Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Lina Siukstaite"'
Autor:
Chao Su, Marta Rodriguez-Franco, Beatrice Lace, Nils Nebel, Casandra Hernandez-Reyes, Pengbo Liang, Eija Schulze, Evgeny V. Mymrikov, Nikolas M. Gross, Julian Knerr, Hong Wang, Lina Siukstaite, Jean Keller, Cyril Libourel, Alexandra A. M. Fischer, Katharina E. Gabor, Eric Mark, Claudia Popp, Carola Hunte, Wilfried Weber, Petra Wendler, Thomas Stanislas, Pierre-Marc Delaux, Oliver Einsle, Robert Grosse, Winfried Römer, Thomas Ott
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
In plants, plasma membrane topologies are predominantly driven by the cell wall. In this study, the authors demonstrate that remorin proteins can take over these functions at specialized, unwalled plasma membranes such as infection droplets associate
Externí odkaz:
https://doaj.org/article/c0bfb6f46faf4340a3db7b4eb63fdce2
Autor:
Simona Notova, François Bonnardel, Francesca Rosato, Lina Siukstaite, Jessica Schwaiger, Jia Hui Lim, Nicolai Bovin, Annabelle Varrot, Yu Ogawa, Winfried Römer, Frédérique Lisacek, Anne Imberty
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-17 (2022)
A curated lectin database, structural characterization, and in vitro assays show that choanoflagellate lectin SaroL-1 binds to cancer-related α-galactosylated epitopes and can be toxic to cancer cells through a carbohydrate-dependent pore-formation
Externí odkaz:
https://doaj.org/article/2cc5529ab82045f7b6e6dd532ca6e260
Autor:
Simona Notova, Lina Siukstaite, Francesca Rosato, Federica Vena, Aymeric Audfray, Nicolai Bovin, Ludovic Landemarre, Winfried Römer, Anne Imberty
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 6108-6119 (2022)
Synthetic biology is a rapidly growing field with applications in biotechnology and biomedicine. Through various approaches, remarkable achievements, such as cell and tissue engineering, have been already accomplished. In synthetic glycobiology, the
Externí odkaz:
https://doaj.org/article/4c341a470d3f43dd81905c7cc5299ad1
Autor:
Dylan Jabeguero, Lina Siukstaite, Chunyue Wang, Anna Mitrovic, Serge Pérez, Olga Makshakova, Ralf P. Richter, Winfried Römer, Christelle Breton
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 335 (2023)
The present report assesses the capability of a soluble glycosyltransferase to modify glycolipids organized in two synthetic membrane systems that are attractive models to mimic cell membranes: giant unilamellar vesicles (GUVs) and supported lipid bi
Externí odkaz:
https://doaj.org/article/10c60d45d7264066b2a9bb4544634703
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Glycolipids are present on the surfaces of all living cells and thereby represent targets for many protein receptors, such as lectins. Understanding the interactions between lectins and glycolipids is essential for investigating the functions of lect
Externí odkaz:
https://doaj.org/article/dc75a8e5798f4724af3ae4b0bb7ca992
Autor:
Elisa Darkow, Eva A. Rog-Zielinska, Josef Madl, Annette Brandel, Lina Siukstaite, Ramin Omidvar, Peter Kohl, Ursula Ravens, Winfried Römer, Rémi Peyronnet
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
The healthy heart adapts continuously to a complex set of dynamically changing mechanical conditions. The mechanical environment is altered by, and contributes to, multiple cardiac diseases. Mechanical stimuli are detected and transduced by cellular
Externí odkaz:
https://doaj.org/article/f331178a8dc84d038dbf927604900d39
Autor:
Rubini Kannangara, Lina Siukstaite, Jonas Borch-Jensen, Bjørn Madsen, Kenneth T. Kongstad, Dan Staerk, Mads Bennedsen, Finn T. Okkels, Silas A. Rasmussen, Thomas O. Larsen, Rasmus J. N. Frandsen, Birger Lindberg Møller
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Carminic acid is a widely applied red colorant that is still harvested from insects because its biosynthesis is not fully understood. Here, the authors identify and characterize a membrane-bound C-glucosyltransferase catalyzing the final step during
Externí odkaz:
https://doaj.org/article/fe2382b6c1574980877761f4907a0ed4
Autor:
Lina Siukstaite, Francesca Rosato, Anna Mitrovic, Peter Fritz Müller, Katharina Kraus, Simona Notova, Anne Imberty, Winfried Römer
Publikováno v:
Toxins, Vol 13, Iss 11, p 792 (2021)
A chimeric, bispecific Janus lectin has recently been engineered with different, rationally oriented recognition sites. It can bind simultaneously to sialylated and fucosylated glycoconjugates. Because of its multivalent architecture, this lectin rea
Externí odkaz:
https://doaj.org/article/cf9540face79486296349148cedfb534
Autor:
Sarah Wehrum, W. Bruce Turnbull, Josef Madl, Maren Thomsen, Michael E. Webb, Lina Siukstaite, Gemma C. Wildsmith, James F. Ross, Daniel J. Williamson, Taras Sych, Winfried Römer, Thomas R. Branson, Wenyue Dai
Publikováno v:
ACS synthetic biology.
Membrane fusion is essential for the transport of macromolecules and viruses across membranes. While glycan-binding proteins (lectins) often initiate cellular adhesion, subsequent fusion events require additional protein machinery. No mechanism for m
Autor:
Ana Valeria Meléndez, Rubí M.-H. Velasco Cárdenas, Simon Lagies, Juliane Strietz, Lina Siukstaite, Oliver S. Thomas, Jana Tomisch, Wilfried Weber, Bernd Kammerer, Winfried Römer, Susana Minguet
Publikováno v:
Cellular and Molecular Life Sciences
The link between cancer and aberrant glycosylation has recently become evident. Glycans and their altered forms, known as tumour-associated carbohydrate antigens (TACAs), are diverse, complex and difficult to target therapeutically. Lectins are natur