Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Lina, Prasmickaite"'
Autor:
Salim Ghannoum, Damiano Fantini, Muhammad Zahoor, Veronika Reiterer, Santosh Phuyal, Waldir Leoncio Netto, Øystein Sørensen, Arvind Iyer, Debarka Sengupta, Lina Prasmickaite, Gunhild Mari Mælandsmo, Alvaro Köhn-Luque, Hesso Farhan
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 4, p e1010995 (2023)
Our understanding of how speed and persistence of cell migration affects the growth rate and size of tumors remains incomplete. To address this, we developed a mathematical model wherein cells migrate in two-dimensional space, divide, die or intravas
Externí odkaz:
https://doaj.org/article/b8118049e62a414e937e60e0e8721f71
Autor:
Marta Nyakas, Karianne Giller Fleten, Mads Haugland Haugen, Nikolai Engedal, Christina Sveen, Inger Nina Farstad, Vivi Ann Flørenes, Lina Prasmickaite, Gunhild Mari Mælandsmo, Kotryna Seip
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract More than half of metastatic melanoma patients receiving standard therapy fail to achieve a long-term survival due to primary and/or acquired resistance. Tumor cell ability to switch from epithelial to a more aggressive mesenchymal phenotype
Externí odkaz:
https://doaj.org/article/9ed4fda92ae4471a8ea70e8ac8bab465
Autor:
Solveig Pettersen, Geir Frode Øy, Eivind Valen Egeland, Siri Juell, Olav Engebråten, Gunhild Mari Mælandsmo, Lina Prasmickaite
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Assessment of drug sensitivity in tumor tissue ex vivo may significantly contribute to functional diagnostics to guide personalized treatment of cancer. Tumor organoid- and explant-cultures have become attractive tools towards this goal, although cul
Externí odkaz:
https://doaj.org/article/6ce42576d2d34e0387fa3dbd48539e9c
Autor:
Anna Barkovskaya, Craig M. Goodwin, Kotryna Seip, Bylgja Hilmarsdottir, Solveig Pettersen, Clint Stalnecker, Olav Engebraaten, Eirikur Briem, Channing J. Der, Siver A. Moestue, Thorarinn Gudjonsson, Gunhild M. Mælandsmo, Lina Prasmickaite
Publikováno v:
Molecular Oncology, Vol 15, Iss 8, Pp 2026-2045 (2021)
Cellular phenotype plasticity between the epithelial and mesenchymal states has been linked to metastasis and heterogeneous responses to cancer therapy, and remains a challenge for the treatment of triple‐negative breast cancer (TNBC). Here, we use
Externí odkaz:
https://doaj.org/article/0cf47b80942b4dccb4f54632467c29f1
Autor:
Lina Prasmickaite, Ellen M. Tenstad, Solveig Pettersen, Shakila Jabeen, Eivind V. Egeland, Silje Nord, Abhilash Pandya, Mads H. Haugen, Vessela N. Kristensen, Anne‐Lise Børresen‐Dale, Oslo Breast Cancer Research Consortium (OSBREAC), Olav Engebråten, Gunhild M. Mælandsmo
Publikováno v:
Molecular Oncology, Vol 12, Iss 9, Pp 1540-1558 (2018)
The tumor microenvironment (TME) may influence both cancer progression and therapeutic response. In breast cancer, particularly in the aggressive triple‐negative/basal‐like subgroup, patient outcome is strongly associated with the tumor's inflamm
Externí odkaz:
https://doaj.org/article/382c45859b2945768f322dd7ece1396d
Autor:
Maria Aanesland Dahle, Eivind Valen Egeland, Lina Prasmickaite, Ole Christian Lingjærde, Hege Russnes, Øystein Garred, Marianne L. Smebye, Helle Skjerven, Ellen Schlichting, Bjørn Naume, Gunhild Mælandsmo, Olav Engebraaten, Mads H. Haugen
Publikováno v:
Cancer Research. 83:2170-2170
