Epigenetic Silencing of STAT3-Targeted miR-193a, by Constitutive Activation of JAK/STAT Signaling, Leads to Tumor Progression Through Overexpression of YWHAZ in Gastric Cancer.

Autor: Wei KL; Division of Gastroenterology, Chang Gung Memorial Hospital, Chiayi, Taiwan., Chou JL; Division of Gastroenterology, Chang Gung Memorial Hospital, Chiayi, Taiwan.; Department of Biomedical Sciences, National Chung Cheng University, Chiayi, Taiwan.; Instrument Center, Department of Research and Development, National Defense Medical Center, Taipei, Taiwan., Chen YC; Division of Gastroenterology, Chang Gung Memorial Hospital, Chiayi, Taiwan., Low JT; Division of Gastroenterology, Chang Gung Memorial Hospital, Chiayi, Taiwan.; Department of Biomedical Sciences, National Chung Cheng University, Chiayi, Taiwan., Lin GL; Department of Biomedical Sciences, National Chung Cheng University, Chiayi, Taiwan., Liu JL; Department of Anatomical Pathology, Chang Gung Memorial Hospital, Chiayi, Taiwan., Chang TS; Division of Gastroenterology, Chang Gung Memorial Hospital, Chiayi, Taiwan., Chen WM; Division of Gastroenterology, Chang Gung Memorial Hospital, Chiayi, Taiwan., Hsieh YY; Division of Gastroenterology, Chang Gung Memorial Hospital, Chiayi, Taiwan., Yan PS; Division of Hematology, Department of Internal Medicine, Comprehensive Cancer Center, The Ohio State University, Columbus, OH, United States., Chuang YM; Department of Biomedical Sciences, National Chung Cheng University, Chiayi, Taiwan., Lin JMJ; Department of Biomedical Sciences, National Chung Cheng University, Chiayi, Taiwan., Wu SF; Department of Biomedical Sciences, National Chung Cheng University, Chiayi, Taiwan.; Epigenomics and Human Disease Research Center, National Chung Cheng University, Chiayi, Taiwan., Chiang MK; Department of Biomedical Sciences, National Chung Cheng University, Chiayi, Taiwan., Li C; Department of Biomedical Sciences, National Chung Cheng University, Chiayi, Taiwan.; Epigenomics and Human Disease Research Center, National Chung Cheng University, Chiayi, Taiwan., Wu CS; Division of Gastroenterology, Chang Gung Memorial Hospital, Chiayi, Taiwan., Chan MWY; Department of Biomedical Sciences, National Chung Cheng University, Chiayi, Taiwan.; Epigenomics and Human Disease Research Center, National Chung Cheng University, Chiayi, Taiwan.; Center for Innovative Research on Aging Society (CIRAS), National Chung Cheng University, Chiayi, Taiwan.

Publikováno v: Frontiers in oncology [Front Oncol] 2021 Feb 25; Vol. 11, pp. 575667. Date of Electronic Publication: 2021 Feb 25 (Print Publication: 2021).

E2F6 functions as a competing endogenous RNA, and transcriptional repressor, to promote ovarian cancer stemness.

Autor: Cheng FHC; Department of Biomedical Sciences, National Chung Cheng University, Chia-Yi, Taiwan.; Epigenomics and Human Disease Research Center, National Chung Cheng University, Chia-Yi, Taiwan., Lin HY; Department of Radiation Oncology, Buddhist Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chia-Yi, Taiwan.; School of Medicine, Tzu Chi University, Hualien, Taiwan., Hwang TW; Department of Mathematics, National Chung Cheng University, Chia-Yi, Taiwan., Chen YC; Department of Biomedical Sciences, National Chung Cheng University, Chia-Yi, Taiwan.; Epigenomics and Human Disease Research Center, National Chung Cheng University, Chia-Yi, Taiwan., Huang RL; Department of Obstetrics and Gynecology, School of Medicine, College of Medicine and Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan., Chang CB; Department of Biomedical Sciences, National Chung Cheng University, Chia-Yi, Taiwan.; Epigenomics and Human Disease Research Center, National Chung Cheng University, Chia-Yi, Taiwan., Yang W; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China., Lin RI; Department of Radiation Oncology, Buddhist Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chia-Yi, Taiwan., Lin CW; Department of Biomedical Sciences, National Chung Cheng University, Chia-Yi, Taiwan.; Epigenomics and Human Disease Research Center, National Chung Cheng University, Chia-Yi, Taiwan., Chen GCW; Department of Biomedical Sciences, National Chung Cheng University, Chia-Yi, Taiwan.; Epigenomics and Human Disease Research Center, National Chung Cheng University, Chia-Yi, Taiwan., Mai SY; Department of Biomedical Sciences, National Chung Cheng University, Chia-Yi, Taiwan., Lin JMJ; Department of Biomedical Sciences, National Chung Cheng University, Chia-Yi, Taiwan.; Epigenomics and Human Disease Research Center, National Chung Cheng University, Chia-Yi, Taiwan., Chuang YM; Department of Biomedical Sciences, National Chung Cheng University, Chia-Yi, Taiwan.; Epigenomics and Human Disease Research Center, National Chung Cheng University, Chia-Yi, Taiwan., Chou JL; Department of Biomedical Sciences, National Chung Cheng University, Chia-Yi, Taiwan.; Epigenomics and Human Disease Research Center, National Chung Cheng University, Chia-Yi, Taiwan., Kuo LW; Department of Biomedical Sciences, National Chung Cheng University, Chia-Yi, Taiwan.; Epigenomics and Human Disease Research Center, National Chung Cheng University, Chia-Yi, Taiwan., Li C; Department of Biomedical Sciences, National Chung Cheng University, Chia-Yi, Taiwan., Cheng ASL; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China., Lai HC; Department of Obstetrics and Gynecology, School of Medicine, College of Medicine and Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan., Wu SF; Department of Biomedical Sciences, National Chung Cheng University, Chia-Yi, Taiwan.; Epigenomics and Human Disease Research Center, National Chung Cheng University, Chia-Yi, Taiwan., Tsai JC; Department of Mathematics, National Tsing Hua University, Hsin-Chu, Taiwan., Chan MWY; Department of Biomedical Sciences, National Chung Cheng University, Chia-Yi, Taiwan.; Epigenomics and Human Disease Research Center, National Chung Cheng University, Chia-Yi, Taiwan.; Center for Innovative Research on Aging Society (CIRAS), National Chung Cheng University, Chia-Yi, Taiwan.; Research Center for Environmental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.

Publikováno v: Cancer science [Cancer Sci] 2019 Mar; Vol. 110 (3), pp. 1085-1095. Date of Electronic Publication: 2019 Jan 25.