Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Lin-lin Xu"'
Autor:
Shao-Qing Shi, Chen-Chang Cui, Lin-Lin Xu, Jin-Peng Zhang, Wen-Juan Hao, Jianyi Wang, Bo Jiang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Inherently chiral medium-ring derivatives have important applications in many research fields, such as materials science, molecular recognition, and asymmetric catalysis. However, the enantioselective assembly of these molecules, especially
Externí odkaz:
https://doaj.org/article/75bed3d57354470cb2ff745ec21d51bb
Publikováno v:
Green Synthesis and Catalysis, Vol 5, Iss 3, Pp 165-169 (2024)
A palladium/chiral N,N′-disulfonyl bisimidazoline (Bim)-catalyzed asymmetric addition of arylboronic acids to isoquinoline-1,3,4-trione-derived ketimines is reported, leading to the generation of a series of functionalized isoquinoline-1,3(2H,4H)-d
Externí odkaz:
https://doaj.org/article/7cb49de4a0aa4711b157b4bf3bdc722c
Autor:
Chao Chen, Cai-Jin Lin, Yu-Chen Pei, Ding Ma, Li Liao, Si-Yuan Li, Lei Fan, Gen-Hong Di, Song-Yang Wu, Xi-Yu Liu, Yun-Jin Wang, Qi Hong, Guo-Liang Zhang, Lin-Lin Xu, Bei-Bei Li, Wei Huang, Jin-Xiu Shi, Yi-Zhou Jiang, Xin Hu, Zhi-Ming Shao
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-22 (2023)
Abstract Germline-somatic mutation interactions are universal and associated with tumorigenesis, but their role in breast cancer, especially in non-Caucasians, remains poorly characterized. We performed large-scale prospective targeted sequencing of
Externí odkaz:
https://doaj.org/article/e84cc79299584a45a1cc58c8e60cfc41
Autor:
Mohammad H. Mirhakkak, Xiuqiang Chen, Yueqiong Ni, Thorsten Heinekamp, Tongta Sae-Ong, Lin-Lin Xu, Oliver Kurzai, Amelia E. Barber, Axel A. Brakhage, Sebastien Boutin, Sascha Schäuble, Gianni Panagiotou
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Aspergillus fumigatus, an opportunistic human pathogen, frequently infects the lungs of people with cystic fibrosis and is one of the most common causes of infectious-disease death in immunocompromised patients. Here, we construct 252 strain
Externí odkaz:
https://doaj.org/article/e8d5fb99e5474f61bb345e85e225884e
Autor:
Lin-Lin Xu, Di Zhang, Hao-Yi Weng, Li-Zhong Wang, Ruo-Yan Chen, Gang Chen, Su-Fang Shi, Li-Jun Liu, Xu-Hui Zhong, Shen-Da Hong, Li-Xin Duan, Ji-Cheng Lv, Xu-Jie Zhou, Hong Zhang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundImmunoglobulin A nephropathy (IgAN) is one of the leading causes of end-stage kidney disease (ESKD). Many studies have shown the significance of pathological manifestations in predicting the outcome of patients with IgAN, especially T-score
Externí odkaz:
https://doaj.org/article/3ef67e3f2090412ca28d09f174dacb13
Autor:
Lin-Lin Xu, Ting Gan, Yang Li, Pei Chen, Su-Fang Shi, Li-Jun Liu, Ji-Cheng Lv, Hong Zhang, Xu-Jie Zhou
Publikováno v:
Kidney Diseases, Pp 1-1 (2024)
Introduction: IgA nephropathy (IgAN) is a leading cause of end-stage renal disease. The exact pathogenesis of IgAN is not well defined, but some genetic studies have led to a novel discovery that the (immuno)proteasome probably plays an important rol
Externí odkaz:
https://doaj.org/article/62eaa1af4a7a426aa07fd5836c7c139c
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Identification of lysine (symbol Lys or K) succinylation (Ksucc) sites centralizes the basis for disclosing the mechanism and function of lysine succinylation modifications. Traditional experimental methods for Ksucc site ientification are often cost
Externí odkaz:
https://doaj.org/article/e46815808a2d4128b01a7e7042276c6b
Publikováno v:
Guoji Yanke Zazhi, Vol 19, Iss 2, Pp 275-279 (2019)
AIM: To study glucagon-like peptide-1(GLP-1)analogues(liraglutide)in patients with mild to moderate nonproliferative diabetic retinopathy(NPDR)and the clinical efficacy of retinal neuroprotection.METHODS: Sixty patients with type 2 diabetes mellitus
Externí odkaz:
https://doaj.org/article/8e6f051766824933bd7b85aa4e2f413a
Autor:
Hong-Lei Zhang, Hao-Long Dong, Ya-Nan Zhang, Lin-Lin Xu, Cheng-Lin Deng, Xiao-Feng Li, Xiao-Dan Li, Han-Qing Ye, Zhi-Ming Yuan, Cheng-Feng Qin, Bo Zhang
Publikováno v:
Emerging Microbes and Infections, Vol 8, Iss 1, Pp 1574-1583 (2019)
ABSTRACTChikungunya virus (CHIKV), a mosquito-borne alphavirus, has become an important re-emerging pathogen with its rapid spread to many non-endemic areas. The lack of effective vaccines and antiviral agents is largely attributed to the elusive inf
Externí odkaz:
https://doaj.org/article/b2f637c5714143a5856899c95132b6f6
Autor:
Cheng-Lin Deng, Si-Qing Liu, Dong-Gen Zhou, Lin-Lin Xu, Xiao-Dan Li, Pan-Tao Zhang, Peng-Hui Li, Han-Qing Ye, Hong-Ping Wei, Zhi-Ming Yuan, Cheng-Feng Qin, Bo Zhang
Publikováno v:
Viruses, Vol 8, Iss 7, p 181 (2016)
Chikungunya virus (CHIKV), a member of the Alphavirus genus, is an important human emerging/re-emerging pathogen. Currently, there are no effective antiviral drugs or vaccines against CHIKV infection. Herein, we construct an infectious clone of CHIKV
Externí odkaz:
https://doaj.org/article/a6415bc3a2514f44b1aaaa6cd37ab1b4