Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Lily I, Cheng"'
Autor:
Emmanuelle Gras, Trang T. T. Vu, Nhu T. Q. Nguyen, Vuvi G. Tran, Yanjie Mao, Nguyen D. Tran, Nam H. Mai, Oliver X. Dong, David H. Jung, Natalia L. P. P. Iorio, Helvecio C. C. Povoa, Marcos Gabriel Pinheiro, Fabio Aguiar-Alves, William J. Weiss, Bo Zheng, Lily I. Cheng, Charles K. Stover, Bret R. Sellman, Antonio DiGiandomenico, Laure Gibault, Florent Valour, Binh An Diep
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
BackgroundNew drugs targeting antimicrobial resistant pathogens, including Pseudomonas aeruginosa, have been challenging to evaluate in clinical trials, particularly for the non-ventilated hospital-acquired pneumonia and ventilator-associated pneumon
Externí odkaz:
https://doaj.org/article/711b678c4c3e47ab9251fd8fcab51201
Autor:
Jacqueline A. Wright, Cassandra Bazile, Emily S. Clark, Gianluca Carlesso, Justin Boucher, Eden Kleiman, Tamer Mahmoud, Lily I. Cheng, Darlah M. López-Rodríguez, Anne B. Satterthwaite, Norman H. Altman, Eric L. Greidinger, Wasif N. Khan
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
While apoptosis plays a role in B-cell self-tolerance, its significance in preventing autoimmunity remains unclear. Here, we report that dysregulated B cell apoptosis leads to delayed onset autoimmune phenotype in mice. Our longitudinal studies revea
Externí odkaz:
https://doaj.org/article/eab5bbc02d4a4b57baacd503e0b3f214
Autor:
Sean K. Maynard, Jason D. Marshall, Randall S. MacGill, Li Yu, Jennifer A. Cann, Lily I. Cheng, Michael P. McCarthy, Corinne Cayatte, Scott H. Robbins
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Despite considerable efforts at developing therapeutic vaccines for cancer, clinical translation of preclinical successes has been challenging, largely due to the difficulty of inducing strong and sustained cytotoxic T lymphocyte
Externí odkaz:
https://doaj.org/article/5d056bfa987f45eb836be09f7b6ba10b
Autor:
Ami Patel, Antonio DiGiandomenico, Ashley E. Keller, Trevor R. F. Smith, Daniel H. Park, Stephanie Ramos, Katherine Schultheis, Sarah T. C. Elliott, Janess Mendoza, Kate E. Broderick, Megan C. Wise, Jian Yan, Jingjing Jiang, Seleeke Flingai, Amir S. Khan, Kar Muthumani, Laurent Humeau, Lily I. Cheng, Leslie Wachter-Rosati, C. Kendall Stover, Niranjan Y. Sardesai, David B. Weiner
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
DNA-delivered monoclonal antibodies (DMAbs) can be produced by muscle cells in vivo, potentially allowing prevention or treatment of infectious diseases. Here, the authors show that two DMAbs targeting Pseudomonas aeruginosa proteins confer protectio
Externí odkaz:
https://doaj.org/article/5cc6f71f1078455d97d037b4f8457a6b
Autor:
Rakesh Kumar, Amaya Gascó Hernández, Natalia Ceaicovscaia, Maozhen Gong, Delphine Lissa, Karl Fraser, Nicholas M. Durham, Emily C. Jennings, Sonia Agrawal, Lily I. Cheng, Mark T. Esser, Jean Boyer, Marcelo Bonomi, Mercedes Porosnicu, Missak Haigentz, Tanguy Y. Seiwert, Ammar Sukari, Alain Algazi, Nabil F. Saba, Charu Aggarwal
Supplementary Table S1. Representativeness of Study Participants Supplementary Table S2. Disease response as assessed by RECIST v1.1 by PD-L1 tumor cell expression (response-evaluable population). Supplementary Table S3. Disease response as assessed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad24f29865515292b62ff30864060b0
https://doi.org/10.1158/1078-0432.22490335.v1
