Dendritic cell-targeted delivery of antigens using extracellular vesicles for anti-cancer immunotherapy.

Autor: Dang XTT; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Phung CD; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lim CMH; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Jayasinghe MK; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Ang J; School of Applied Science, Republic Polytechnic, Woodlands, Singapore., Tran T; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Infectious Disease Translational Research Program, National University of Singapore, Singapore, Singapore.; Immunology Programme, National University of Singapore, Singapore, Singapore., Schwarz H; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Immunology Programme, National University of Singapore, Singapore, Singapore., Le MTN; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Immunology Programme, National University of Singapore, Singapore, Singapore.; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Institute of Molecular and Cell Biology, Agency for Science, Technology, Technology and Research, Singapore, Singapore.

Publikováno v: Cell proliferation [Cell Prolif] 2024 Jul; Vol. 57 (7), pp. e13622. Date of Electronic Publication: 2024 Mar 20.

αvβ1 integrin is enriched in extracellular vesicles of metastatic breast cancer cells: A mechanism mediated by galectin-3.

Autor: Zhang DX; Department of Pharmacology and Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Queenstown, Singapore.; Department of Surgery, Cancer Program, Immunology Program, and Nanomedicine Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Queenstown, Singapore.; Department of Biomedical Sciences, Jocky Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Kowloon, Hong Kong SAR.; Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, USA., Dang XTT; Department of Pharmacology and Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Queenstown, Singapore.; Department of Surgery, Cancer Program, Immunology Program, and Nanomedicine Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Queenstown, Singapore., Vu LT; Department of Pharmacology and Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Queenstown, Singapore.; Department of Surgery, Cancer Program, Immunology Program, and Nanomedicine Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Queenstown, Singapore.; Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, USA., Lim CMH; Department of Pharmacology and Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Queenstown, Singapore.; Department of Surgery, Cancer Program, Immunology Program, and Nanomedicine Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Queenstown, Singapore., Yeo EYM; Department of Pharmacology and Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Queenstown, Singapore.; Department of Surgery, Cancer Program, Immunology Program, and Nanomedicine Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Queenstown, Singapore.; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Queenstown, Singapore., Lam BWS; Department of Pharmacology and Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Queenstown, Singapore.; Department of Surgery, Cancer Program, Immunology Program, and Nanomedicine Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Queenstown, Singapore., Leong SM; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Queenstown, Singapore., Omar N; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Queenstown, Singapore., Putti TC; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Queenstown, Singapore., Yeh YC; Department of Biomedical Sciences, Jocky Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Kowloon, Hong Kong SAR., Ma V; Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong SAR., Luo JY; Department of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China., Cho WC; Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong SAR., Chen G; Department of Pathology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China., Lee VKM; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Queenstown, Singapore., Grimson A; Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York, USA., Le MTN; Department of Pharmacology and Institute for Digital Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Queenstown, Singapore.; Department of Surgery, Cancer Program, Immunology Program, and Nanomedicine Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Queenstown, Singapore.

Publikováno v: Journal of extracellular vesicles [J Extracell Vesicles] 2022 Aug; Vol. 11 (8), pp. e12234.