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Engineered CBEs based on Macaca fascicularis A3A with improved properties for precise genome editing
Autor:
Chun-Yan Ren, Yan-Shan Liu, Yu-Shan He, Lin-Pei Zhang, Jun-Hua Rao, Yijian Rao, Jian-Huan Chen
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113878- (2024)
Summary: Cytidine deaminase defines the properties of cytosine base editors (CBEs) for C-to-T conversion. Replacing the cytidine deaminase rat APOBEC1 (rA1) in CBEs with a human APOBEC3A (hA3A) improves CBE properties. However, the potential CBE appl
Externí odkaz:
https://doaj.org/article/649db4d3376b4527a6c7b19ff185ffe3