Background and Purpose: Neoadjuvant treatment regimens containing the DNA-targeting chemotherapy carboplatin has been shown to increase the pathological complete response (pCR) rate in triple negative (TN) breast cancer. In addition, the response to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba8dc9e6ee17fcaf880f0da6353b13e9
https://doi.org/10.1158/1538-7445.am2023-2170
https://doi.org/10.1158/1538-7445.am2023-2170
Autor:
Eivind Valen Egeland, Kotryna Seip, Geir Frode Øy, Eleni Skourti, Solveig J Pettersen, Siri Juell, Mads Haugland Haugen, Olav Engebraaten, Lina Prasmickaite, Gunhild M Maelandsmo
Publikováno v:
Cancer Research. 83:4675-4675
Resistance to chemotherapy is a major clinical challenge in breast cancer (BC), and patients developing resistance need treatment alternatives. In this project we utilize patient-derived xenografts (PDXs) from triple negative BC (TNBC), as these mode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24c3711cecad2e1cd3b3ca1ffb686dc0
https://doi.org/10.1158/1538-7445.am2023-4675
https://doi.org/10.1158/1538-7445.am2023-4675
Autor:
Lina Prasmickaite, Harri M. Itkonen, Ian G. Mills, Anna Barkovskaya, Kotryna Seip, Siver Andreas Moestue
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Barkovskaya, A, Seip, K, Prasmickaite, L, Mills, I G, Moestue, S A & Itkonen, H M 2020, ' Inhibition of O-GlcNAc transferase activates tumor-suppressor gene expression in tamoxifen-resistant breast cancer cells ', Scientific Reports, vol. 10, no. 1 . https://doi.org/10.1038/s41598-020-74083-z
Scientific Reports
Barkovskaya, A, Seip, K, Prasmickaite, L, Mills, I G, Moestue, S A & Itkonen, H M 2020, ' Inhibition of O-GlcNAc transferase activates tumor-suppressor gene expression in tamoxifen-resistant breast cancer cells ', Scientific Reports, vol. 10, no. 1 . https://doi.org/10.1038/s41598-020-74083-z
In this study, we probed the importance of O-GlcNAc transferase (OGT) activity for the survival of tamoxifen-sensitive (TamS) and tamoxifen-resistant (TamR) breast cancer cells. Tamoxifen is an antagonist of estrogen receptor (ERα), a transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317dcb521aef5b768d4e7116214e272a
http://link.springer.com/article/10.1038/s41598-020-74083-z
http://link.springer.com/article/10.1038/s41598-020-74083-z
Autor:
Nirma Skrbo, Geir-Olav Hjortland, Alexandr Kristian, Ruth Holm, Silje Nord, Lina Prasmickaite, Olav Engebraaten, Gunhild M Mælandsmo, Therese Sørlie, Kristin Andersen
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113278 (2014)
Intratumor heterogeneity caused by genetic, phenotypic or functional differences between cancer cell subpopulations is a considerable clinical challenge. Understanding subpopulation dynamics is therefore central for both optimization of existing ther
Externí odkaz:
https://doaj.org/article/d41254c43b5e469591882c0ff60b9d0e
Autor:
Gunhild Mari Mælandsmo, Solveig Pettersen, Anne Lise Børresen-Dale, Ellen Tenstad, Vessela N. Kristensen, Olav Engebråten, Eivind Valen Egeland, Abhilash D. Pandya, Mads H. Haugen, Shakila Jabeen, Lina Prasmickaite, Silje Nord
Publikováno v:
Molecular Oncology, Vol 12, Iss 9, Pp 1540-1558 (2018)
Molecular Oncology
Molecular Oncology
Source at https://doi.org/10.1002/1878-0261.12319. The tumor microenvironment (TME) may influence both cancer progression and therapeutic response. In breast cancer, particularly in the aggressive triple‐negative/basal‐like subgroup, patient outc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e709bb5efc113a93f3523ae2deb7decb
https://doi.org/10.1002/1878-0261.12319
https://doi.org/10.1002/1878-0261.12319