Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Lina Schiffer"'
Autor:
Weiwei Xu, M.M. Fahd Qadir, Daniela Nasteska, Paula Mota de Sa, Caroline M. Gorvin, Manuel Blandino-Rosano, Charles R. Evans, Thuong Ho, Evgeniy Potapenko, Rajakrishnan Veluthakal, Fiona B. Ashford, Stavroula Bitsi, Jia Fan, Manika Bhondeley, Kejing Song, Venkata N. Sure, Siva S.V.P. Sakamuri, Lina Schiffer, Wandy Beatty, Rachael Wyatt, Daniel E. Frigo, Xiaowen Liu, Prasad V. Katakam, Wiebke Arlt, Jochen Buck, Lonny R. Levin, Tony Hu, Jay Kolls, Charles F. Burant, Alejandra Tomas, Matthew J. Merrins, Debbie C. Thurmond, Ernesto Bernal-Mizrachi, David J. Hodson, Franck Mauvais-Jarvis
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112529- (2023)
Summary: Male mice lacking the androgen receptor (AR) in pancreatic β cells exhibit blunted glucose-stimulated insulin secretion (GSIS), leading to hyperglycemia. Testosterone activates an extranuclear AR in β cells to amplify glucagon-like peptide
Externí odkaz:
https://doaj.org/article/557572b83b5a4a7ca84c9f23c0810f39
Autor:
Lina Schiffer, Punith Kempegowda, Alice J Sitch, Joanne E Adaway, Fozia Shaheen, Andreas Ebbehoj, Sumitabh Singh, Malcom P McTaggart, Michael W O’Reilly, Alessandro Prete, James M Hawley, Brian G Keevil, Irina Bancos, Angela E Taylor, Wiebke Arlt
Publikováno v:
Schiffer, L, Kempegowda, P, Sitch, A J, Adaway, J E, Shaheen, F, Ebbehoj, A, Singh, S, McTaggart, M, O'Reilly, M W, Prete, A, Hawley, J M, Keevil, B G, Bancos, I, Taylor, A E & Arlt, W 2023, ' Classic and 11-oxygenated androgens in serum and saliva across adulthood : a cross-sectional study analyzing the impact of age, body mass index, and diurnal and menstrual cycle variation ', European Journal of Endocrinology, vol. 188, no. 1 . https://doi.org/10.1093/ejendo/lvac017
Objective 11-oxygenated androgens significantly contribute to the circulating androgen pool. Understanding the physiological variation of 11-oxygenated androgens and their determinants is essential for clinical interpretation, for example, in androge
Autor:
Amarah Anthony, George Clarke, Lina Schiffer, Yiyu Fan, James Hawley, Fozia Shaheen, Angus Hann, Angela Taylor, Simon Afford, Wiebke Arlt
Publikováno v:
Endocrine Abstracts.
Autor:
Lina Schiffer, Fozia Shaheen, Lorna Gilligan, Karl Storbeck, James M Hawley, Brian Keevil, Wiebke Arlt, Angela Taylor
Publikováno v:
Endocrine Abstracts.
Autor:
Lina Schiffer, Fozia Shaheen, Lorna C. Gilligan, Karl-Heinz Storbeck, James Hawley, Brian G. Keevil, Wiebke Arlt, Angela E. Taylor
BackgroundMulti-steroid profiling is a powerful analytical tool that simultaneously quantifies steroids from different biosynthetic pathways. Here we present an ultra-high performance liquid chromatography-tandem mass spectrometry (uPLC-MS/MS) assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44f98690d2a19fcc409840f713071954
https://doi.org/10.1101/2022.03.08.22271681
https://doi.org/10.1101/2022.03.08.22271681
Autor:
Weiwei Xu, Fahd Qadir, Daniela Nasteska, Paula Mota de Sa, Caroline M. Gorvin, Manuel Blandino-Rosano, Charles R. Evans, Fiona B. Ashford, Stavroula Bitsi, Jia Fan, Manika Bhondeley, Kejing Song, Venkata N. Sure, Lina Schiffer, Wandy Beatty, Rachael Wyatt, Daniel E. Frigo, Xiaowen Liu, Prasad V. Katakam, Wiebke Arlt, Jochen Buck, Lonny R. Levin, Tony Hu, Jay Kolls, Charles F. Burant, Alejandra Tomas, Ernesto Bernal-Mizrachi, David Hodson, Franck Mauvais-Jarvis
Publikováno v:
SSRN Electronic Journal.
Autor:
Brian G. Keevil, Hongju Wu, M.M. Fahd Qadir, Yanqing Zhang, Lina Schiffer, James Hawley, Weiwei Xu, Paula Mota De Sa, Wiebke Arlt, Franck Mauvais-Jarvis
Publikováno v:
Diabetes
Testosterone (T) affects β-cell function in men and women. T is a prohormone that undergoes intracrine conversion in target tissues to the potent androgen dihydrotestosterone (DHT) via the enzyme 5α-reductase (5α-R) or to the active estrogen 17β-
Autor:
Fozia Shaheen, Wiebke Arlt, Lina Schiffer, Karl-Heinz Storbeck, James Hawley, Angela E Taylor, Brian G. Keevil, Lorna C Gilligan
Publikováno v:
Endocrine Abstracts.
Autor:
Fozia Shaheen, Lina Schiffer, James Hawley, Irina Bancos, Angela E Taylor, Punith Kempegowda, Wiebke Arlt, Andreas Ebbehoj, Alice J Sitch, Brian G. Keevil, Alessandro Prete, Sumitabh Singh, Joanne E Adaway
Publikováno v:
Endocrine Abstracts.
Autor:
Jason D. Turner, Lina Schiffer, Martin Hewison, Lorna C Gilligan, A Filer, Claire Martin, Angela E Taylor, Simon Jones, Matthew Singh Kalirai, Dagmar Scheel-Toellner, Rowan Hardy, Ana Crastin, Karim Raza, Wiebke Arlt
Publikováno v:
Endocrine Abstracts.