Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lina Alhalhooly"'
Autor:
Jessica Pullan, Kaitlin Dailey, Sangeeta Bhallamudi, Li Feng, Lina Alhalhooly, Jamie Froberg, Jenna Osborn, Kausik Sarkar, Todd Molden, Venkatachalem Sathish, Yongki Choi, Amanda Brooks, Sanku Mallik
Publikováno v:
ACS Appl Bio Mater
Biological nanoparticles, such as exosomes, offer an approach to drug delivery due to their innate ability to transport biomolecules. Exosomes are derived from cells and an integral component of cellular communication. However, the cellular cargo of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fcf9f3789b7e3ffb1178b4f1263df80
https://doi.org/10.1021/acsabm.2c00015
https://doi.org/10.1021/acsabm.2c00015
Autor:
Lina Alhalhooly, Matthew I. Confeld, Sung Oh Woo, Babak Mamnoon, Reed Jacobson, Shrinwanti Ghosh, Jiha Kim, Sanku Mallik, Yongki Choi
Publikováno v:
ACS Appl Mater Interfaces
Integrin targeting, arginine-glycine-aspartic acid (RGD)-based nanocarriers have been widely used for tumor imaging, the monitoring of tumor development, and the delivery of anti-cancer drugs. However, the thermodynamics of an RGD-integrin formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c283f217236a30c04671eee82c60eaf7
https://doi.org/10.1021/acsami.1c23361
https://doi.org/10.1021/acsami.1c23361
Publikováno v:
Oncotarget
The changes in cellular structure play an important role in cancer cell development, progression, and metastasis. By exploiting single-cell, force spectroscopy methods, we probed biophysical and biomechanical kinetics (stiffness, morphology, roughnes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4232b6296d115a84e6b599fd0077c957
https://doi.org/10.18632/oncotarget.27974
https://doi.org/10.18632/oncotarget.27974
Different Single-Enzyme Conformational Dynamics upon Binding Hydrolyzable or Nonhydrolyzable Ligands
Autor:
Arith J. Rajapakse, Myungkeun Oh, Sung Oh Woo, Jasmin Farmakes, Philip G. Collins, Zhongyu Yang, Yongki Choi, Lina Alhalhooly
Publikováno v:
The journal of physical chemistry. B, vol 125, iss 22
J Phys Chem B
J Phys Chem B
Single-molecule measurements of protein dynamics help unveil the complex conformational changes and transitions that occur during ligand binding and catalytic processes. Using high-resolution single-molecule nanocircuit techniques, we have investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e3e225b48cdaa5aa084e5fdef042c8
https://doi.org/10.1021/acs.jpcb.1c01589
https://doi.org/10.1021/acs.jpcb.1c01589
Autor:
Vikneshwari Natarajan, Alexander Delgado, Reed Jacobson, Lina Alhalhooly, Yongki Choi, Sangdeuk Ha, Jiha Kim
Publikováno v:
Cancer Research. 82:LB053-LB053
Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer death in men and women in the U.S., with a 5-year survival rate of 10%. This poor prognosis is partly due to the aggressive nature of the disease, lack of early detection m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68a40940a325f0a11e81b1afd5e1b3d9
https://doi.org/10.1158/1538-7445.am2022-lb053
https://doi.org/10.1158/1538-7445.am2022-lb053
Autor:
Mohiuddin A. Quadir, Arnab Ghosh, Sushanta K. Banerjee, Sanku Mallik, Priyanka Ray, Lina Alhalhooly, Yongki Choi, Snigdha Banerjee
Publikováno v:
ACS biomaterials scienceengineering. 5(3)
Hyperbranched polymer-derived drug nanocarriers have been synthesized that can change sizes selectively in response to pH. These constructs were composed of tertiary amine-conjugated polycarbonate blocks "grafted from" a hyperbranched polyester polyo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0241d7892a8d9689063e247e92b8f31
https://pubmed.ncbi.nlm.nih.gov/33405653
https://pubmed.ncbi.nlm.nih.gov/33405653
Autor:
Zhongyu Yang, Yanxiong Pan, Lina Alhalhooly, Qiaobin Li, Bingcan Chen, Yue Li, Yongki Choi, Hui Li
Publikováno v:
ACS Appl Mater Interfaces
Immobilizing enzymes on nanoparticles (NPs) enhances the cost-efficiency of biocatalysis; however, when the substrates are large, it becomes difficult to separate the enzyme@NP from the products while avoiding leaching or damage of enzymes in the rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77baa02b7fae1273bdb5af423c22ad36
https://pubmed.ncbi.nlm.nih.gov/32830486
https://pubmed.ncbi.nlm.nih.gov/32830486
Autor:
Qiaobin Li, Zhongyu Yang, Yanxiong Pan, Yongki Choi, Isabelle Schuster, Jasmin Farmakes, Amanda Overby, Angel Ugrinov, Mary Lenertz, Lina Alhalhooly
Publikováno v:
ACS applied materialsinterfaces. 12(20)
Although enzyme immobilization has improved many areas, biocatalysis involving large-size substrates is still challenging for immobilization platform design because of the protein damage under the often "harsh" reaction conditions required for these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2666dd2def47feb4f764ac666df3273b
https://pubmed.ncbi.nlm.nih.gov/32338863
https://pubmed.ncbi.nlm.nih.gov/32338863
Publikováno v:
Biophysical Journal. 118:467a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90e1948c494b7982188dd681471bb5af
https://doi.org/10.1016/j.bpj.2019.11.2593
https://doi.org/10.1016/j.bpj.2019.11.2593