Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

Autor: Couch, Fergus J., Kuchenbaecker, Karoline B., Michailidou, Kyriaki, Mendoza-Fandino, Gustavo A., Nord, Silje, Lilyquist, Janna, Olswold, Curtis, Hallberg, Emily, Agata, Simona, Ahsan, Habibul, Aittomäki, Kristiina, Ambrosone, Christine, Andrulis, Irene L., Anton-Culver, Hoda, Arndt, Volker, Arun, Banu K., Arver, Brita, Barile, Monica, Barkardottir, Rosa, Barrowdale, Daniel, Beckmann, Lars, Beckmann, Matthias W., Benitez, Javier, Blank, Stephanie V., Blomqvist, Carl, Bogdanova, Natalia V., Bojesen, Stig E., Bolla, Manjeet K., Bonanni, Bernardo, Brauch, Hiltrud, Brenner, Hermann, Burwinkel, Barbara, Buys, Saundra S., Caldes, Trinidad, Caligo, Maria A., Canzian, Federico, Carpenter, Jane, Chang-Claude, Jenny, Chanock, Stephen J., Chung, Wendy K., Claes, Kathleen B.M., Cox, Angela, Cross, Simon S., Cunningham, Julie M., Czene, Kamila, Daly, Mary B., Damiola, Francesca, Darabi, Hatef, De La Hoya, Miguel, Devilee, Peter, Diez, Orland, Ding, Yuan C., Dolcetti, Riccardo, Domchek, Susan M., Dorfling, Cecilia M., Dos-Santos-Silva, Isabel, Dumont, Martine, Dunning, Alison M, Eccles, Diana M, Ehrencrona, Hans, Ekici, Arif B, Eliassen, Heather, Ellis, Steve, Fasching, Peter A, Figueroa, Jonine, Flesch-Janys, Dieter, Försti, Asta, Fostira, Florentia, Foulkes, William D, Friebel, Tara, Friedman, Eitan, Frost, Debra, Gabrielson, Marike, Gammon, Marilie D, Ganz, Patricia A, Gapstur, Susan M, Garber, Judy, Gaudet, Mia M, Gayther, Simon A, Gerdes, Anne-Marie, Ghoussaini, Maya, Giles, Graham G, Glendon, Gord, Godwin, Andrew K, Goldberg, Mark S, Goldgar, David E, Gonzalez-Neira, Anna, Greene, Mark H, Gronwald, Jacek, Guenel, Pascal, Gunter, Marc, Haeberle, Lothar, Haiman, Christopher A, Hamann, Ute, Hansen, Thomas V O, Hart, Steven, Healey, Sue, Heikkinen, Tuomas, Henderson, Brian E, Herzog, Josef, Hogervorst, Frans B L, Hollestelle, Antoinette, Hooning, Maartje J, Hoover, Robert N, Hopper, John L, Humphreys, Keith, Hunter, David J, Huzarski, Tomasz, Imyanitov, Evgeny N, Isaacs, Claudine, Jakubowska, Anna, James, Paul, Janavicius, Ramunas, Jensen, Uffe Birk, John, Esther M, Jones, Michael, Kabisch, Maria, Kar, Siddhartha, Karlan, Beth Y, Khan, Sofia, Khaw, Kay-Tee, Kibriya, Muhammad G, Knight, Julia A, Ko, Yon-Dschun, Konstantopoulou, Irene, Kosma, Veli-Matti, Kristensen, Vessela N., Kwong, Ava, Laitman, Yael, Lambrechts, Diether, Lazaro, Conxi, Lee, Eunjung, Le Marchand, Loic, Lester, Jenny, Lindblom, Annika, Lindor, Noralane, Lindstrom, Sara, Liu, Jianjun, Long, Jirong, Lubinski, Jan, Mai, Phuong L, Makalic, Enes, Malone, Kathleen E, Mannermaa, Arto, Manoukian, Siranoush, Margolin, Sara, Marme, Frederik, Martens, John W M, Mcguffog, Lesley, Meindl, Alfons, Miller, Austin, Milne, Roger L, Miron, Penelope, Montagna, Marco, Mazoyer, Sylvie, Mulligan, Anna M, Muranen, Taru A, Nathanson, Katherine L, Neuhausen, Susan L, Nevanlinna, Heli, Nordestgaard, Børge G, Nussbaum, Robert L, Offit, Kenneth, Olah, Edith, Olopade, Olufunmilayo I, Olson, Janet E, Osorio, Ana, Park, Sue K, Peeters, Petra H, Peissel, Bernard, Peterlongo, Paolo, Peto, Julian, Phelan, Catherine M, Pilarski, Robert, Poppe, Bruce, Pylkäs, Katri, Radice, Paolo, Rahman, Nazneen, Rantala, Johanna, Rappaport, Christine, Rennert, Gad, Richardson, Andrea, Robson, Mark, Romieu, Isabelle, Rudolph, Anja, Rutgers, Emiel J, Sanchez, Maria-Jose, Santella, Regina M, Sawyer, Elinor J, Schmidt, Daniel F, Schmidt, Marjanka K, Schmutzler, Rita K, Schumacher, Fredrick, Scott, Rodney, Senter, Leigha, Sharma, Priyanka, Simard, Jacques, Singer, Christian F, Sinilnikova, Olga M, Soucy, Penny, Southey, Melissa, Steinemann, Doris, Stenmark-Askmalm, Marie, Stoppa-Lyonnet, Dominique, Swerdlow, Anthony, Szabo, Csilla I, Tamimi, Rulla, Tapper, William, Teixeira, Manuel R, Teo, Soo-Hwang, Terry, Mary B, Thomassen, Mads, Thompson, Deborah, Tihomirova, Laima, Toland, Amanda E, Tollenaar, Robert A E M, Tomlinson, Ian, Truong, Thérèse, Tsimiklis, Helen, Teulé, Alex, Tumino, Rosario, Tung, Nadine, Turnbull, Clare, Ursin, Giske, Van Deurzen, Carolien H M, Van Rensburg, Elizabeth J, Varon-Mateeva, Raymonda, Wang, Zhaoming, Wang-Gohrke, Shan, Weiderpass, Elisabete, Weitzel, Jeffrey N, Whittemore, Alice, Wildiers, Hans, Winqvist, Robert, Yang, Xiaohong R, Yannoukakos, Drakoulis, Yao, Song, Zamora, M Pilar, Zheng, Wei, Hall, Per, Kraft, Peter, Vachon, Celine, Slager, Susan, Chenevix-Trench, Georgia, Pharoah, Paul D P, Monteiro, Alvaro A N, Garcia-Closas, Montserrat, Easton, Douglas F, Antoniou, Antonis C.

Publikováno v: Couch, F. J. et al. Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer. Nat. Commun. 7:11375 doi: 10.1038/ncomms11375 (2016).

Externí odkaz: https://hdl.handle.net/10037/10393

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer.

