Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Lina Jonsson"'
Autor:
Ying Xiong, Robert Karlsson, Jie Song, Kaarina Kowalec, Christian Rück, Robert Sigström, Lina Jonsson, Caitlin C. Clements, Evelyn Andersson, Julia Boberg, Cathryn M. Lewis, Patrick F. Sullivan, Mikael Landén, Yi Lu
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-7 (2023)
Abstract Treatment response and resistance in major depressive disorder (MDD) are suggested to be heritable. Due to significant challenges in defining treatment-related phenotypes, our understanding of their genetic bases is limited. This study aimed
Externí odkaz:
https://doaj.org/article/4e43f3a03d394c78baab245c5bdf8dde
Therapeutic Effect of Nicotinamide Mononucleotide for Hypoxic–Ischemic Brain Injury in Neonatal Mice
Autor:
Takuya Kawamura, Gagandeep Singh Mallah, Maryam Ardalan, Tetyana Chumak, Pernilla Svedin, Lina Jonsson, Seyedeh Marziyeh Jabbari Shiadeh, Fanny Goretta, Tomoaki Ikeda, Henrik Hagberg, Mats Sandberg, Carina Mallard
Publikováno v:
ASN Neuro, Vol 15 (2023)
A clinical challenge remains in the treatment of hypoxic–ischemic brain injury in newborns. Nicotinamide adenine dinucleotide (NAD + ) has beneficial effects in animal models of adult stroke. Here, we aimed to understand the short- and long-term ne
Externí odkaz:
https://doaj.org/article/b0ce2f7a267f4400b808330c8df39e82
Autor:
Lina Jonsson, Joanna Martin, Paul Lichtenstein, Patrik K. E. Magnusson, Sebastian Lundström, Lars Westberg, Kristiina Tammimies
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 11, Iss 8, Pp n/a-n/a (2023)
Abstract Background Several copy number variations (CNVs) are associated with increased risk for neurodevelopmental and psychiatric disorders. The CNV 15q11.2 (BP1‐BP2) deletion has been associated with learning difficulties, attention deficit hype
Externí odkaz:
https://doaj.org/article/8aa53fdbe4b74a60834266c1e954804e
Autor:
G. Bragi Walters, Omar Gustafsson, Gardar Sveinbjornsson, Valgerdur K. Eiriksdottir, Arna B. Agustsdottir, Gudrun A. Jonsdottir, Stacy Steinberg, Arni F. Gunnarsson, Magnus I. Magnusson, Unnur Unnsteinsdottir, Amy L. Lee, Adalbjorg Jonasdottir, Asgeir Sigurdsson, Aslaug Jonasdottir, Astros Skuladottir, Lina Jonsson, Muhammad S. Nawaz, Patrick Sulem, Mike Frigge, Andres Ingason, Askell Love, Gudmundur L. Norddhal, Mark Zervas, Daniel F. Gudbjartsson, Magnus O. Ulfarsson, Evald Saemundsen, Hreinn Stefansson, Kari Stefansson
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Intellectual disability (ID) is characterized by an intelligence quotient of below 70 and impaired adaptive skills. Here, analyzing whole genome sequences from 31,463 Icelanders, Walters et al. identify variants in MAP1B associated with ID and extens
Externí odkaz:
https://doaj.org/article/d70b7d7d8ac24f859136afd1d51a5234
Publikováno v:
Journal of Affective Disorders. 324:449-454
Bipolar disorder is a severe psychiatric syndrome defined by periodic mood shifts. Patients with bipolar disorder show cognitive impairments relative to healthy controls. The risk of developing schizophrenia, and partially also bipolar disorder, has
Autor:
Erik Joas, Lina Jonsson, Alexander Viktorin, Erik Smedler, Erik Pålsson, Guy M. Goodwin, Mikael Landén
Publikováno v:
The Pharmacogenomics Journal. 23:28-35
Antidepressant medication is used extensively to treat bipolar depression despite uncertain efficacy. The cytochrome P450 (CYP) 2C19 enzyme metabolize several antidepressants, and polymorphisms in the corresponding gene CYP2C19 influence plasma conce
Autor:
Robert Sigström, Kaarina Kowalec, Lina Jonsson, Caitlin C. Clements, Robert Karlsson, Axel Nordenskjöld, Erik Pålsson, Patrick F. Sullivan, Mikael Landén
Publikováno v:
American Journal of Psychiatry. 179:844-852
Autor:
Lina Jonsson, Joanna Martin, Paul Lichtenstein, Patrik K. E. Magnusson, Sebastian Lundström, Lars Westberg, Kristiina Tammimies
Publikováno v:
Molecular Genetics & Genomic Medicine.
