Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Lina Leiss"'
Autor:
Tatjana Wallmann, Xing-Mei Zhang, Majken Wallerius, Sara Bolin, Anne-Laure Joly, Caroline Sobocki, Lina Leiss, Yiwen Jiang, Jonas Bergh, Eric C. Holland, Per Ø. Enger, John Andersson, Fredrik J. Swartling, Hrvoje Miletic, Lene Uhrbom, Robert A. Harris, Charlotte Rolny
Publikováno v:
iScience, Vol 9, Iss , Pp 71-83 (2018)
Summary: High-grade gliomas (HGGs) are the most aggressive and invasive primary brain tumors. The platelet-derived growth factor (PDGF) signaling pathway drives HGG progression, and enhanced expression of PDGF receptors (PDGFRs) is a well-established
Externí odkaz:
https://doaj.org/article/8c34cad0c73543d2be8db8d7c916df08
Publikováno v:
Biomarkers of the Tumor Microenvironment ISBN: 9783030989491
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17cca67b3401b789d76ac624fdb41282
https://doi.org/10.1007/978-3-030-98950-7_30
https://doi.org/10.1007/978-3-030-98950-7_30
Autor:
Hrvoje Miletic, Lina Leiss, Caroline Sobocki, Robert A. Harris, Per Øyvind Enger, Yiwen Jiang, Fredrik J. Swartling, Jonas Bergh, Charlotte Rolny, Xing-Mei Zhang, Tatjana Wallmann, Eric C. Holland, Lene Uhrbom, John Andersson, Majken Wallerius, Anne-Laure Joly, Sara Bolin
Publikováno v:
iScience, Vol 9, Iss, Pp 71-83 (2018)
iScience
iScience
Summary High-grade gliomas (HGGs) are the most aggressive and invasive primary brain tumors. The platelet-derived growth factor (PDGF) signaling pathway drives HGG progression, and enhanced expression of PDGF receptors (PDGFRs) is a well-established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::638eeaa577797035d172a8cff207a467
https://doi.org/10.1016/j.isci.2018.10.011
https://doi.org/10.1016/j.isci.2018.10.011
Autor:
Linda Sleire, Inger Anne Netland, Per Øyvind Enger, Bente Sandvei Skeie, Hilde Elise Førde, Lina Leiss
Publikováno v:
Pharmacological Research. 124:74-91
Cancer is a major health issue worldwide, and the global burden of cancer is expected to increase in the coming years. Whereas the limited success with current therapies has driven huge investments into drug development, the average number of FDA app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb060af8e79221f560a528fb79c9dc6e
https://doi.org/10.1016/j.phrs.2017.07.013
https://doi.org/10.1016/j.phrs.2017.07.013
Autor:
Inger Anne Netland, Linda Sleire, B. S. Skeie, Dorota Goplen, Hrvoje Miletic, Lina Leiss, Hilde Elise Førde, Mohummad Aminur Rahman, Per Øyvind Enger
Publikováno v:
Journal of Neuro-Oncology
Glioblastomas (GBMs) are aggressive brain tumours with a dismal prognosis, despite combined surgery, radio- and chemotherapy. Close to 90 % of all GBMs harbour a deregulated PI3K pathway, which is essential in regulating central cellular functions su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bd15f8c9d6f6a835f2588f3adce75cd
http://europepmc.org/articles/PMC4972854
http://europepmc.org/articles/PMC4972854
Glioblastoma is a highly heterogeneous disease, characterized by high invasion, florid angiogenesis and poor prognosis. Data from recent years introduces the microenvironmental involvement in glioma biology. Still the involvement of astrocytes in Gli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c376128320798e2d514b4caa9cdc5593
https://europepmc.org/articles/PMC5692080/
https://europepmc.org/articles/PMC5692080/
Publikováno v:
Experimental cell research. 359(1)
Background Epithelial to mesenchymal transition (EMT) is considered to be important for cancer invasion and metastasis. Tumour hypoxia, in addition to Transforming Growth Factor-β (TGF-β) and Notch, amongst others, have been suggested to be involve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4fa025d99079b505189cb32b995f84
https://pubmed.ncbi.nlm.nih.gov/28734865
https://pubmed.ncbi.nlm.nih.gov/28734865
Autor:
Anne Margrete Øyan, Ercan Mutlu, Jian Wang, Oleg Tsinkalovsky, Linda Sleire, Xingang Li, Nicolas H.C. Brons, Tao Yan, Mireille Kayitesi Johannessen, Kjell Petersen, Siddharta S. Mitra, Hege Karine Jacobsen, Krishna M. Talasila, Mohummad Aminur Rahman, Hrvoje Miletic, Lina Leiss, Per Øyvind Enger, Karl-Henning Kalland, Inge Jonassen
Publikováno v:
BMC Cancer
Background Little is known about the role of glial host cells in brain tumours. However, supporting stromal cells have been shown to foster tumour growth in other cancers. Methods We isolated stromal cells from patient-derived glioblastoma (GBM) xeno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13854031e5332508e10433f3ff7ed02f
https://hdl.handle.net/1956/17440
https://hdl.handle.net/1956/17440
Publikováno v:
Biomarkers of the Tumor Microenvironment ISBN: 9783319391458
Malignant gliomas are infiltrative tumors arising in the brain, characterized by degradation of the extracellular matrix and tumor cell migration along white matter tracts. The most aggressive form displays florid angiogenesis and recruitment of host
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba45ebdfe70cc2678e6c0619e9e79cbf
https://doi.org/10.1007/978-3-319-39147-2_20
https://doi.org/10.1007/978-3-319-39147-2_20
Autor:
Per Øyvind Enger, Inger Anne Netland, Linda Sleire, Dorota Goplen, B. S. Skeie, Hilde Elise Førde, Christiane H. Gjerde, Mohummad Aminur Rahman, Lina Leiss
Publikováno v:
BMC Cancer
Background: Glioblastomas (GBMs) are highly malignant brain tumours with a poor prognosis, and current cytotoxic regimens provide only a limited survival benefit. The PI3K/Akt/mTOR pathway has been an attractive target for therapy due to its high act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73cd2047d10c1d82294c119a270cfc3b
https://hdl.handle.net/1956/12918
https://hdl.handle.net/1956/12918