Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lina Darwish"'
Autor:
Benjamin M. Grant, Aein Zarrin, Luna Zhan, Rami Ajaj, Lina Darwish, Khaleeq Khan, Devalben Patel, Kaitlyn Chiasson, Karmugi Balaratnam, Maisha T. Chowdhury, Amir-Arsalan Sabouhanian, Joshua Herman, Preet Walia, Evan Strom, Catherine Brown, Miguel Garcia-Pardo, Sabine Schmid, Christopher Pettengell, Erin L. Stewart, Geoffrey Liu
Publikováno v:
Cancer Research. 82:4087-4087
Background: The widespread uptake of electronic health records (EHRs) has made the creation of custom, real-world datasets for research more feasible. As a result, multiple research datasets with overlapping populations are often generated, using dif
Publikováno v:
Journal of the Endocrine Society
Osteocalcin is a protein produced in the osteoblasts of bone and found both in the bone matrix and in circulation1. Mouse studies have demonstrated that osteocalcin administration improves type II diabetes through increased insulin release and sensit
Autor:
Lina Darwish, Sophie K. Wong, Michelle M. Nguyen, Chelsi Major-Orfao, Nathan Herrmann, Kim S. Sugamori, Walter Swardfager, Pearl Yang, Krista L. Lanctôt, Jessica Colby-Milley, Ilana Halperin, Paul Oh, Baiju R. Shah, Jane Mitchell, Jeremy Gilbert, Angela Assal
Publikováno v:
Journal of the Endocrine Society
Serum osteocalcin is emerging as a potential marker of glucose homeostasis and risk of type 2 diabetes mellitus (T2DM). In mice, osteocalcin knockouts exhibit depressive-like behaviours but knockouts of a putative osteocalcin receptor, GPR158, are re
Autor:
Joel C. Watts, Maximilian Strauss, Sarah J. Colpitts, Russell Luke, Ahmad R. Israwi, Marc Shenouda, Saffire H. Krance, Lina Darwish
Publikováno v:
Journal of neurochemistryREFERENCES. 153(2)
Prions, which cause fatal neurodegenerative disorders such as Creutzfeldt-Jakob disease, are misfolded and infectious protein aggregates. Currently, there are no treatments available to halt or even delay the progression of prion disease in the brain
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
Type 2 diabetes mellitus (T2DM) is associated with depressive symptoms, and comorbid depression in those with T2DM has been associated with adverse clinical profiles. Recognizing and addressing psychological symptoms remain significant clinical chall
Autor:
Chelsi Major-Orfao, Michelle M. Nguyen, Nathan Herrmann, Lina Darwish, Angela Assal, Sophie K. Wong, Krista L. Lanctôt, Walter Swardfager, Pearl Yang, Paul Oh, Jessica Colby-Milley, Ilana Halperin, Jane Mitchell, Baiju R. Shah, Jeremy Gilbert, Kim S. Sugamori
Publikováno v:
Biological Psychiatry. 87:S437-S438
Autor:
Lina Darwish, Paul Oh, Kim S. Sugamori, M.M. Nguyen, K.A. Eakin, Nathan Herrmann, Krista L. Lanctôt, Jane Mitchell, P. Yang, Mahwesh Saleem, Walter Swardfager
Publikováno v:
Journal of diabetes and its complications. 33(5)
Background Lower serum concentrations of the osteoblast-derived protein, osteocalcin, have been associated with poorer glycemic control, insulin resistance and atherosclerosis, and with the development of type 2 diabetes (T2DM). Methods This study co