J, Kim, Julie L, Sutcliffe

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 25(4)

PURPOSE: The study was undertaken to develop and evaluate the potential of an integrin α(v)β(6)-binding peptide (α(v)β(6)-BP) for noninvasive imaging of a diverse range of malignancies with positron emission tomography (PET). EXPERIMENTAL DESIGN:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::11d91a1007e04b39dfbe9854dc1cf358
https://pubmed.ncbi.nlm.nih.gov/30401687

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