Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Lily Jun-Shen Huang"'
Autor:
Liming Yu, Lin Xu, Haiyan Chu, Jun Peng, Anastasia Sacharidou, Hsi-hsien Hsieh, Ada Weinstock, Sohaib Khan, Liqian Ma, José Gabriel Barcia Durán, Jeffrey McDonald, Erik R. Nelson, Sunghee Park, Donald P. McDonnell, Kathryn J. Moore, Lily Jun-shen Huang, Edward A. Fisher, Chieko Mineo, Linzhang Huang, Philip W. Shaul
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Hypercholesterolemia and vascular inflammation are key interconnected contributors to the pathogenesis of atherosclerosis. How hypercholesterolemia initiates vascular inflammation is poorly understood. Here we show in male mice that hypercho
Externí odkaz:
https://doaj.org/article/acdb55d979ff40c6a879b2daab171d43
Autor:
Li-shu Zhang, Xunlei Kang, Jianming Lu, Yuannyu Zhang, Xiaofeng Wu, Guojin Wu, Junke Zheng, Rubina Tuladhar, Heping Shi, Qiaoling Wang, Lorraine Morlock, Huiyu Yao, Lily Jun-shen Huang, Pascal Maire, James Kim, Noelle Williams, Jian Xu, Chuo Chen, Cheng Cheng Zhang, Lawrence Lum
Publikováno v:
EBioMedicine, Vol 39, Iss , Pp 145-158 (2019)
Background: Chromosomal translocation-induced expression of the chromatin modifying oncofusion protein MLL-AF9 promotes acute myelocytic leukemia (AML). Whereas WNT/β-catenin signaling has previously been shown to support MLL-AF9-driven leukemogenes
Externí odkaz:
https://doaj.org/article/73d06b7f64ea44e7a85caf179ec3fdad
Publikováno v:
Haematologica, Vol 105, Iss 4 (2020)
Externí odkaz:
https://doaj.org/article/3bc280dba3004cf9a455971d83e2558d
Autor:
Xiuli Liu, Aishwarya A. Gogate, Melodi Tastemel, Venkat S. Malladi, Huiyu Yao, Kim Nguyen, Lily Jun-Shen Huang, Xiaoying Bai
Publikováno v:
Blood Advances, Vol 1, Iss 18, Pp 1358-1367 (2017)
Abstract: The negative elongation factor (NELF) complex is a metazoan-specific factor essential for establishing transcription pausing. Although NELF has been implicated in cell-fate regulation, the cellular regulation of NELF and its intrinsic role
Externí odkaz:
https://doaj.org/article/5896cb85a68d4dcc99f3ca330bbac786
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
Type I and II cytokine receptors are cell surface sensors that bind cytokines in the extracellular environment and initiate intracellular signaling to control processes such as hematopoiesis, immune function, and cellular growth and development. One
Externí odkaz:
https://doaj.org/article/9af391f55bc14570817d6c865c1ad3b8
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 4, p e1003022 (2013)
The Janus Kinase 2 (JAK2) plays essential roles in transmitting signals from multiple cytokine receptors, and constitutive activation of JAK2 results in hematopoietic disorders and oncogenesis. JAK2 kinase activity is negatively regulated by its pseu
Externí odkaz:
https://doaj.org/article/f1e01e537402430cbfda52ce21bb4408
Autor:
Hsi-Hsien Hsieh, Huiyu Yao, Yue Ma, Yuannyu Zhang, Xue Xiao, Helen Stephens, Naureen Wajahat, Stephen S. Chung, Lin Xu, Jian Xu, Raajit K. Rampal, Lily Jun-shen Huang
Publikováno v:
Blood. 140:2371-2384
We found that in regenerative erythropoiesis, the erythroid progenitor landscape is reshaped, and a previously undescribed progenitor population with colony-forming unit-erythroid (CFU-E) activity (stress CFU-E [sCFU-E]) is expanded markedly to resto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd77add9490713ce8fccffcc5e98453b
https://doi.org/10.1182/blood.2022016741
https://doi.org/10.1182/blood.2022016741
Autor:
Hsi-Hsien Hsieh, Huiyu Yao, Yue Ma, Yuannyu Zhang, Xue Xiao, Helen Stephens, Stephen S. Chung, Lin Xu, Jian Xu, Raajit K. Rampal, Lily Jun-shen Huang
We find that in regenerative erythropoiesis, the erythroid progenitor landscape is reshaped, and a previously undescribed progenitor population with CFU-E activity (stress CFU-E/sCFU-E) is markedly expanded to restore the erythron. sCFU-E are targets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f63ba58e9a26bf03d444217bf66cd033
https://doi.org/10.1101/2022.06.27.497649
https://doi.org/10.1101/2022.06.27.497649
Autor:
Huiyu Yao, Junke Zheng, Li-shu Zhang, Lawrence G. Lum, Cheng Cheng Zhang, Lily Jun Shen Huang, Jianming Lu, Heping Shi, Noelle S. Williams, Pascal Maire, James Kim, Rubina Tuladhar, Lorraine Morlock, Chuo Chen, Xiaofeng Wu, Jian Xu, Xunlei Kang, Qiaoling Wang, Yuannyu Zhang, Guojin Wu
Publikováno v:
EBioMedicine
Background Chromosomal translocation-induced expression of the chromatin modifying oncofusion protein MLL-AF9 promotes acute myelocytic leukemia (AML). Whereas WNT/β-catenin signaling has previously been shown to support MLL-AF9-driven leukemogenesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f06527c59cdc183ec9e77f7aa29ac8ad
https://doi.org/10.1016/j.ebiom.2018.11.039
https://doi.org/10.1016/j.ebiom.2018.11.039
Autor:
Zhenya Hong, Jane E. Craig, Taosheng Chen, Lily Jun Shen Huang, Wei Zhuang, Gamze B. Bulut, Sadie Miki Sakurada, Jonathan Low, Malia B. Potts, Jamshid Temirov, Joseph N. Miller, Raju R. Rayavarapu, Shondra M. Pruett-Miller
Publikováno v:
Cell Death Discovery
Cell Death Discovery, Vol 6, Iss 1, Pp 1-13 (2020)
Cell Death Discovery, Vol 6, Iss 1, Pp 1-13 (2020)
Mitochondria are vital organelles that coordinate cellular energy homeostasis and have important roles in cell death. Therefore, the removal of damaged or excessive mitochondria is critical for maintaining proper cellular function. The PINK1-Parkin p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e35506dd5c5cc74f18ba5897b121cc5
https://pubmed.ncbi.nlm.nih.gov/33101709
https://pubmed.ncbi.nlm.nih.gov/33101709