Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis

Autor: Fumio Nakamura, Husseini K. Manji, Namrata D. Udeshi, Hagop S. Akiskal, Jeffrey H. Price, Nikolaos Venizelos, Wen-Ning Zhao, Cordulla Duerr, Ryan W. Logan, Jeffrey S. Nye, Jasmin Lalonde, Steven D. Sheridan, Joseph T. Coyle, Toshio Ohshima, Yoshio Goshima, Michael McCarthy, Shelley Halpain, Barbara Calabrese, Joshua G. Hunsberger, Martin Alda, Yuuka Inoue, Gustavo J. Gutierrez, Stephen J. Haggarty, Brian T. D. Tobe, Cameron D. Pernia, Richard L. Sidman, Moyuka Wada, Hiroko Makihara, Laurence M. Brill, Glenn T. Konopaske, Yang Liu, De-Maw M. Chuang, Ranor C. B. Basa, Alicia M. Winquist, Yang D. Teng, Michelle M. Sidor, Steven A. Carr, Colleen A. McClung, Guy A. Rouleau, Katsuhiko Mikoshiba, Evan Y. Snyder, Laurel Dorsett, Lina Mastrangelo, Guang Chen, Jianxue Li, Haruko Nakamura, Andrew Crain, Philipp Mertins, Michael G. Brandel, Dongmei Wu, Naoya Yamashita

Publikováno v: Publikationer från Örebro universitet.

The molecular pathogenesis of bipolar disorder (BPD) is poorly understood. Using human-induced pluripotent stem cells (hiPSCs) to unravel such mechanisms in polygenic diseases is generally challenging. However, hiPSCs from BPD patients responsive to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af943d65b2b76fb0f4b555e7351a2c67
http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-57888

Contributors

Autor: Mehran Abolbashari, Jaimo Ahn, Salem Akel, Julie G. Allickson, Graça Almeida-Porada, Judith Arcidiacono, Anthony Atala, Patrick Au, Danielle Aufiero, Pedro M. Baptista, Ronnda L. Bartel, Amelia Bartholomew, Elona Baum, Angie Botto-van Bemden, Khalil N. Bitar, Lynne Boxer, Matthew P. Brown, Heather L. Brown, Stephanie J. Bryant, Pedro P. Carvalho, Prafulla Chandra, John R. Chapman, Shreyasi Das, Daniel B. Deegan, Abritee Dhal, Albert D. Donnenberg, Matthew B. Durdy, Charles N. Durfor, Elazer R. Edelman, Donald Fink, Steven Fischkoff, Joyce L. Frey-Vasconcells, Tobias Führmann, Carmen Gacchina Johnson, Or Gadish, Sanjiv S. Gambhir, Adrian P. Gee, Manuela E. Gomes, Kurt D. Hankenson, Robert J. Hariri, Heather C. Hatcher, Mohammad Heidaran, Ralf Huss, John Hyde, Yoshito Ikada, Deepak Jain, Paul A. Jain, Jesse V. Jokerst, Philipp Jungebluth, Eve Kandyba, David S. Kaplan, Safa Karandish, F. Kurtis Kasper, Sneha S. Kelkar, Norma Kenyon, Krzysztof Kobielak, Jesse Kramer, Sang Jin Lee, Mark H. Lee, Yvonne Leung, Mei Ling Lim, Neil J. Littman, Paolo Macchiarini, Nafees N. Malik, Brenda K. Mann, Kacey G. Marra, Robert E. Marx, Lina Mastrangelo, Brent McCright, Richard McFarland, Michael Mendicino, Antonios G. Mikos, Nikolaos Mitrousis, Aaron M. Mohs, Thomas Moore, Emma C. Moran, Walter Niles, Guoguang Niu, Masashi Nomi, Tamara Nunez, Robert Perry, Robert P. Pfotenhauer, Christopher D. Porada, Kavitha Premenand, Glenn D. Prestwich, Shreya Raghavan, Mahendra Rao, Anthony Ratcliffe, Stephen Rego, Rui L. Reis, Ivan N. Rich, Márcia T. Rodrigues, J. Peter Rubin, Steven Sampson, Etai Sapoznik, John G. Sharp, Molly S. Shoichet, Daniel Skuk, Evan Y. Snyder, Shay Soker, Sita Somara, Tom Spencer, Suzanne Stewart, Premenand Sundivakkam, Erszebet Szilagyi, Alexander M. Tatara, Brian Tobe, Jacques P. Tremblay, Alan O. Trounson, Anup Tuladhar, Lori Tull, Jolene E. Valentin, Dipen Vyas, Zhan Wang, Alicia Winquist, Celia Witten, Mark E.K. Wong, James J. Yoo, Diana Yoon, Elie Zakhem, Joao Paulo Zambon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f48812dff06581364be9b80ddb42f94
https://doi.org/10.1016/b978-0-12-410396-2.01002-1

Influence of storage temperature and freezing time on histamine level in the European anchovy Engraulis encrasicholus (L., 1758): A study by capillary electrophoresis

Autor: Lina Mastrangelo, Rocco Rossano, Paolo Riccio, Nicola Ungaro

Publikováno v: Journal of Chromatography B. 830:161-164

Histamine content in fish may increase by decarboxylation of free histidine to values that can be toxic, if storage conditions are not well controlled. We have studied the influence of storage temperature and time of freezing on histamine formation i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6248f00687745182d172a79dd7d644a2
https://doi.org/10.1016/j.jchromb.2005.10.026

Purinergic signaling in human pluripotent stem cells is regulated by the housekeeping gene encoding hypoxanthine guanine phosphoribosyltransferase

Autor: Tae Hyuk Kang, Atsushi Miyanohara, Lina Mastrangelo, Theodore Friedmann, Jieun Kim

Lesch–Nyhan disease (LND) is an X-linked genetic disorder caused by mutations of the hypoxanthine guanine phosphoribosyltransferase ( HPRT ) purine biosynthesis gene and characterized by aberrant purine metabolism, deficient basal ganglia dopamine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9f80dbb8b5a29487f236baf61f334f
https://europepmc.org/articles/PMC3295269/