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of 45
pro vyhledávání: '"Lily Shiue"'
Correction: Rapidly evolving protointrons in Saccharomyces genomes revealed by a hungry spliceosome.
Autor:
Jason Talkish, Haller Igel, Rhonda J Perriman, Lily Shiue, Sol Katzman, Elizabeth M Munding, Robert Shelansky, John Paul Donohue, Manuel Ares
Publikováno v:
PLoS Genetics, Vol 16, Iss 5, p e1008854 (2020)
[This corrects the article DOI: 10.1371/journal.pgen.1008249.].
Externí odkaz:
https://doaj.org/article/1a41684aba164dfa8f3e47fcb7b83adb
Autor:
Jason Talkish, Haller Igel, Rhonda J Perriman, Lily Shiue, Sol Katzman, Elizabeth M Munding, Robert Shelansky, John Paul Donohue, Manuel Ares
Publikováno v:
PLoS Genetics, Vol 15, Iss 8, p e1008249 (2019)
Introns are a prevalent feature of eukaryotic genomes, yet their origins and contributions to genome function and evolution remain mysterious. In budding yeast, repression of the highly transcribed intron-containing ribosomal protein genes (RPGs) glo
Externí odkaz:
https://doaj.org/article/bb1bc818d7cc45c9ab1f236047b04be5
Autor:
Katannya Kapeli, Gabriel A. Pratt, Anthony Q. Vu, Kasey R. Hutt, Fernando J. Martinez, Balaji Sundararaman, Ranjan Batra, Peter Freese, Nicole J. Lambert, Stephanie C. Huelga, Seung J. Chun, Tiffany Y. Liang, Jeremy Chang, John P. Donohue, Lily Shiue, Jiayu Zhang, Haining Zhu, Franca Cambi, Edward Kasarskis, Shawn Hoon, Manuel Ares Jr., Christopher B. Burge, John Ravits, Frank Rigo, Gene W. Yeo
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Abnormal functions of RNA-binding proteins TAF15, FUS and TDP43 are associated with amyotrophic lateral sclerosis. Here, Kapeli et al. characterize the RNA targets of TAF15 and identify points of convergence and divergence between the targets of TAF1
Externí odkaz:
https://doaj.org/article/d8f4356db05e4c6e9ae5ac8588f8d310
Autor:
Ruben G. de Bruin, Lily Shiue, Jurriën Prins, Hetty C. de Boer, Anjana Singh, W. Samuel Fagg, Janine M. van Gils, Jacques M. G. J. Duijs, Sol Katzman, Adriaan O. Kraaijeveld, Stefan Böhringer, Wai Y. Leung, Szymon M. Kielbasa, John P. Donahue, Patrick H.J. van der Zande, Rick Sijbom, Carla M. A. van Alem, Ilze Bot, Cees van Kooten, J. Wouter Jukema, Hilde Van Esch, Ton J. Rabelink, Hilal Kazan, Erik A. L. Biessen, Manuel Ares Jr., Anton Jan van Zonneveld, Eric P. van der Veer
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-20 (2016)
Post-transcriptional control of RNA is important in health and disease. Here, the authors show that the RNA-binding protein Quaking guides pre-mRNA splicing and transcript abundance during monocyte to macrophage differentiation, and that Quaking depl
Externí odkaz:
https://doaj.org/article/e34ae01b9e3449c1bdf812e5f403f63e
Autor:
Stephanie C. Huelga, Anthony Q. Vu, Justin D. Arnold, Tiffany Y. Liang, Patrick P. Liu, Bernice Y. Yan, John Paul Donohue, Lily Shiue, Shawn Hoon, Sydney Brenner, Manuel Ares, Jr., Gene W. Yeo
Publikováno v:
Cell Reports, Vol 1, Iss 2, Pp 167-178 (2012)
Understanding how RNA binding proteins control the splicing code is fundamental to human biology and disease. Here, we present a comprehensive study to elucidate how heterogeneous nuclear ribonucleoparticle (hnRNP) proteins, among the most abundant R
Externí odkaz:
https://doaj.org/article/5ea4085bf35e4d778e21aa158cbf14f8
Autor:
Mariaelena Pistoni, Lily Shiue, Melissa S Cline, Sergia Bortolanza, Maria Victoria Neguembor, Alexandros Xynos, Manuel Ares, Davide Gabellini
Publikováno v:
PLoS Genetics, Vol 9, Iss 1, p e1003186 (2013)
Facioscapulohumeral muscular dystrophy (FSHD) is a common muscle disease whose molecular pathogenesis remains largely unknown. Over-expression of FSHD region gene 1 (FRG1) in mice, frogs, and worms perturbs muscle development and causes FSHD-like phe
Externí odkaz:
https://doaj.org/article/32d6e9b875e04184a08c865a0ec7f0de
Publikováno v:
PLoS Computational Biology, Vol 1, Iss 4, p e39 (2005)
Splicing is an important process for regulation of gene expression in eukaryotes, and it has important functional links to other steps of gene expression. Two examples of these linkages include Ceg1, a component of the mRNA capping enzyme, and the ch
Externí odkaz:
https://doaj.org/article/04fec0e6363f4e27886f2419f91039fd
Growing evidence indicates that alternative or aberrant pre-mRNA splicing takes place during the development, progression, and metastasis of breast cancer. However, which splicing changes that might contribute directly to tumorigenesis or cancer prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8f7a8b1569a62e13bfb58114399c01
https://doi.org/10.1158/0008-5472.c.6495002
https://doi.org/10.1158/0008-5472.c.6495002
Supplementary Tables S1-S5 from Cell Type and Culture Condition–Dependent Alternative Splicing in Human Breast Cancer Cells Revealed by Splicing-Sensitive Microarrays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c106386c3a86a33c789cd30fb7bb78c
https://doi.org/10.1158/0008-5472.22366118.v1
https://doi.org/10.1158/0008-5472.22366118.v1
Supplementary Figure S1 from Cell Type and Culture Condition–Dependent Alternative Splicing in Human Breast Cancer Cells Revealed by Splicing-Sensitive Microarrays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d432ec59d29ff99f79d0b030918c992
https://doi.org/10.1158/0008-5472.22366121.v1
https://doi.org/10.1158/0008-5472.22366121.v1