Autor: Couch FJ; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA.; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Kuchenbaecker KB; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Michailidou K; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Mendoza-Fandino GA; Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA., Nord S; Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, N-0310 Oslo, Norway., Lilyquist J; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Olswold C; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Hallberg E; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Agata S; Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV-IRCCS, 20133 Padua, Italy., Ahsan H; Department of Health Studies, The University of Chicago, Chicago, Illinois 60637, USA.; Comprehensive Cancer Center, The University of Chicago, Chicago, Illinois 60637, USA.; Departments of Medicine and Human Genetics, The University of Chicago, Chicago, Illinois 60637, USA., Aittomäki K; Department of Clinical Genetics, Helsinki University Central Hospital, 00029 Helsinki, Finland., Ambrosone C; Department of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, New York 14263, USA., Andrulis IL; Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5.; Departments of Molecular Genetics and Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Canada M5B 1W8., Anton-Culver H; Department of Epidemiology, University of California Irvine, Irvine, California, 92697, USA., Arndt V; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Arun BK; University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Arver B; Department of Oncology, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Barile M; Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, 20141 Milan, Italy., Barkardottir RB; Department of Pathology, Landspitali University Hospital and University of Iceland School of Medicine, 101 Reykjavik, Iceland., Barrowdale D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Beckmann L; Institute for Quality and Efficiency in Health Care (IQWiG), 50670 Cologne, Germany., Beckmann MW; University Breast Center Franconia, Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, 91054 Erlangen, Germany., Benitez J; Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Centre (CNIO), 28029 Madrid, Spain.; Genotyping Unit (CeGen), Human Cancer Genetics Program, Spanish National Cancer Centre (CNIO), 28029 Madrid, Spain.; Biomedical Network on Rare Diseases (CIBERER), 28029 Madrid, Spain., Blank SV; NYU Women's Cancer Program, New York University School of Medicine, New York, New York 10016, USA., Blomqvist C; Department of Oncology, University of Helsinki and Helsinki University Central Hospital, FI-00029 Helsinki, Finland., Bogdanova NV; Department of Radiation Oncology, Hannover Medical School, 30625 Hannover, Germany., Bojesen SE; Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, 2730 Herlev, Denmark., Bolla MK; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Bonanni B; Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, 20141 Milan, Italy., Brauch H; Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, 70376 Stuttgart, Germany.; University of Tübingen 72074 Tübingen, Germany., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), 69120 Heidelberg, Germany., Burwinkel B; Department of Obstetrics and Gynecology, University of Heidelberg, 69120 Heidelberg, Germany., Buys SS; Department of Medicine, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City Utah 84112, USA., Caldes T; Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC, Madrid 28040, Spain., Caligo MA; Section of Genetic Oncology, Department of Laboratory Medicine, University and University Hospital of Pisa, I-56126 Pisa, Italy., Canzian F; Genomic Epidemiology Group, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Carpenter J; Australian Breast Cancer Tissue Bank, Westmead Millennium Institute, University of Sydney, Sydney, New South Wales 2145, Australia., Chang-Claude J; Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Chanock SJ; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20850, USA., Chung WK; Departments of Pediatrics and Medicine, Columbia University, New York, New York 10032, USA., Claes KB; Center for Medical Genetics, Ghent University, 9000 Ghent, Belgium., Cox A; Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield, Sheffield S10 2RX, UK., Cross SS; Academic Unit of Pathology, Department of Neuroscience, University of Sheffield, Sheffield S10 2HQ, UK., Cunningham JM; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, USA., Czene K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-17177 Stockholm, Sweden., Daly MB; Department of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA., Damiola F; INSERM U1052, CNRS UMR5286, Université