Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Lin-zhuan Wu"'
Publikováno v:
Cancer Chemotherapy and Pharmacology. 75:773-782
To find novel potential and less toxic benquinone anamycin heat shock protein 90 (Hsp90) inhibitors as anticancer agents, a limited series of 17-substituted or 17,19-disubstituted 17-demethoxygeldanamycin analogs were synthesized and tested for anti-
Autor:
Li-jie, Zuo, Wei, Zhao, Zhi-bo, Jiang, Bing-ya, Jiang, Shu-fen, Li, Hong-yu, Liu, Li-yan, Yu, Bin, Hong, Xin-xin, Hu, Xue-fu, You, Lin-zhuan, Wu
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 51(1)
Chuangxinmycin (CM) from Actinoplanes tsinanensis was an antibiotic discovered by Chinese scientists about 40 years ago. It contains a new heterocyclic system of indole fused with dihydrothiopyran, whose biosynthetic mechanism remains unclear. CM is
Autor:
Lin-Zhuan, Wu, Bin, Hong
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 48(2)
Microbial secondary metabolites are one of the major sources of anti-bacterial, anti-fungal, antitumor, anti-virus and immunosuppressive agents for clinical use. Present challenges in microbial pharmaceutical development are the discovery of novel se