Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lin Tze Tung"'
Autor:
Yue Liang, HanChen Wang, Noé Seija, Yun Hsiao Lin, Lin Tze Tung, Javier M. Di Noia, David Langlais, Anastasia Nijnik
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionBAP1 is a deubiquitinase (DUB) of the Ubiquitin C-terminal Hydrolase (UCH) family that regulates gene expression and other cellular processes, through its direct catalytic activity on the repressive epigenetic mark histone H2AK119ub, as w
Externí odkaz:
https://doaj.org/article/2d7114a19c9f4754966093185d4ffaf5
Autor:
Yue Liang, Garvit Bhatt, Lin Tze Tung, HanChen Wang, Joo Eun Kim, Marwah Mousa, Viktoria Plackoska, Katalin Illes, Anna A. Georges, Philippe Gros, Linda Henneman, Ivo J. Huijbers, Bhushan Nagar, Anastasia Nijnik
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Myb-like SWIRM and MPN domains 1 (MYSM1) is a chromatin binding protein with deubiquitinase (DUB) catalytic activity. Rare MYSM1 mutations in human patients result in an inherited bone marrow failure syndrome, highlighting the biomedical sig
Externí odkaz:
https://doaj.org/article/937eeed544fb4764a51b1ba8906b06f2
Autor:
Lin Tze Tung, HanChen Wang, Jad I. Belle, Jessica C. Petrov, David Langlais, Anastasia Nijnik
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-13 (2021)
Abstract Stem and progenitor cells are the main mediators of tissue renewal and repair, both under homeostatic conditions and in response to physiological stress and injury. Hematopoietic system is responsible for the regeneration of blood and immune
Externí odkaz:
https://doaj.org/article/9cf402d273f94ed29afc220f1c0d0a67
Autor:
Rayoun Ramendra, Mathieu Mancini, Jose-Mauricio Ayala, Lin Tze Tung, Stephane Isnard, John Lin, Jean-Pierre Routy, Anastasia Nijnik, David Langlais
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
(1→3)-β-D-Glucan (BDG) represents a potent pathogen-associated molecular pattern (PAMP) in triggering the host response to fungal and some bacterial infections. Monocytes play a key role in recognizing BDG and governing the acute host response to
Externí odkaz:
https://doaj.org/article/254699ac6a0b42219bb8f73ee1c5c702
Autor:
Yun Hsiao Lin, Yue Liang, HanChen Wang, Lin Tze Tung, Michael Förster, Poorani Ganesh Subramani, Javier M. Di Noia, Simon Clare, David Langlais, Anastasia Nijnik
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BAP1 is a deubiquitinase (DUB) of the Ubiquitin C-terminal Hydrolase (UCH) family that regulates gene expression and other cellular processes, via deubiquitination of histone H2AK119ub and other substrates. BAP1 is an important tumor suppressor in hu
Externí odkaz:
https://doaj.org/article/4076c37e029f441b87659d41ea81123b
Autor:
Michael Förster, Anastasia Nijnik, HanChen Wang, Jad I. Belle, Amanda Fiore, Yun Hsiao Lin, Jerry Pelletier, David Langlais, Francis Robert, Lin Tze Tung
Publikováno v:
Journal of Cellular and Molecular Medicine
MYSM1 is a chromatin‐binding protein, widely investigated for its functions in haematopoiesis in human and mouse; however, its role in haematologic malignancies remains unexplored. Here, we investigate the cross‐talk between MYSM1 and oncogenic c