Autor:
Duncan S. Palmer, Daniel P. Howrigan, Sinéad B. Chapman, Rolf Adolfsson, Nick Bass, Douglas Blackwood, Marco P. M. Boks, Chia-Yen Chen, Claire Churchhouse, Aiden P. Corvin, Nicholas Craddock, David Curtis, Arianna Di Florio, Faith Dickerson, Nelson B. Freimer, Fernando S. Goes, Xiaoming Jia, Ian Jones, Lisa Jones, Lina Jonsson, Rene S. Kahn, Mikael Landén, Adam E. Locke, Andrew M. McIntosh, Andrew McQuillin, Derek W. Morris, Michael C. O’Donovan, Roel A. Ophoff, Michael J. Owen, Nancy L. Pedersen, Danielle Posthuma, Andreas Reif, Neil Risch, Catherine Schaefer, Laura Scott, Tarjinder Singh, Jordan W. Smoller, Matthew Solomonson, David St. Clair, Eli A. Stahl, Annabel Vreeker, James T. R. Walters, Weiqing Wang, Nicholas A. Watts, Robert Yolken, Peter P. Zandi, Benjamin M. Neale
Publikováno v:
Nature genetics, 54(5), 541-547. Nature Publishing Group
Nature genetics, vol 54, iss 5
Nature Genetics, 54(5), 541-547. Nature Publishing Group
Palmer, D S, Howrigan, D P, Chapman, S B, Adolfsson, R, Bass, N, Blackwood, D, Boks, M P M, Chen, C-Y, Churchhouse, C, Corvin, A P, Craddock, N, Curtis, D, di Florio, A, Dickerson, F, Freimer, N B, Goes, F S, Jia, X, Jones, I, Jones, L, Jonsson, L, Kahn, R S, Landén, M, Locke, A E, McIntosh, A M, McQuillin, A, Morris, D W, O’Donovan, M C, Ophoff, R A, Owen, M J, Pedersen, N L, Posthuma, D, Reif, A, Risch, N, Schaefer, C, Scott, L, Singh, T, Smoller, J W, Solomonson, M, Clair, D S, Stahl, E A, Vreeker, A, Walters, J T R, Wang, W, Watts, N A, Yolken, R, Zandi, P P & Neale, B M 2022, ' Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia ', Nature Genetics, vol. 54, no. 5, pp. 541-547 . https://doi.org/10.1038/s41588-022-01034-x
Nat Genet
Palmer, D S, Howrigan, D P, Chapman, S B, Adolfsson, R, Bass, N, Blackwood, D, Boks, M P M, Chen, C Y, Churchhouse, C, Corvin, A P, Craddock, N, Curtis, D, Di Florio, A, Dickerson, F, Freimer, N B, Goes, F S, Jia, X, Jones, I, Jones, L, Jonsson, L, Kahn, R S, Landén, M, Locke, A E, McIntosh, A M, McQuillin, A, Morris, D W, O’Donovan, M C, Ophoff, R A, Owen, M J, Pedersen, N L, Posthuma, D, Reif, A, Risch, N, Schaefer, C, Scott, L, Singh, T, Smoller, J W, Solomonson, M, Clair, D S, Stahl, E A, Vreeker, A, Walters, J T R, Wang, W, Watts, N A, Yolken, R, Zandi, P P & Neale, B M 2022, ' Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia ', Nature genetics, vol. 54, no. 5, pp. 541-547 . https://doi.org/10.1038/s41588-022-01034-x
Nature genetics, vol 54, iss 5
Nature Genetics, 54(5), 541-547. Nature Publishing Group
Palmer, D S, Howrigan, D P, Chapman, S B, Adolfsson, R, Bass, N, Blackwood, D, Boks, M P M, Chen, C-Y, Churchhouse, C, Corvin, A P, Craddock, N, Curtis, D, di Florio, A, Dickerson, F, Freimer, N B, Goes, F S, Jia, X, Jones, I, Jones, L, Jonsson, L, Kahn, R S, Landén, M, Locke, A E, McIntosh, A M, McQuillin, A, Morris, D W, O’Donovan, M C, Ophoff, R A, Owen, M J, Pedersen, N L, Posthuma, D, Reif, A, Risch, N, Schaefer, C, Scott, L, Singh, T, Smoller, J W, Solomonson, M, Clair, D S, Stahl, E A, Vreeker, A, Walters, J T R, Wang, W, Watts, N A, Yolken, R, Zandi, P P & Neale, B M 2022, ' Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia ', Nature Genetics, vol. 54, no. 5, pp. 541-547 . https://doi.org/10.1038/s41588-022-01034-x
Nat Genet
Palmer, D S, Howrigan, D P, Chapman, S B, Adolfsson, R, Bass, N, Blackwood, D, Boks, M P M, Chen, C Y, Churchhouse, C, Corvin, A P, Craddock, N, Curtis, D, Di Florio, A, Dickerson, F, Freimer, N B, Goes, F S, Jia, X, Jones, I, Jones, L, Jonsson, L, Kahn, R S, Landén, M, Locke, A E, McIntosh, A M, McQuillin, A, Morris, D W, O’Donovan, M C, Ophoff, R A, Owen, M J, Pedersen, N L, Posthuma, D, Reif, A, Risch, N, Schaefer, C, Scott, L, Singh, T, Smoller, J W, Solomonson, M, Clair, D S, Stahl, E A, Vreeker, A, Walters, J T R, Wang, W, Watts, N A, Yolken, R, Zandi, P P & Neale, B M 2022, ' Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia ', Nature genetics, vol. 54, no. 5, pp. 541-547 . https://doi.org/10.1038/s41588-022-01034-x
We report results from the Bipolar Exome (BipEx) collaboration analysis of whole-exome sequencing of 13,933 patients with bipolar disorder (BD) matched with 14,422 controls. We find an excess of ultra-rare protein-truncating variants (PTVs) in patien
Autor:
Yi Lu, Ying Xiong, Robert Karlsson, Jie Song, Kaarina Kowalec, Christian Rück, Robert Sigstrom, Lina Jonsson, Caitlin Clements, Evelyn Andersson, Julia Boberg, Cathryn Lewis, Patrick Sullivan, Mikael Landén
Treatment response and resistance in major depressive disorder (MDD) are suggested to be heritable. Due to significant challenges in defining treatment-related phenotypes, our understanding of their genetic bases is limited. This study aimed to deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c38f9307ba322ec687f903f595dd990
https://doi.org/10.21203/rs.3.rs-2556941/v1
https://doi.org/10.21203/rs.3.rs-2556941/v1