Lyon, Centre de Recherche en Cancérologie de Lyon, 69373 Lyon, France., Darabi H; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-17177 Stockholm, Sweden., de la Hoya M; Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC, Madrid 28040, Spain., Devilee P; Department of Human Genetics and Department of Pathology, Leiden University Medical Center, Leiden 2333 ZC, The Netherlands., Diez O; Oncogenetics Group, University Hospital Vall d'Hebron, Vall d'Hebron Institute of Oncology (VHIO) and Universitat Autònoma de Barcelona, 08035 Barcelona, Spain., Ding YC; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California 91010, USA., Dolcetti R; Cancer Bioimmunotherapy Unit, CRO Aviano National Cancer Institute, 33081 Aviano , Italy., Domchek SM; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Pennsylvania 19104, USA., Dorfling CM; Department of Genetics, University of Pretoria, Pretoria 0007, South Africa., Dos-Santos-Silva I; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK., Dumont M; Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec and Laval University, Quebec City, Quebec, Canada G1V 4G2., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK., Eccles DM; Faculty of Medicine, University of Southampton, University Hospital Southampton, Southampton, Hampshire SO16 6YD, UK., Ehrencrona H; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala SE-751 85, Sweden.; Department of Clinical Genetics, Lund University Hospital, SE-22185 Lund, Sweden., Ekici AB; Institute of Human Genetics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, 91054 Erlangen, Germany.; Comprehensive Cancer Center -EMN, 91054 Erlangen, Germany., Eliassen H; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA., Ellis S; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Fasching PA; University Breast Center Franconia, Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, 91054 Erlangen, Germany., Figueroa J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20850, USA., Flesch-Janys D; Department of Cancer Epidemiology/Clinical Cancer Registry and Institute for Medical Biometrics and Epidemiology, University Clinic Hamburg-Eppendorf, 20246 Hamburg, Germany., Försti A; Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.; Center for Primary Health Care Research, Lund University, SE-221 00 Malmö, Sweden., Fostira F; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis, 15310 Athens, Greece., Foulkes WD; Program in Cancer Genetics, McGill University, Montreal, Quebec, Canada H3A 0G4., Friebel T; University of, Philadelphia, Pennsylvania 19104, USA., Friedman E; Susanne Levy Gertner Oncogenetics Unit, Sheba Medical Center, Tel-Hashomer 52621, Israel., Frost D; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Gabrielson M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-17177 Stockholm, Sweden., Gammon MD; Department of Epidemiology, University of, Chapel Hill, North Carolina 27599-7400, USA., Ganz PA; UCLA Schools of Medicine and Public Health, Division of Cancer Prevention and Control Research, Jonsson Comprehensive Cancer Center, Los Angeles, California 90095-6900, USA., Gapstur SM; Epidemiology Research Program, American Cancer Society, Atlanta, Georgia 30303, USA., Garber J; Cancer Risk and Prevention Clinic, Dana Farber Cancer Institute, Boston, Massachusetts 02215, USA., Gaudet MM; Epidemiology Research Program, American Cancer Society, Atlanta, Georgia 30303, USA., Gayther SA; Department of Biomedical Sciences, Cedars Sinai Medical Center, Los Angeles, California 90048, USA., Gerdes AM; Department of Clinical Genetics, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark., Ghoussaini M; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK., Giles GG; Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3010, Australia., Glendon G; Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5., Godwin AK; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, 66205, USA., Goldberg MS; Department of Medicine, McGill University, Montreal, Quebec, Canada H3G 2M1.; Division of Clinical Epidemiology, McGill University Health Centre, Royal Victoria Hospital, Montreal, Quebec, Canada H4A 3J1., Goldgar DE; Department of Dermatology, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah 84132, USA., González-Neira A; Human Genotyping-CEGEN Unit, Human Cancer Genetics Program, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain., Greene MH; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20850-9772, USA., Gronwald J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Guénel P; Inserm (National Institute of Health and Medical Research), CESP (Center for Research in Epidemiology and Population Health), U1018, Environmental Epidemiology of Cancer, 70-115 Villejuif, France., Gunter M; Department of of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, SW7 