Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Limei, Ju"'
Publikováno v:
PLoS Biology, Vol 15, Iss 5, p e2001264 (2017)
Stem and differentiated cells frequently differ in their response to DNA damage, which can determine tissue sensitivity. By exploiting insight into the spatial arrangement of subdomains within the adult neural subventricular zone (SVZ) in vivo, we sh
Externí odkaz:
https://doaj.org/article/18fa567837bc40598ba937c6bdaee98e
Autor:
Fernando Gómez-Herreros, Rocío Romero-Granados, Zhihong Zeng, Alejandro Alvarez-Quilón, Cristina Quintero, Limei Ju, Lieve Umans, Liesbeth Vermeire, Danny Huylebroeck, Keith W Caldecott, Felipe Cortés-Ledesma
Publikováno v:
PLoS Genetics, Vol 9, Iss 3, p e1003226 (2013)
Anticancer topoisomerase "poisons" exploit the break-and-rejoining mechanism of topoisomerase II (TOP2) to generate TOP2-linked DNA double-strand breaks (DSBs). This characteristic underlies the clinical efficacy of TOP2 poisons, but is also implicat
Externí odkaz:
https://doaj.org/article/b6ee006f88034a179df6e3efdebf08fa
Publikováno v:
IOP Conference Series: Materials Science and Engineering. 772:012097
The finite element analysis of a cantilever steel frame structure of the bottom platform in civil engineering is carried out. Based on ANSYS and the basic characteristics of steel frame structure, parametric modelling is carried out, and the stress a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7933cc15948f2f6545cd08ece82b10cb
https://doi.org/10.1088/1757-899x/772/1/012097
https://doi.org/10.1088/1757-899x/772/1/012097
Publikováno v:
Dna repair, 76, 70-75. ELSEVIER SCIENCE BV
Radiosusceptibility is the sensitivity of a biological organism to ionising radiation (IR)-induced carcinogenesis, an outcome of IR exposure relevant following low doses. The tissue response is strongly influenced by the DNA damage response (DDR) act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c196c8139177b1c6e6b6e961b1217916
https://pubmed.ncbi.nlm.nih.gov/30822688
https://pubmed.ncbi.nlm.nih.gov/30822688
Autor:
Emilia Komulainen, Jack Badman, Stephanie Rey, Stuart Rulten, Limei Ju, Kate Fennell, Peter J. McKinnon, Kevin Staras, Keith W Caldecott
Defects in DNA single-strand break repair result in cerebellar ataxia which inXrcc1Nes-Cremice is promoted by hyperactivity of the DNA strand break sensor protein, Parp1. Here, we show that Parp1 hyperactivity extends beyond the cerebellum in Xrcc1-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acc2b27f1cbfa5a75231a67f36d58b0e
https://doi.org/10.1101/431916
https://doi.org/10.1101/431916
Publikováno v:
PLoS Biology, Vol 15, Iss 5, p e2001264 (2017)
PLoS Biology
PLOS BIOLOGY, 15(5):e2001264. PUBLIC LIBRARY SCIENCE
PLoS Biology
PLOS BIOLOGY, 15(5):e2001264. PUBLIC LIBRARY SCIENCE
Stem and differentiated cells frequently differ in their response to DNA damage, which can determine tissue sensitivity. By exploiting insight into the spatial arrangement of subdomains within the adult neural subventricular zone (SVZ) in vivo, we sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb48dfd4836e99672a52e8c2b0e63a0a
http://europepmc.org/articles/PMC5424956?pdf=render
http://europepmc.org/articles/PMC5424956?pdf=render
Autor:
Elaine M. Taylor, Alan R. Lehmann, Birgit Rathkolb, Limei Ju, Jan Rozman, Johannes Beckers, Martin Hrabě de Angelis, Marion Horsch, Valerie Gailus-Durner, Martin Klingenspor, Thure Adler, Jonathan F. Wing, Predrag Slijepcevic, Andreas Zimmer, Helmut Fuchs, Wolfgang Hans, Lore Becker, Renata M. C. Brandt, Thomas Klopstock, Eckhard Wolf, Gilbertus van der Horst, Ildiko Racz, Dirk H. Busch
Publikováno v:
DNA Repair, 12(5), 356-366. Elsevier
Smc5-6 is a highly conserved protein complex related to cohesin and condensin involved in the structural maintenance of chromosomes. In yeasts the Smc5-6 complex is essential for proliferation and is involved in DNA repair and homologous recombinatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f768af24091a1d9121ea3bfbd0c6074a
https://doi.org/10.1016/j.dnarep.2013.02.006
https://doi.org/10.1016/j.dnarep.2013.02.006
Autor:
Alexander, Kukalev, Yiu-Ming, Ng, Limei, Ju, Amal, Saidi, Sophie, Lane, Angeles, Mondragon, Dirk, Dormann, Sophie E, Walker, William, Grey, Philip Wing-Lok, Ho, David N, Stephens, Antony M, Carr, Karri, Lamsa, Eric, Tse, Veronica P C C, Yu
Publikováno v:
Cerebral Cortex (New York, NY)
In mitotic cells, the cyclin-dependent kinase (CDK) subunit protein CKS1 regulates S phase entry by mediating degradation of the CDK inhibitor p27. Although mature neurons lack mitotic CDKs, we found that CKS1 was actively expressed in post-mitotic n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f8b1340dc8201504f8395829f1124fa
https://pubmed.ncbi.nlm.nih.gov/28365778
https://pubmed.ncbi.nlm.nih.gov/28365778
Autor:
Antony M. Carr, Cong Liu, Eva Hoffmann, Zhao-Qi Wang, Ralph Gruber, Penny A. Jeggo, Limei Ju, Susanne A. Gatz
Publikováno v:
Journal of Neuroscience
The embryonic ventricular and subventricular zones (VZ/SVZ) contain the neuronal stem and progenitor cells and undergo rapid proliferation. The intermediate zone (IZ) contains nonreplicating, differentiated cells. The VZ/SVZ is hypersensitive to radi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3847081edbfc28a2a2732d2d077a1e8d
https://doi.org/10.1523/jneurosci.1324-11.2011
https://doi.org/10.1523/jneurosci.1324-11.2011
Autor:
Keith W. Caldecott, Michèle Rouleau, Isabelle Robert, Stuart L. Rulten, Guy G. Poirier, Maria C. Zuma, Bernardo Reina-San-Martin, Limei Ju, Anna E. O. Fisher
Publikováno v:
Molecular Cell. 41:33-45
PARP-3 is a member of the ADP-ribosyl transferase superfamily of unknown function. We show that PARP-3 is stimulated by DNA double-strand breaks (DSBs) in vitro and functions in the same pathway as the poly (ADP-ribose)-binding protein APLF to accele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4673a20f2f793dc32853ad7914bd8278
https://doi.org/10.1016/j.molcel.2010.12.006
https://doi.org/10.1016/j.molcel.2010.12.006