Zobrazeno 1 - 10
of 1 315
pro vyhledávání: '"Limulus amebocyte lysate"'
Autor:
Gabriela Solano, Stuart Ainsworth, Adriana Sánchez, Mauren Villalta, Paola Sánchez, Gina Durán, José María Gutiérrez, Guillermo León
Publikováno v:
Toxicon: X, Vol 21, Iss , Pp 100187- (2024)
As injectable therapeutics, snake antivenoms must meet specifications for endotoxin content. The Limulus amebocyte lysate (LAL) test was used to evaluate the endotoxin content in several commercially available antivenoms released for clinical use. It
Externí odkaz:
https://doaj.org/article/cce0b6f96a6b4a528fa208ecb94d3780
Autor:
Da Hee Kang, Song Yeol Yun, SoYoung Eum, Kyung Eun Yoon, Seung-Rel Ryu, Chulhyun Lee, Hye-Ryeon Heo, Kwang Moon Lee
Publikováno v:
Microorganisms, Vol 12, Iss 3, p 516 (2024)
Gram-negative bacterial endotoxins can cause pathophysiological effects such as high fever when introduced into the bloodstream. Therefore, endotoxin testing is necessary when producing injectable pharmaceuticals. The pharmaceutical industry has wide
Externí odkaz:
https://doaj.org/article/a590a43288024732938f83170247b1b8
Akademický článek
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Publikováno v:
Asia Oceania Journal of Nuclear Medicine and Biology, Vol 10, Iss 2, Pp 109-116 (2022)
Objective(s): Bacterial endotoxin test (BET) for detection and quantification of endotoxin in radiopharmaceuticals (RPs), used for therapy or diagnosis, is prerequisite to administration in patients. Out of the two established methods used for this p
Externí odkaz:
https://doaj.org/article/ab270ba6aaf542b892c6218a4a77cdd8
Autor:
Salvatore Pasqua, Maria Concetta Niotta, Giuseppina Di Martino, Davide Sottile, Bruno Douradinha, Monica Miele, Francesca Timoneri, Mariangela Di Bella, Nicola Cuscino, Chiara Di Bartolo, Pier Giulio Conaldi, Danilo D’Apolito
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss , Pp 320-329 (2021)
Endotoxin content is a critical factor that affects the safety of biological pharmaceutical products. International pharmacopoeias describe several reference methods to determine endotoxin levels in advanced therapy medicinal product (ATMP) preparati
Externí odkaz:
https://doaj.org/article/003d1bb7774b440285018e95821eda62
Akademický článek
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Publikováno v:
BioTechniques, Vol 68, Iss 6, Pp 300-304 (2020)
We devised a method using dextran for obtaining leukocyte-rich plasma (LRP) to measure endotoxin in blood. In order to find the optimal temperature for obtaining LRP, the measurement results were examined using samples prepared at 37 and 0°C. Sample
Externí odkaz:
https://doaj.org/article/5b257417e67a403287197e5160d48937
Autor:
Kentaro Ito, Kumi Y. Inoue, Takahiro Ito-Sasaki, Miho Ikegawa, Shinichiro Takano, Kosuke Ino, Hitoshi Shiku
Publikováno v:
Micromachines, Vol 14, Iss 2, p 327 (2023)
The Limulus amebocyte lysate (LAL) reaction-based assay, the most commonly used endotoxin detection method, requires a skilled technician. In this study, to develop an easy-to-use and highly sensitive endotoxin sensor, we created an electrochemical e
Externí odkaz:
https://doaj.org/article/9a8074a3276d4ee398d80ca338deafb2
Publikováno v:
Animals, Vol 13, Iss 3, p 427 (2023)
Mastitis, one of the most common diseases in dairy cattle, causes severe losses in the dairy sector worldwide and affects animal welfare. The disease is characterized by an inflammatory reaction of the mammary gland and is mainly caused by bacterial
Externí odkaz:
https://doaj.org/article/847f416d5631446a9130012e08a622e2
Akademický článek
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