Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Lina Sui"'
Autor:
Furong Qing, Hongbo Tian, Biyao Wang, Bingyu Xie, Lina Sui, Xiaoyan Xie, Wenji He, Tiansheng He, Yumei Li, Liangmei He, Qin Guo, Zhiping Liu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Background The incidence of inflammatory bowel disease (IBD) is on the rise in developing countries, and investigating the underlying mechanisms of IBD is essential for the development of targeted therapeutic interventions. Interferon regula
Externí odkaz:
https://doaj.org/article/1e68562f83874ae8a1dcfb91b0fbbacf
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Absent in melanoma 2 (AIM2) serves as an intracellular nucleic acid sensor that predominantly detects double-stranded DNA (dsDNA) within the cells. This detection initiates the assembly of inflammasome and activates the inflammasome signaling cascade
Externí odkaz:
https://doaj.org/article/cbaa44d11aa34051a5fffe8b550240dd
Autor:
Yuwei Zhang, Lina Sui, Qian Du, Leena Haataja, Yishu Yin, Ryan Viola, Shuangyi Xu, Christian Ulrik Nielsson, Rudolph L. Leibel, Fabrizio Barbetti, Peter Arvan, Dieter Egli
Publikováno v:
Molecular Metabolism, Vol 80, Iss , Pp 101879- (2024)
Objective: Heterozygous coding sequence mutations of the INS gene are a cause of permanent neonatal diabetes (PNDM), requiring insulin therapy similar to T1D. While the negative effects on insulin processing and secretion are known, how dominant insu
Externí odkaz:
https://doaj.org/article/8fce543b22c7434f8a6ea4fc5678ee55
Autor:
Lina Sui, Junhui Li, Joshua Philp, Kai Yang, Yanli Wei, Hongmei Li, Jishun Li, Ling Li, Maarten Ryder, Ruey Toh, Yi Zhou, Matthew D. Denton, Jindong Hu, Yan Wang
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Fusarium crown rot and wheat sharp eyespot are major soil-borne diseases of wheat, causing serious losses to wheat yield in China. We applied high-throughput sequencing combined with qPCR to determine the effect of winter wheat seed dressing
Externí odkaz:
https://doaj.org/article/e5656737c1114f0fa5e8c4fae579a880
Autor:
Lina Sui, Qian Du, Anthony Romer, Qi Su, Pauline L. Chabosseau, Yurong Xin, Jinrang Kim, Sandra Kleiner, Guy A. Rutter, Dieter Egli
Publikováno v:
Cells, Vol 12, Iss 6, p 903 (2023)
The rare SLC30A8 mutation encoding a truncating p.Arg138* variant (R138X) in zinc transporter 8 (ZnT8) is associated with a 65% reduced risk for type 2 diabetes. To determine whether ZnT8 is required for beta cell development and function, we derived
Externí odkaz:
https://doaj.org/article/2e43616b294242a89cdd4004b2b2d738
Autor:
Lucas H. Armitage, Scott E. Stimpson, Katherine E. Santostefano, Lina Sui, Similoluwa Ogundare, Brittney N. Newby, Roberto Castro-Gutierrez, Mollie K. Huber, Jared P. Taylor, Prerana Sharma, Ilian A. Radichev, Daniel J. Perry, Natalie C. Fredette, Alexei Y. Savinov, Mark A. Wallet, Naohiro Terada, Todd M. Brusko, Holger A. Russ, Jing Chen, Dieter Egli, Clayton E. Mathews
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Type 1 diabetes (T1D) is a disease that arises due to complex immunogenetic mechanisms. Key cell-cell interactions involved in the pathogenesis of T1D are activation of autoreactive T cells by dendritic cells (DC), migration of T cells across endothe
Externí odkaz:
https://doaj.org/article/4cc69f69404e4a1aa049c8589a0add98
Autor:
Wei Guan, Lin Zhang, Peng Wang, Ying Wang, Haoyu Wang, Xingchen Dong, Ming Meng, Lina Sui, Zhixing Gan, Lifeng Dong, Liyan Yu
Publikováno v:
Nanomaterials, Vol 12, Iss 22, p 3980 (2022)
The introduction of impure atoms or crystal defects is a promising strategy for enhancing the photocatalytic activity of semiconductors. However, the synergy of these two effects in 2D atomic layers remains unexplored. In this case, the preparation o
Externí odkaz:
https://doaj.org/article/c67b173694244a8683063a535c23b26a
Publikováno v:
Stem Cell Reports, Vol 11, Iss 6, Pp 1407-1415 (2018)
Summary: Permanent neonatal diabetes mellitus (PNDM) can be caused by insulin mutations. We generated induced pluripotent stem cells from fibroblasts of a patient with PNDM and undetectable insulin at birth due to a homozygous mutation in the transla
Externí odkaz:
https://doaj.org/article/af2e81d2a33240988ac9a9aa09c7e288
Reduced replication fork speed promotes pancreatic endocrine differentiation and controls graft size
Autor:
Lina Sui, Yurong Xin, Qian Du, Daniela Georgieva, Giacomo Diedenhofen, Leena Haataja, Qi Su, Michael V. Zuccaro, Jinrang Kim, Jiayu Fu, Yuan Xing, Yi He, Danielle Baum, Robin S. Goland, Yong Wang, Jose Oberholzer, Fabrizio Barbetti, Peter Arvan, Sandra Kleiner, Dieter Egli
Publikováno v:
JCI Insight, Vol 6, Iss 5 (2021)
Limitations in cell proliferation are important for normal function of differentiated tissues and essential for the safety of cell replacement products made from pluripotent stem cells, which have unlimited proliferative potential. To evaluate whethe
Externí odkaz:
https://doaj.org/article/e40875517d8941f9a40856ae37cd467f
Publikováno v:
ACS Omega, Vol 2, Iss 10, Pp 6984-6990 (2017)
Externí odkaz:
https://doaj.org/article/a8b5f18118244fbbb62ab85f6c57ab38