Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Lily Southcott"'
Autor:
Caterina F. Ramogida, Andrew K. H. Robertson, Una Jermilova, Chengcheng Zhang, Hua Yang, Peter Kunz, Jens Lassen, Ivica Bratanovic, Victoria Brown, Lily Southcott, Cristina Rodríguez-Rodríguez, Valery Radchenko, François Bénard, Chris Orvig, Paul Schaffer
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 4, Iss 1, Pp 1-20 (2019)
Abstract Background Actinium-225 (225Ac, t1/2 = 9.9 d) is a promising candidate radionuclide for use in targeted alpha therapy (TAT), though the currently limited global supply has hindered the development of a suitable Ac-chelating ligand and 225Ac-
Externí odkaz:
https://doaj.org/article/c0bdf4239e5f40f0b278e347743bcfe5
Autor:
Aidan Ingham, Luke Wharton, Tarek El Sayed, Lily Southcott, Brooke L. McNeil, Maria B. Ezhova, Brian O. Patrick, María de Guadalupe Jaraquemada-Peláez, Chris Orvig
Publikováno v:
Inorganic Chemistry. 61:9119-9137
Autor:
Celia Pena-Bonhome, Desiree Fiaccabrino, Tamara Rama, Daniel Fernández-Pavón, Lily Southcott, Zhengxing Zhang, Kuo-Shyan Lin, Andrés de Blas, Brian O. Patrick, Paul Schaffer, Chris Orvig, María de Guadalupe Jaraquemada-Peláez, Teresa Rodríguez-Blas
Publikováno v:
Inorganic Chemistry.
Autor:
Lily Southcott, Holger Stephan, Chris Orvig, María de Guadalupe Jaraquemada-Peláez, Brian O. Patrick, Lily Li
Publikováno v:
Inorganic Chemistry. 60:18082-18093
H4pypa is a nonadentate nonmacrocyclic chelator, which previously demonstrated high affinity for scandium-44, lutetium-177, and indium-111. Herein, we report the highly stable binary [Zr(pypa)] complex; the nonradioactive complex was synthesized and
Autor:
Hua Yang, Chris Orvig, Luke Wharton, Manja Kubeil, Xiaozhu Wang, Holger Stephan, Lily Southcott, Kristof Zarschler, María de Guadalupe Jaraquemada-Peláez, Neha Choudhary, Brian O. Patrick
Publikováno v:
Inorganic Chemistry. 60:12186-12196
A new versatile chelating ligand for intermediate size and softness radiometals [64Cu]Cu2+ and [111In]In3+, H2pyhox, was synthesized by introducing pyridine as a new donor moiety to complement 8-hydroxyquinoline on an ethylenediamine backbone. The co
Autor:
Milena Colovic, Hua Yang, Lily Southcott, Helen Merkens, Nadine Colpo, Francois Bénard, Paul Schaffer
Publikováno v:
Journal of Nuclear Medicine. :jnumed.122.265254
Autor:
Lily, Southcott, Luke, Wharton, Julie, Rousseau, Helen, Merkens, Hua, Yang, François, Bénard, Chris, Orvig
Publikováno v:
Journal of inorganic biochemistry. 235
A new, bifunctional chelating ligand for immuno-Positron Emission Tomography (PET) was designed, synthesized, and conjugated to Trastuzumab for a proof-of-concept study with
Autor:
Lily Southcott, Valery Radchenko, Hua Yang, Manja Kubeil, Xiaozhu Wang, María de Guadalupe Jaraquemada-Peláez, Luke Wharton, Holger Stephan, Chris Orvig
Publikováno v:
Dalton Transactions. 50:3874-3886
Advances in nuclear medicine depend on chelating ligands that form highly stable and kinetically inert complexes with relevant radiometal ions for use in diagnosis or therapy. A new potentially decadentate ligand, H5decaox, was synthesised to incorpo
Autor:
Manja Kubeil, Chris Orvig, Xiaozhu Wang, Hannah K Wagner, Holger Stephan, Thomas I. Kostelnik, Lily Southcott, María de Guadalupe Jaraquemada-Peláez
Publikováno v:
Inorganic Chemistry. 59:7238-7251
A phosphinate-bearing picolinic acid-based chelating ligand (H6dappa) was synthesized and characterized to assess its potential as a bifunctional chelator (BFC) for inorganic radiopharmaceuticals. Nuclear magnetic resonance (NMR) spectroscopy was emp
Autor:
Lily Southcott, Jennifer N. Whetter, Luke Wharton, Brian O. Patrick, Kristof Zarschler, Manja Kubeil, Holger Stephan, María de Guadalupe Jaraquemada-Peláez, Chris Orvig
Publikováno v:
Journal of Inorganic Biochemistry 231(2022), 111789
With the interest in radiometal-containing diagnostic and therapeutic pharmaceuticals burgeoning, appropriate ligands to coordinate completely and stably said radiometals is essential. Reported here are two novel, bis(amido)bis(oxinate)diamine ligand