Activation, apoptosis, and clearance of neutrophils in Wegener's granulomatosis

Autor: van Rossum, A.P., Limburg, Piet, Kallenberg, Cees, Shoenfeld, Y., Gershwin, M.E., Shoenfeld, Y, Gershwin, ME

Publikováno v: Autoimmune diseases and treatment : organ-specific and systemic disorders, 1-11
STARTPAGE=1;ENDPAGE=11;TITLE=Autoimmune diseases and treatment : organ-specific and systemic disorders

Wegener's granulomatosis (WG) is strongly associated with the presence of antineutrophil cytoplasmic autoantibodies (ANCAs). Within WG these ANCAs are usually (80-90%) directed against the azurophilic enzyme proteinase 3, the so called PR3-ANCA. A pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::557eb68340b19f5ccc7c5b8cbc38a4b7
https://hdl.handle.net/11370/67cd9e57-2578-4df9-9d0c-31979224ba98

LRegulation of cytokine-induced HW-1 alpha expression in rheumatoid synovial fibroblasts

Autor: BROUWER, E., Bos, R, Posthumus, M.D., Meer, B.D.V.D., Kallenberg, Cees, Limburg, Piet, Westra, H

Publikováno v: Annals of the New York Academy of Sciences, 340-348. Blackwell Publishing Ltd
ISSUE=1108;STARTPAGE=340;ENDPAGE=348;ISSN=0077-8923;TITLE=Annals of the New York Academy of Sciences

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::835fd7cc7679ef6539f0fdedceda1ed8
https://research.rug.nl/en/publications/88e39f6e-4cb0-47df-8fa3-8e6f75a18893

Apoptosis in human skin - Role in pathogenesis of various diseases and relevance for therapy

Autor: Reefman, Esther, Limburg, Piet, Kallenberg, Cees, Bijl, Marc, Shoenfeld, Y., Gershwin, M.E., Shoenfeld, Y, Gershwin, ME

Publikováno v: Autoimmune diseases and treatment : organ-specific and systemic disorders, 52-63
STARTPAGE=52;ENDPAGE=63;TITLE=Autoimmune diseases and treatment : organ-specific and systemic disorders

Cell death by apoptosis is a physiological process that enables the elimination of cells without causing an inflammatory response. In self-renewing tissue like the epidermal layers of the skin, cell numbers are tightly regulated by a delicate balance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a9ed68501059879870657d1193ea03
https://research.rug.nl/en/publications/26e74b17-bfd7-44c4-9c24-c13aa3c28529

Catalase and alpha-enolase: two novel granulocyte autoantigens in inflammatory bowel disease (IBD)

Autor: Roozendaal, C., Zhao, M.H., Lockwood, C.M., Kleibeuker, Jan, Limburg, Piet, Nelis, G.F., Kallenberg, Cees, Horst, G.

Publikováno v: Gastroenterology, 114(4), A1071-A1071. W B SAUNDERS CO-ELSEVIER INC
Clinical and Experimental Immunology, 112(1), 10-16. Wiley

In IBD, the target antigens of anti-neutrophil cytoplasmic autoantibodies (ANCA) have not been fully identified, which limits the analysis of the diagnostic significance as well as of the possible pathophysiological role of these antibodies. In this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::adb631d9b7796b6f0f3640115b1acf78
https://research.rug.nl/en/publications/d50564a9-76a3-4983-91d8-6a4adfb4d793

Antineutrophil cytoplasmic antibodies in juvenile chronic arthritis

Autor: Mulder, Leontine, Van Rossum, Marion, Horst, Gerda, Limburg, Piet, De Graeff-Meeder, Elisabeth R., Kuis, Wietze, Kallenberg, Cees

Publikováno v: Journal of rheumatology, 24(3), 568-575. Journal of Rheumatology

Objective. To evaluate the diagnostic significance of antineutrophil cytoplasmic antibodies (ANCA) by assessing the prevalence of ANCA in juvenile chronic arthritis (JCA) (n = 93) of either oligoarticular, polyarticular, or systemic onset. To investi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::c80e038b5c39c448f3ddd7c7325b5cf9
https://pure.amc.nl/en/publications/antineutrophil-cytoplasmic-antibodies-in-juvenile-chronic-arthritis(78ceb025-af58-4b75-be86-544ce15a3bb5).html