https://doi.org/10.1158/1078-0432.22490335.v1
Autor:
Rakesh Kumar, Amaya Gascó Hernández, Natalia Ceaicovscaia, Maozhen Gong, Delphine Lissa, Karl Fraser, Nicholas M. Durham, Emily C. Jennings, Sonia Agrawal, Lily I. Cheng, Mark T. Esser, Jean Boyer, Marcelo Bonomi, Mercedes Porosnicu, Missak Haigentz, Tanguy Y. Seiwert, Ammar Sukari, Alain Algazi, Nabil F. Saba, Charu Aggarwal
Supplementary Figure S1. Patient disposition. Supplementary Figure S2. Association of PD-L1 expression and HPV status with best antitumor response. Supplementary Figure S3. Kaplan-Meier distribution curves for (A) PFS and (B) OS in the as-treated pop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9a25141bab23dd8f6083cb326173c6
https://doi.org/10.1158/1078-0432.22490338.v1
https://doi.org/10.1158/1078-0432.22490338.v1
Autor:
Rakesh Kumar, Amaya Gascó Hernández, Natalia Ceaicovscaia, Maozhen Gong, Delphine Lissa, Karl Fraser, Nicholas M. Durham, Emily C. Jennings, Sonia Agrawal, Lily I. Cheng, Mark T. Esser, Jean Boyer, Marcelo Bonomi, Mercedes Porosnicu, Missak Haigentz, Tanguy Y. Seiwert, Ammar Sukari, Alain Algazi, Nabil F. Saba, Charu Aggarwal
Purpose:Tumoral programmed cell death ligand-1 (PD-L1) expression is common in human papillomavirus (HPV)–associated head and neck squamous cell carcinoma (HNSCC). We assessed whether a DNA vaccine targeting HPV-16/18 E6/E7 with IL12 adjuvant (MEDI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::491114b0233b1825295289b6616a2d15
https://doi.org/10.1158/1078-0432.c.6533137.v1
https://doi.org/10.1158/1078-0432.c.6533137.v1
Autor:
Charu Aggarwal, Nabil F. Saba, Alain Algazi, Ammar Sukari, Tanguy Y. Seiwert, Missak Haigentz, Mercedes Porosnicu, Marcelo Bonomi, Jean Boyer, Mark T. Esser, Lily I. Cheng, Sonia Agrawal, Emily C. Jennings, Nicholas M. Durham, Karl Fraser, Delphine Lissa, Maozhen Gong, Natalia Ceaicovscaia, Amaya Gascó Hernández, Rakesh Kumar
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 29, iss 3
Purpose: Tumoral programmed cell death ligand-1 (PD-L1) expression is common in human papillomavirus (HPV)–associated head and neck squamous cell carcinoma (HNSCC). We assessed whether a DNA vaccine targeting HPV-16/18 E6/E7 with IL12 adjuvant (MED
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30d7dd3b4d6278c10d8b9948e138f327
https://escholarship.org/uc/item/3wz58697
https://escholarship.org/uc/item/3wz58697
Autor:
Fábio Aguiar-Alves, Hoan N. Le, Vuvi G. Tran, Emmanuelle Gras, Trang T. T. Vu, Oliver X. Dong, Josiane Silva Quetz, Lily I. Cheng, Li Yu, Bret R. Sellman, Charles K. Stover, Antonio DiGiandomenico, Binh An Diep
Publikováno v:
Antimicrobial agents and chemotherapy. 66(2)
Ventilator-associated pneumonia is an important clinical manifestation of the nosocomial pathogen Pseudomonas aeruginosa. We characterized the correlates of protection with MEDI3902, a bispecific human IgG1 monoclonal antibody that targets the P. aer
Autor:
Nola J. Parsons, Tertius A. Gous, Michael R. Cranfield, Lily I. Cheng, Albert Schultz, Elizabeth Horne, Robert P. Last, François Lampen, Katrin Ludynia, Barry Bousfield, Venessa Strauss, Michael A. Peirce, Ralph E. T. Vanstreels
Publikováno v:
Polar Biology. 41:79-86
The King Penguin (Aptenodytes patagonicus) is a pelagic seabird that breeds on Subantarctic islands and is considered a rare vagrant in South Africa. From 2001 to 2017, six King Penguins were rescued along the South African coast and admitted into re