Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Lin-Jiang Tong"'
Autor:
Hong Zhu, Ze-Hong Miao, Min Huang, Jian-Ming Feng, Zhi-Xiang Zhang, Jin-Jian Lu, Yu-Jun Cai, Lin-Jiang Tong, Yu-Fang Xu, Xu-Hong Qian, Jian Ding
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 11, Pp 1226-1234 (2009)
Naphthalimides, particularly amonafide and 2-(2-dimethylamino)-6-thia-2-aza-benzo[def]chrysene-1,3-diones (R16), have been identified to possess anticancer activities and to induce G2-M arrest through inhibiting topoisomerase II accompanied by Chk1 d
Externí odkaz:
https://doaj.org/article/04ca296a405a467da758a9e696d453ac
Autor:
Ze-Hong Miao, Jing-Kang Shen, Jian Ding, Yi Chen, Lin-Jiang Tong, Lan-Ping Ma, Xia-Juan Huan, Jun-Mei Yi, Tao Meng, Ying-Qing Wang, Wei Wang
PDF - 84K, Legends for Supplementary Figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5993ad4e2f9c2bd8ad5bac8c2be322ab
https://doi.org/10.1158/1535-7163.22500784.v1
https://doi.org/10.1158/1535-7163.22500784.v1
Autor:
Ze-Hong Miao, Jing-Kang Shen, Jian Ding, Yi Chen, Lin-Jiang Tong, Lan-Ping Ma, Xia-Juan Huan, Jun-Mei Yi, Tao Meng, Ying-Qing Wang, Wei Wang
PDF - 194K, MT189 causes cellular microtubulin depolymerization in a time-dependent manner and induces reversible M arrest.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4623975ae1c0433583955777920f0d41
https://doi.org/10.1158/1535-7163.22500799
https://doi.org/10.1158/1535-7163.22500799
Autor:
Ze-Hong Miao, Jing-Kang Shen, Jian Ding, Yi Chen, Lin-Jiang Tong, Lan-Ping Ma, Xia-Juan Huan, Jun-Mei Yi, Tao Meng, Ying-Qing Wang, Wei Wang
PDF - 37K, MT189 inhibits the proliferation of HeLa and SMMC-7721 cells in a time- and concentration-dependent manner.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0f8157cd51802001e5c4840fd4b74d
https://doi.org/10.1158/1535-7163.22500796
https://doi.org/10.1158/1535-7163.22500796
Autor:
Ze-Hong Miao, Jing-Kang Shen, Jian Ding, Yi Chen, Lin-Jiang Tong, Lan-Ping Ma, Xia-Juan Huan, Jun-Mei Yi, Tao Meng, Ying-Qing Wang, Wei Wang
Colchicine site–targeted tubulin inhibitors are a promising type of anticancer drugs. MT189 is a new derivative of MT119, a previously reported colchicine site–binding antitubulin agent. In this study, MT189 was demonstrated to retain the propert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46801cd2710063bef7c66d16d65c4bec
https://doi.org/10.1158/1535-7163.c.6536575.v1
https://doi.org/10.1158/1535-7163.c.6536575.v1
Autor:
Ze-Hong Miao, Jing-Kang Shen, Jian Ding, Yi Chen, Lin-Jiang Tong, Lan-Ping Ma, Xia-Juan Huan, Jun-Mei Yi, Tao Meng, Ying-Qing Wang, Wei Wang
PDF - 636K, Whether MT189 induces the colocalization of JNK or p-JNK with α-tubulin was examined by confocal microscopy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29c794a864158c6378f9f1aaca4a9c7e
https://doi.org/10.1158/1535-7163.22500787.v1
https://doi.org/10.1158/1535-7163.22500787.v1
Autor:
Ze-Hong Miao, Jing-Kang Shen, Jian Ding, Yi Chen, Lin-Jiang Tong, Lan-Ping Ma, Xia-Juan Huan, Jun-Mei Yi, Tao Meng, Ying-Qing Wang, Wei Wang
PDF - 18K, The chemical structure of MT189 and its synthesis approach.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05dcdb91fed02d06c9531dcb1bad5520
https://doi.org/10.1158/1535-7163.22500805
https://doi.org/10.1158/1535-7163.22500805
Autor:
Ze-Hong Miao, Jing-Kang Shen, Jian Ding, Yi Chen, Lin-Jiang Tong, Lan-Ping Ma, Xia-Juan Huan, Jun-Mei Yi, Tao Meng, Ying-Qing Wang, Wei Wang
PDF - 21K, MT189 displays an enhanced in vitro proliferation-inhibitory activity when compared with its parental compound MT119.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2690fde3aaf695daa91cbfa8d36aa9e6
https://doi.org/10.1158/1535-7163.22500802.v1
https://doi.org/10.1158/1535-7163.22500802.v1
Autor:
Ze-Hong Miao, Jing-Kang Shen, Jian Ding, Yi Chen, Lin-Jiang Tong, Lan-Ping Ma, Xia-Juan Huan, Jun-Mei Yi, Tao Meng, Ying-Qing Wang, Wei Wang
PDF - 44K, MT189 changes the levels of MCL-1 protein and induces apoptosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7545ebc7cf2daa59703688a9d61f49a1
https://doi.org/10.1158/1535-7163.22500793.v1
https://doi.org/10.1158/1535-7163.22500793.v1
Autor:
Jian Ding, Yanan Wang, Tao Zhang, Yan Li Li, Hua Xie, Yi Su, Ke Ding, Meiyu Geng, Yu Zhe Chen, Yi Chen, Yan Yan Shen, Ying Qiang Liu, Xiaoyun Lu, Lin Jiang Tong, Fang Feng, Yan Li, Qiu Ju Xun
Colony-stimulating factor 1 receptor (CSF1R) plays a critical role in promoting tumor progression in various types of tumors. Here, we identified D2923 as a novel and selective inhibitor of CSF1R and explored its antitumor activity both in vitro and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::255c369df01a31c8f6027aa7b80c929a
https://europepmc.org/articles/PMC6289367/
https://europepmc.org/articles/PMC6289367/