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PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy.

Autor: Wang L; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Cho YL; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Tang Y; School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China., Wang J; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Park JE; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore., Wu Y; Department of Anatomy, National University of Singapore, Singapore, Singapore., Wang C; Biochemistry Section, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, 20892, USA., Tong Y; Department of Biological Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore., Chawla R; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Zhang J; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Department of Oncology, Clinical Research Institute, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, Zhejiang, China., Shi Y; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Deng S; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lu G; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Wu Y; Department of Toxicology, Zhejiang University School of Public Health, Hangzhou, Zhejiang, China., Tan HW; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore., Pawijit P; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lim GG; National Neuroscience Institute, Singapore, Singapore., Chan HY; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore., Zhang J; Jiangsu Key Laboratory of Molecular Medicine, Model Animal Research Center, Medical School of Nanjing University, Nanjing, Jiangsu, China., Fang L; Jiangsu Key Laboratory of Molecular Medicine, Model Animal Research Center, Medical School of Nanjing University, Nanjing, Jiangsu, China., Yu H; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Mechanobiology Institute, National University of Singapore, Singapore, Singapore.; Institute of Bioengineering and Nanotechnology, A*STAR, Singapore, Singapore., Liou YC; Department of Biological Sciences, Faculty of Science, National University of Singapore, Singapore, Singapore., Karthik M; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Bay BH; Department of Anatomy, National University of Singapore, Singapore, Singapore., Lim KL; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; National Neuroscience Institute, Singapore, Singapore., Sze SK; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore., Yap CT; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Shen HM; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. phsshm@nus.edu.sg.; Graduate School for Integrative Sciences and Engineering, National University of Singapore, Singapore, Singapore. phsshm@nus.edu.sg.

Publikováno v: Cell research [Cell Res] 2018 Aug; Vol. 28 (8), pp. 787-802. Date of Electronic Publication: 2018 Jun 22.

Correction: Superoxide drives progression of Parkin/PINK1-dependent mitophagy following translocation of Parkin to mitochondria.

Autor: Xiao B; Department of Neurology, National Neuroscience Institute, Singapore, Singapore., Deng X; Department of Neurology, National Neuroscience Institute, Singapore, Singapore., Lim GG; Neurodegeneration Research Laboratory, National Neuroscience Institute, Singapore, Singapore., Xie S; Department of Research, National Neuroscience Institute, Singapore, Singapore., Zhou ZD; Department of Research, National Neuroscience Institute, Singapore, Singapore., Lim KL; Neurodegeneration Research Laboratory, National Neuroscience Institute, Singapore, Singapore.; Department of Physiology, National University of Singapore, Singapore, Singapore.; Duke-NUS Medical School, National University of Singapore, Singapore, Singapore., Tan EK; Department of Neurology, National Neuroscience Institute, Singapore, Singapore. tan.eng.king@sgh.com.sg.; Department of Neurology, Singapore General Hospital, Singapore, Singapore. tan.eng.king@sgh.com.sg.; Duke-NUS Medical School, National University of Singapore, Singapore, Singapore. tan.eng.king@sgh.com.sg.

Publikováno v: Cell death & disease [Cell Death Dis] 2018 Jul 19; Vol. 9 (8), pp. 794. Date of Electronic Publication: 2018 Jul 19.