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Autor:
Premkumar Jayaraman, Meena Kishore Sakharkar, Kishore R. Sakharkar, Mohammad Imran Siddiqi, Lim Chu Siang Daniel, Sarinder Kaur Dhillon
Publikováno v:
Frontiers in Bioscience. :864-882
In this study, we successfully present the dual-target design hypothesis to inhibit both dihydropteroate synthase (DHPS) and dihydrofolate reductase (DHFR) enzymes using a novel scheme that integrates our previous antibiotic-phytochemical interaction