Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lily Ramyar"'
Publikováno v:
Endocrine pathology. 1(4)
The effects of somatostatin or the somatostatin analog SMS 201–995 were studied on 4 densely granulated somatotroph adenomas and 4 sparsely granulated somatotroph adenomas in vitro. Release of growth hormone (GH) into culture media during incubatio
Autor:
Lily Ramyar, Bharati Bapat, Kara Semotiuk, Brian H Li, Soultana Tsitsikotas, Sheron Perera, Aaron Pollett
Publikováno v:
The Journal of Molecular Diagnostics. 12:757-764
Germline mutations in mismatch repair genes predispose patients to Lynch Syndrome and the majority of these mutations have been detected in two key genes, MLH1 and MSH2. In particular, about a third of the missense variants identified in MLH1 are of
Publikováno v:
The American Journal of Surgical Pathology. 24:1622-1626
Hyalinizing trabecular tumors of the thyroid are interesting but uncommon neoplasms. They have been classified as benign hyalinizing trabecular adenomas or malignant hyalinizing trabecular carcinomas. They share both epidemiologic and morphologic fea
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 85:878-882
Among thyroid neoplasms, Hurthle cell tumors (HCTs) have traditionally been a distinct diagnostic category. Hurthle cell adenomas are encapsulated follicular lesions with benign behavior. Hurthle cell carcinomas exhibit unequivocal capsular and/or va
Autor:
D. Rologis, Eleni Thodou, Spyros Tzanis, George Kontogeorgos, H. Salla, A. Levedis, Lily Ramyar, Sylvia L. Asa, G. Piaditis, E. Kyrodimou, N. Anagnostopoulos, E. Vamvassakis
Publikováno v:
Scopus-Elsevier
The purpose of this study was to detect in vitro growth hormone (GH) and prolactin (PRL) secretion from adenomas clinically associated with GH or PRL hypersecretion. The reverse hemolytic plaque assay (RHPA) was applied in order to reveal possible di
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 80:878-884
Basic fibroblast growth factor (bFGF) is a potent mitogenic and angiogenic factor that is known to regulate GH, PRL, and TSH secretion. Sequences within a bFGF gene family member have been detected in transforming DNA samples derived from human PRL-s
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 80:534-539
Growth factors induce cell proliferation and are implicated in the multistep process of tumorigenesis. Transforming growth factor-alpha (TGF alpha), a peptide that binds to the epidermal growth factor receptor, is expressed by carcinomas and normal t
Autor:
Zi Cheng, Lily Ramyar, Sylvia L. Asa, William Singer, Kalman Kovacs, Paul J. Muller, H. S. Smyth
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 74:1128-1134
Human pituitary null cell adenomas and oncocytomas are not associated with evidence of excess hormone secretion in vivo; their cellular derivation has not been clarified by morphologic investigation. In this study we examined 41 null cell adenomas an
Autor:
Lily Ramyar, Aaron Pollett, Bharati Bapat, Melyssa Aronson, Marsha Speevak, Sheron Perera, Steven Gallinger, Angie Mitri
Publikováno v:
Journal of human genetics. 55(1)
Mutations in mismatch repair genes lead to Lynch Syndrome, the most common form of inherited colorectal cancer. In this report, we describe a novel complex germline mutation c.[1601_1661+92dup; 1591_1611del] of the mismatch repair gene, MSH2. This mu
Autor:
Elizabeth Spriggs, Terri Berk, Angela Mitri, Cheryl R. Greenberg, B. N. Chodirker, Lily Ramyar, Hong Cheng, Jack H. Jung, George S. Charames, Bharati Bapat, Patricia Bocangel
Publikováno v:
Human genetics. 124(5)
Familial adenomatous polyposis (FAP) is an autosomal dominant syndrome caused by the inheritance of germline mutations in the APC tumour suppressor gene. The vast majority of these are nonsense and frameshift mutations resulting in a truncated protei