Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological site

Autor: Matthew, Susan, Chen, Qi-Yin, Ratnayake, Ranjala, Fermaintt, Charles S., Lucena-Agell, Daniel, Bonato, Francesca, Prota, Andrea E., Lim, Seok Ting, Wang, Xiaomeng, Díaz, J. Fernando, Risinger, April L., Paul, Valerie J., Oliva, Maria Ángela, Luesch, Hendrik

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 2021 Mar 01. 118(9), 1-11.

Externí odkaz: https://www.jstor.org/stable/27027426

Islet macrophages are associated with islet vascular remodeling and compensatory hyperinsulinemia during diabetes

Autor: Chittezhath, Manesh, Gunaseelan, Divya, Zheng, Xiaofeng, Hasan, Riasat, Tay, Vanessa S Y, Lim, Seok Ting, Wang, Xiaomeng, Berggren, Per-Olof, Bornstein, Stefan, Boehm, Bernhard, Ruedl, Christiane, Ali, Yusuf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______885::106df9b8649a55ad80f761e5e973facb
https://www.zora.uzh.ch/id/eprint/208292/

Collaborative Regulation of LRG1 by TGF-β1 and PPAR-β/δ Modulates Chronic Pressure Overload–Induced Cardiac Fibrosis.

Autor: Liu, Chenghao, Lim, Seok Ting, Teo, Melissa Hui Yen, Tan, Michelle Si Ying, Kulkarni, Madhura Dattatraya, Qiu, Beiying, Li, Amy, Lal, Sean, dos Remedios, Cristobal G., Tan, Nguan Soon, Wahli, Walter, Ferenczi, Michael Alan, Song, Weihua, Hong, Wanjin, Wang, Xiaomeng

Publikováno v: Circulation: Heart Failure; Dec2019, Vol. 12 Issue 12, pe005962-e005962, 1p

Hypoxia deactivates epigenetic feedbacks via enzyme-derived clicking proteolysis-targeting chimeras.

Autor: Do TC; Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore., Lau JW; Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.; Department of Chemistry, National University of Singapore, Singapore 117543, Singapore., Sun C; Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore., Liu S; Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore., Kha KT; Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore., Lim ST; Duke-NUS Medical School, Singapore 169857, Singapore.; Singapore Eye Research Institute, Singapore 169856, Singapore., Oon YY; School of Biological Sciences, Nanyang Technological University, Singapore 637551, Singapore., Kwan YP; Duke-NUS Medical School, Singapore 169857, Singapore.; Singapore Eye Research Institute, Singapore 169856, Singapore., Ma JJ; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore., Mu Y; School of Biological Sciences, Nanyang Technological University, Singapore 637551, Singapore., Liu X; Department of Chemistry, National University of Singapore, Singapore 117543, Singapore., Carney TJ; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore., Wang X; Duke-NUS Medical School, Singapore 169857, Singapore.; Singapore Eye Research Institute, Singapore 169856, Singapore.; Institute of Molecular and Cell Biology, A*STAR, Singapore 138673, Singapore., Xing B; Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore.; School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, Singapore 637371, Singapore.

Publikováno v: Science advances [Sci Adv] 2022 Dec 14; Vol. 8 (50), pp. eabq2216. Date of Electronic Publication: 2022 Dec 14.