Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lina A, Grinevich"'
Autor:
Marharyta M. Suleiman, Andrii I. Fedosov, Ranjan K. Mohapatra, Irina A. Sych, Lina O. Grinevich, Nataliia P. Kobzar, Vitaliy D. Yaremenko, Lina O. Perekhoda
Publikováno v:
Журнал органічної та фармацевтичної хімії, Vol 21, Iss 1, Pp 54-60 (2023)
Aim. Using in silico technologies to search for potential SARS-CoV-2 inhibitors among novel tetracyclic ring systems, which are the common core of Crinipellin. Materials and methods. The study object was new compounds previously synthesized via oxid
Externí odkaz:
https://doaj.org/article/4fcd6c5a918f4f858600d6d7d1332614
Autor:
Igor V. Ukrainets, Lidiya A. Petrushova, Svitlana V. Shishkina, Lina A. Grinevich, Galina Sim
Publikováno v:
Scientia Pharmaceutica, Vol 84, Iss 4, Pp 705-714 (2016)
In order to obtain and then test pharmocologically any possible conformers of the new feasible analgesic N-benzyl-4-hydroxy-1-methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxamide, its 4-O-sodium salt was synthesized using two methods. X-ray diffrac
Externí odkaz:
https://doaj.org/article/897c84164b3a48feb96bef9ab2f43043
Autor:
Igor V. Ukrainets, Ganna M. Hamza, Anna A. Burian, Natali I. Voloshchuk, Oxana V. Malchenko, Svitlana V. Shishkina, Lina A. Grinevich, Vasyl V. Grynenko, Galina Sim
Publikováno v:
Scientia Pharmaceutica, Vol 86, Iss 4, p 50 (2018)
The analysis of our previous studies on the search for synthetic analgesics among N-R-amides of bicyclic hetaryl-3-carboxylic acids has been performed; on its basis N-hetaryl(aryl)-alkyl-4-methyl-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxamides have
Externí odkaz:
https://doaj.org/article/7e25eb729712445a907600312c1a7b5e
Autor:
Igor V. Ukrainets, Mykola Y. Golik, Lyudmila V. Sidorenko, Valentina I. Korniyenko, Lina A. Grinevich, Galina Sim, Olga V. Kryvanych
Publikováno v:
Scientia Pharmaceutica, Vol 86, Iss 3, p 31 (2018)
In accordance with the principles of “me-too” technique, the preparative method for obtaining has been proposed, and the synthesis of a large series of new N-(arylalkyl)-6-hydroxy-2-methyl-4-oxo-2,4-dihydro-1H-pyrrolo[3,2,1-ij]quinoline-5-carboxa
Externí odkaz:
https://doaj.org/article/16d87faa18e940aaa6d30e050aa38dca
Autor:
Igor V. Ukrainets, Lyudmila V. Sidorenko, Mykola Y. Golik, Igor M. Chernenok, Lina A. Grinevich, Alexandra A. Davidenko
Publikováno v:
Scientia Pharmaceutica, Vol 86, Iss 2, p 12 (2018)
Continuing a targeted search for new leading structures with diuretic action among tricyclic derivatives of hydroxyquinolines, which are of interest as potential inhibitors of aldosterone synthase, the synthesis of a series of the corresponding pyrid
Externí odkaz:
https://doaj.org/article/47de1e988c544d979d47f23d1b54b757
Autor:
Svetlana V. Shishkina, Oleg V. Shishkin, Igor V. Ukrainets, Andrei A. Tkach, Lina A. Grinevich
Publikováno v:
Acta Crystallographica Section E, Vol 65, Iss 8, Pp o1984-o1984 (2009)
The asymmetric unit of the title compound, 4C20H22N4O5·2C2H6O·CH4O, contains two pyridine-3-carboxylate molecules, one ethanol molecule and one methanol molecule disordered about in a centre of symmetry. The pyridinone ring, the carbamide group and
Externí odkaz:
https://doaj.org/article/851c5bbe1eb740bfb3463efdc212fd61
Publikováno v:
Scientia Pharmaceutica
A new, effective preparative method has been proposed and the synthesis of a series of N-(arylalkyl)-1-R-4-hydroxy-2,2-dioxo-1H-2λ(6),1-benzothiazine-3-car-boxamides has been carried out. It has been shown that amidation of alkyl 1-R-4-hydroxy-2,2-d