Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lina M. Gallego-Paez"'
Autor:
Marta Martins, Luís Costa, Rita Fior, André Mansinho, Ana Lucia-Costa, Catarina Abreu, Teresa R. Pacheco, Maria J. Brito, Helder Mansinho, Ana R. Miranda, Miguel Godinho Ferreira, Ana T. Xavier, José Vílchez, João Gramaça, Daniel Machado, Lina M. Gallego-Paez, Daniel Sobral, Paula Borralho, Afonso Fernandes, Magda Negrão, Cátia Rebelo de Almeida, Raquel Cruz-Duarte
Purpose:Cetuximab is an EGFR-targeted therapy approved for the treatment of RAS wild-type (WT) metastatic colorectal cancer (mCRC). However, about 60% of these patients show innate resistance to cetuximab. To increase cetuximab efficacy, it is crucia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d133d617637977ca820648022af1b8
https://doi.org/10.1158/1078-0432.c.6531303.v1
https://doi.org/10.1158/1078-0432.c.6531303.v1
Autor:
Marta Martins, Luís Costa, Rita Fior, André Mansinho, Ana Lucia-Costa, Catarina Abreu, Teresa R. Pacheco, Maria J. Brito, Helder Mansinho, Ana R. Miranda, Miguel Godinho Ferreira, Ana T. Xavier, José Vílchez, João Gramaça, Daniel Machado, Lina M. Gallego-Paez, Daniel Sobral, Paula Borralho, Afonso Fernandes, Magda Negrão, Cátia Rebelo de Almeida, Raquel Cruz-Duarte
Supplementary Figure from Predictive and Therapeutic Implications of a Novel PLCγ1/SHP2-Driven Mechanism of Cetuximab Resistance in Metastatic Colorectal Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::083ae1169e4cc776a94303306d7877c5
https://doi.org/10.1158/1078-0432.22484019
https://doi.org/10.1158/1078-0432.22484019
Autor:
Marta Martins, Luís Costa, Rita Fior, André Mansinho, Ana Lucia-Costa, Catarina Abreu, Teresa R. Pacheco, Maria J. Brito, Helder Mansinho, Ana R. Miranda, Miguel Godinho Ferreira, Ana T. Xavier, José Vílchez, João Gramaça, Daniel Machado, Lina M. Gallego-Paez, Daniel Sobral, Paula Borralho, Afonso Fernandes, Magda Negrão, Cátia Rebelo de Almeida, Raquel Cruz-Duarte
Supplementary Data from Predictive and Therapeutic Implications of a Novel PLCγ1/SHP2-Driven Mechanism of Cetuximab Resistance in Metastatic Colorectal Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf57725dac3cb782017ff755cd50cad
https://doi.org/10.1158/1078-0432.22484034
https://doi.org/10.1158/1078-0432.22484034
Autor:
Lina M. Gallego-Paez, William J.S. Edwards, Manasa Chanduri, Yanyu Guo, Thijs Koorman, Chieh-Yu Lee, Nina Grexa, Patrick Derksen, Jie Yan, Martin A. Schwartz, Jan Mauer, Benjamin Thomas Goult
Publikováno v:
Journal of Cell Biology. 222
Talin-1 is the core mechanosensitive adapter protein linking integrins to the cytoskeleton. The TLN1 gene is comprised of 57 exons that encode the 2,541 amino acid TLN1 protein. TLN1 was previously considered to be expressed as a single isoform. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::441e8d5c0c8903959105127aee888fe9
https://doi.org/10.1083/jcb.202209010
https://doi.org/10.1083/jcb.202209010
Autor:
Raquel Cruz-Duarte, Cátia Rebelo de Almeida, Magda Negrão, Afonso Fernandes, Paula Borralho, Daniel Sobral, Lina M. Gallego-Paez, Daniel Machado, João Gramaça, José Vílchez, Ana T. Xavier, Miguel Godinho Ferreira, Ana R. Miranda, Helder Mansinho, Maria J. Brito, Teresa R. Pacheco, Catarina Abreu, Ana Lucia-Costa, André Mansinho, Rita Fior, Luís Costa, Marta Martins
Publikováno v:
Clinical Cancer Research
Clinical Cancer Research, American Association for Cancer Research, 2022, pp.clincanres.1992.2021. ⟨10.1158/1078-0432.CCR-21-1992⟩
Clinical Cancer Research, American Association for Cancer Research, 2022, pp.clincanres.1992.2021. ⟨10.1158/1078-0432.CCR-21-1992⟩
© 2022 The Authors; Published by the American Association for Cancer Research. This open access article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 International (CC BY-NC-ND)
Purpose: Cetuximab is
Purpose: Cetuximab is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a8c83eb18a02ddfbb46b4b0884da178
https://doi.org/10.1158/1078-0432.ccr-21-1992
https://doi.org/10.1158/1078-0432.ccr-21-1992
Autor:
Lina M. Gallego-Paez, William J.S. Edwards, Yanyu Guo, Manasa Chanduri, Thijs Koorman, Chieh-Yu Lee, Nina Grexa, Patrick W. B. Derksen, Jie Yan, Martin A. Schwartz, Jan Mauer, Benjamin T. Goult
Talin 1 is the core mechanosensitive adapter protein linking integrins to the cytoskeleton. The TLN1 gene is comprised of 57 exons that encode the 2541 amino acid TLN1 protein. TLN1 was previously considered to be expressed as a single isoform. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5760f0a706abc619396f43b4c906889
https://doi.org/10.1101/2022.09.06.506802
https://doi.org/10.1101/2022.09.06.506802
Publikováno v:
eLS
Accurate chromosome segregation during both mitosis and meiosis is governed by an intricate and synchronised cascade of events. These are controlled by the molecular networks that ensure the proper assembly of sister deoxyribonucleic acid (DNA) molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb5759496e00c9cb6f71f4bef8d504c4
https://doi.org/10.1002/9780470015902.a0005917.pub2
https://doi.org/10.1002/9780470015902.a0005917.pub2