2AZ, UK., Haeberle L; University Breast Center Franconia, Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen-EMN, 91054 Erlangen, Germany., Haiman CA; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., Hamann U; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Hansen TV; Center for Genomic Medicine, Rigshospitalet, Copenhagen University Hospital, DK-2100 Copenhagen, Denmark., Hart S; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Healey S; Department of Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland 4029, Australia., Heikkinen T; Department of Obstetrics and Gynecology, University of Heidelberg, 69120 Heidelberg, Germany.; Helsinki University Central Hospital, FI-00029 Helsinki, Finland., Henderson BE; Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California 90033, USA., Herzog J; Clinical Cancer Genetics, for the City of Hope Clinical Cancer Genetics Community Research Network, Duarte, California 91010, USA., Hogervorst FB; Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam 1000 BE, The Netherlands., Hollestelle A; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam 3008 AE, The Netherlands., Hooning MJ; Department of Medical Oncology, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam 3008 AE, The Netherlands., Hoover RN; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Maryland 20850, USA., Hopper JL; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria 3010, Australia., Humphreys K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, SE-17177 Stockholm, Sweden., Hunter DJ; Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA., Huzarski T; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Imyanitov EN; N.N. Petrov Institute of Oncology, 197758 St Petersburg, Russia., Isaacs C; Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20007, USA., Jakubowska A; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., James P; Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Victoria 8006, Australia.; Department of Oncology, The University of Melbourne, Melbourne, Victoria 8006, Australia., Janavicius R; State Research Institute Centre for Innovative Medicine, LT-08661 Vilnius, Lithuania., Jensen UB; Department of Clinical Genetics, Aarhus University Hospital, 8200 Aarhus N, Denmark., John EM; Department of Epidemiology, Cancer Prevention Institute of California, Fremont, California 94538, USA., Jones M; Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton SM2 5NG, UK., Kabisch M; Molecular Genetics of Breast Cancer, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany., Kar S; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK., Karlan BY; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, 90048, USA., Khan S; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, FI-00029 Helsinki, Finland., Khaw KT; Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge CB1 8RN, UK., Kibriya MG; Department of Health Studies, The University of Chicago, Chicago, Illinois 60637, USA., Knight JA; Prosserman Centre for Health Research, Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5., Ko YD; Department of Internal Medicine, Evangelische Kliniken Bonn gGmbH, Johanniter Krankenhaus, 53113 Bonn, Germany., Konstantopoulou I; Molecular Diagnostics Laboratory, INRASTES, National Centre for Scientific Research 'Demokritos', Aghia Paraskevi Attikis, 15310 Athens, Greece., Kosma VM; School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, FI-70211 Kuopio, Finland., Kristensen V; Department of Genetics, Institute for Cancer Research, Oslo University Hospital, Radiumhospitalet, N-0310 Oslo, Norway., Kwong A; The Hong Kong Hereditary Breast Cancer Family Registry, Cancer Genetics Center, Hong Kong Sanatorium and Hospital, Hong Kong.; Department of Surgery, The University of Hong Kong, Hong Kong, China., Laitman Y; Susanne Levy Gertner Oncogenetics Unit, Sheba Medical Center, Tel-Hashomer 52621, Israel., Lambrechts D; Vesalius Research Center, VIB, 3000 Leuven, Belgium., Lazaro C; Molecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology, 08908 Barcelona, Spain., Lee E; Department of Preventive Medicine, University of Southern California, Los Angeles, California 90032, USA., Le Marchand L; Cancer Epidemiology Program, University of Cancer Center, Honolulu, Hawaii 96813, USA., Lester J; Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, 90048, USA., Lindblom A; Department of Molecular Medicine and Surgery, Karolinska Institutet, SE-17177 Stockholm, Sweden., Lindor N; Health Sciences Research, Mayo Clinic, Scotsdale, Arizona 85259, USA., Lindstrom S; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard School of Public Health, Boston, Massachusetts 02115, USA., Liu J; Human Genetics Division, Genome Institute of Singapore, Singapore 138672, Singapore., Long J; Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA., Lubinski J; Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland., Mai PL; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20850-9772, USA., Makalic E; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Victoria 3010, Australia., Malone KE; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.; Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, Washington 98195, USA., Mannermaa A; School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, University of Eastern Finland, FI-70211 Kuopio, Finland., Manoukian S; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), 20133 Milan, Italy., Margolin S; Department of Oncology, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Marme F; Department of Obstetrics and Gynecology, University of Heidelberg, 69120 Heidelberg, Germany., Martens JW; Department of Medical Oncology, Erasmus MC Cancer Institute, Rotterdam 3008 AE, The Netherlands., McGuffog L; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK., Meindl A; Department of Gynaecology and Obstetrics, Technical University of Munich, 81675 Munich, Germany., Miller A; NRG Oncology Statistics and Data Management Center, Roswell Park Cancer Institute, Buffalo, New York 14263, USA., Milne RL; Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Victoria 3010, Australia., Miron P; Department of Genomics and Genome Sciences, Case Western Reserve University Medical School, Cleveland, Ohio 44106, USA., Montagna M; Immunology and Molecular Oncology Unit, Istituto Oncologico Veneto IOV-IRCCS, 20133 Padua, Italy., Mazoyer S; INSERM U1052, CNRS UMR5286, Université Lyon, Centre de Recherche en Cancérologie de Lyon, 69373 Lyon, France., Mulligan AM; Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada M5B 1W8.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada M5B 1W8., Muranen TA; Department of Obstetrics and Gynecology, University of Heidelberg, 69120 Heidelberg, Germany.; Helsinki University Central Hospital, FI-00029 Helsinki, Finland., Nathanson KL; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Pennsylvania 19104, USA., Neuhausen SL; Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California 91010, USA., Nevanlinna H; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, FI-00029 Helsinki, Finland., Nordestgaard BG; Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, 2730 Herlev, Denmark., Nussbaum RL; Invitae Corporation, San Francisco, California 94107, USA., Offit K; Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA., Olah E; Department of Molecular Genetics, National Institute of Oncology, H-1122 Budapest, Hungary., Olopade OI; Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center, Chicago, Illinois 60637, USA., Olson JE; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota 55905, USA., Osorio A; Human Genetics Group, Human Cancer Genetics Program, Spanish National Cancer Centre (CNIO), 28029 Madrid, Spain., Park SK; Department of Preventive Medicine and Biomedical Science, Seoul National University College of Medicine and Cancer Research Institute, Seoul National University, 110-799 Seoul, Republic of Korea., Peeters PH; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht 3508 GA, The Netherlands.; MRC-PHE Centre for Environment and Health, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London SW7 2AZ, UK., Peissel B; Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), 20133 Milan, Italy., Peterlongo P; IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, 20133 Milan, Italy., Peto J; Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK., Phelan CM; Cancer Epidemiology Program, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, USA., Pilarski R; Divison of Human Genetics, Department of Internal Medicine, The Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA., Poppe B; Center for Medical Genetics, Ghent University, 9000 Ghent, Belgium., Pylkäs K; Laboratory of Cancer Genetics and Tumor Biology, Department of Clinical Chemistry and Biocenter Oulu, University of Oulu, NordLab Oulu/Oulu University Hospital, FI-90220 Oulu, Finland., Radice P; Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), 20133 Milan, Italy., Rahman N; Section of Cancer Genetics, Institute of Cancer Research, Sutton SM2 5NG, UK., Rantala J; Department of Clinical Genetics, Karolinska University Hospital, SE-17176 Stockholm, Sweden., Rappaport C; Department of Obstetrics and Gynecology, Comprehensive Cancer Center, Medical University of Vienna, A 1090 Vienna, Austria., Rennert G; Clalit National Israeli Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center and B. 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Publikováno v: Nature communications [Nat Commun] 2016 Apr 27; Vol. 7, pp. 11375. Date of Electronic Publication: 2016 Apr 27.