Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions

Autor: Binsheng Gong, Dan Li, Rebecca Kusko, Natalia Novoradovskaya, Yifan Zhang, Shangzi Wang, Carlos Pabón-Peña, Zhihong Zhang, Kevin Lai, Wanshi Cai, Jennifer S. LoCoco, Eric Lader, Todd A. Richmond, Vinay K. Mittal, Liang-Chun Liu, Donald J. Johann, James C. Willey, Pierre R. Bushel, Ying Yu, Chang Xu, Guangchun Chen, Daniel Burgess, Simon Cawley, Kristina Giorda, Nathan Haseley, Fujun Qiu, Katherine Wilkins, Hanane Arib, Claire Attwooll, Kevin Babson, Longlong Bao, Wenjun Bao, Anne Bergstrom Lucas, Hunter Best, Ambica Bhandari, Halil Bisgin, James Blackburn, Thomas M. Blomquist, Lisa Boardman, Blake Burgher, Daniel J. Butler, Chia-Jung Chang, Alka Chaubey, Tao Chen, Marco Chierici, Christopher R. Chin, Devin Close, Jeffrey Conroy, Jessica Cooley Coleman, Daniel J. Craig, Erin Crawford, Angela del Pozo, Ira W. Deveson, Daniel Duncan, Agda Karina Eterovic, Xiaohui Fan, Jonathan Foox, Cesare Furlanello, Abhisek Ghosal, Sean Glenn, Meijian Guan, Christine Haag, Xinyi Hang, Scott Happe, Brittany Hennigan, Jennifer Hipp, Huixiao Hong, Kyle Horvath, Jianhong Hu, Li-Yuan Hung, Mirna Jarosz, Jennifer Kerkhof, Benjamin Kipp, David Philip Kreil, Paweł Łabaj, Pablo Lapunzina, Peng Li, Quan-Zhen Li, Weihua Li, Zhiguang Li, Yu Liang, Shaoqing Liu, Zhichao Liu, Charles Ma, Narasimha Marella, Rubén Martín-Arenas, Dalila B. Megherbi, Qingchang Meng, Piotr A. Mieczkowski, Tom Morrison, Donna Muzny, Baitang Ning, Barbara L. Parsons, Cloud P. Paweletz, Mehdi Pirooznia, Wubin Qu, Amelia Raymond, Paul Rindler, Rebecca Ringler, Bekim Sadikovic, Andreas Scherer, Egbert Schulze, Robert Sebra, Rita Shaknovich, Qiang Shi, Tieliu Shi, Juan Carlos Silla-Castro, Melissa Smith, Mario Solís López, Ping Song, Daniel Stetson, Maya Strahl, Alan Stuart, Julianna Supplee, Philippe Szankasi, Haowen Tan, Lin-ya Tang, Yonghui Tao, Shraddha Thakkar, Danielle Thierry-Mieg, Jean Thierry-Mieg, Venkat J. Thodima, David Thomas, Boris Tichý, Nikola Tom, Elena Vallespin Garcia, Suman Verma, Kimbley Walker, Charles Wang, Junwen Wang, Yexun Wang, Zhining Wen, Valtteri Wirta, Leihong Wu, Chunlin Xiao, Wenzhong Xiao, Shibei Xu, Mary Yang, Jianming Ying, Shun H. Yip, Guangliang Zhang, Sa Zhang, Meiru Zhao, Yuanting Zheng, Xiaoyan Zhou, Christopher E. Mason, Timothy Mercer, Weida Tong, Leming Shi, Wendell Jones, Joshua Xu

Publikováno v: Genome Biology, Vol 22, Iss 1, Pp 1-23 (2021)

Abstract Background Targeted sequencing using oncopanels requires comprehensive assessments of accuracy and detection sensitivity to ensure analytical validity. By employing reference materials characterized by the U.S. Food and Drug Administration-l

Externí odkaz: https://doaj.org/article/c5365bb671514dddbb3d5b324f62ed28

FusionPDB: a unique knowledgebase of human fusion proteins of consistent annotation across genomic/ transcript/ protein/ interaction levels

Autor: Himansu Kumar, Lin-Ya Tang, Chengyuan Yang, Pora Kim

Tumorigenic functions due to the formation of fusion genes were targeted for cancer therapeutics (i.e., kinase inhibitors). However, there are still many fusion proteins awaiting being targeted for therapeutics with multiple different mechanisms. Due

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aff0247f6f9a922305a22135d82379b5
https://doi.org/10.21203/rs.3.rs-2188660/v1

A Study of Five Select Lieder from Hugo Wolf's 'Gedichte von Eduard Mörike'

Autor: Lin Ya Tang, 林雅棠

106
This paper is to explore the poem and music of Hugo Wolf (1860-1903) on “Gedichte von Eduard Mörike”, which is divided into five chapters. The first chapter is an introduction to explain the research motivation, purpose, scope and metho

Externí odkaz: http://ndltd.ncl.edu.tw/handle/as943r

HGG-09. A ROBUST CELL-FREE DNA (CFDNA) ASSAY TO DETECT MUTATIONS IN PLASMA SAMPLES OF PEDIATRIC HIGH GRADE GLIOMA PATIENTS DESPITE GENOMIC DNA (GDNA) CONTAMINATION

Autor: Heather Meador, Wafik Zaky, Najat C. Daw, Lin-ya Tang, Ping Song, Jonathan Gill, Agda Karina Eterovic, Shulin Li, Nader Ezzeddine, Michelle A.T. Hildebrandt, Mohammad M. Mohammad, Soumen Khatua

Publikováno v: Neuro-Oncology. 21:ii88-ii88

Midline K27M gliomas are the most challenging type of gliomas in pediatric patients with very poor outcome (median survival, 9–12 months). Because their anatomic location, brainstem and thalamic gliomas are inoperable and hence no tissue is availab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c193b4852554a463d64b7bd8c0a80446
https://doi.org/10.1093/neuonc/noz036.103

High-Resolution Decay-Pion Spectroscopy of $_\Lambda ^4\text{H}$ Hypernuclei

Autor: Y. Fujii, Amur Margaryan, Lin-Ya Tang, Manami Fujita, L. Correa, U. Müller, Masashi Kaneta, Simon Širca, B. S. Schlimme, C. Sfienti, P. Achenbach, S. Aulenbacher, Sho Nagao, M. Mihovilovic, M. Steinen, W. Kusaka, R. Böhm, Ivica Friščić, F. Schulz, J. Beričič, M. Schoth, Hiroki Kanda, Michaela Thiel, A. Tyukin, Toshiyuki Gogami, Kyo Tsukada, H. Fonvieille, A. Weber, S. N. Nakamura, M. O. Distler, Y. Takahashi, Anselm Esser, Harald Merkel, D. Bosnar, S. Bleser, S. Kegel, J. Pochodzalla, A. Sanchez Lorente, Y. Kohl

Publikováno v: JPS Conf.Proc.
12th International Conference on Hypernuclear and Strange Particle Physics
12th International Conference on Hypernuclear and Strange Particle Physics, Sep 2015, Sendai, Japan. pp.011001, ⟨10.7566/JPSCP.17.011001⟩

International audience; The first observation of \({}_{\Lambda }^{4}\text{H}\) fragments by means of decay-pion spectroscopy with a high resolution magnetic spectrometer was achieved in 2012 at the Mainz Microtron MAMI. The extracted Λ binding energ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb65604657773d03117de423f5f4979e
https://hal.archives-ouvertes.fr/hal-01584623