Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Lily C. Hsu"'
Publikováno v:
Biochemical Journal. 339:387-395
Mammalian class I aldehyde dehydrogenase (ALDH1) has been implicated as a retinal dehydrogenase in the biosynthesis of retinoic acid, a modulator of gene expression and cell differentiation. As the first step towards studying the regulation of ALDH1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::178e112b8c0c631f86e02a0e7f8cb418
https://doi.org/10.1042/bj3390387
https://doi.org/10.1042/bj3390387
Publikováno v:
Scopus-Elsevier
Twelve aldehyde dehydrogenase (ALDH) genes have been identified in humans. These genes, located on different chromosomes, encode a group of enzymes which oxidizes varieties of aliphatic and aromatic aldehydes. Metabolic disorders and clinical problem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3671253d60f789096afb6daf95f1fe4
https://doi.org/10.1046/j.1432-1327.1998.2510549.x
https://doi.org/10.1046/j.1432-1327.1998.2510549.x
Publikováno v:
Gene. 189:89-94
The structure of two human aldehyde dehydrogenase genes, ALDH7 and ALDH8, have been determined. The ALDH7 gene spans about 20 kb of the human genomic DNA and is composed of 9 coding exons. The ALDH8 gene is over 10 kb in length and consists of at lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f75fbfb1ed2c47cca0ab5ca58e7c7cb0
https://doi.org/10.1016/s0378-1119(96)00839-6
https://doi.org/10.1016/s0378-1119(96)00839-6
Publikováno v:
Journal of Biological Chemistry. 270:17521-17527
Human cytosolic aldehyde dehydrogenase 1 (ALDH1) plays a role in the biosynthesis of retinoic acid that is a modulator for gene expression and cell differentiation. Northern blot analysis showed that liver tissue, pancreas tissue, hepatoma cells, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12dae782122ffc9dfac1fe03d399d2fc
https://doi.org/10.1074/jbc.270.29.17521
https://doi.org/10.1074/jbc.270.29.17521
Publikováno v:
Journal of Biological Chemistry. 267:3030-3037
An aldehyde dehydrogenase isozyme, ALDH3, which is strongly expressed in the stomach, may play a role in the oxidation of toxic aldehydes. Using reverse genetic approach, we cloned and characterized the cDNA and the gene for the ALDH3. The full lengt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39b68d214b68339ee10c5410f2d8246d
https://doi.org/10.1016/s0021-9258(19)50690-1
https://doi.org/10.1016/s0021-9258(19)50690-1
Autor:
Wen-Chung Chang, Lily C. Hsu
Publikováno v:
Journal of Biological Chemistry. 266:12257-12265
We cloned a new functional ALDH gene (ALDHx) from a human genomic library in cosmid pWE-15 by screening with a 29-nucleotide probe partially matched to a conserved region of the ALDH1 and ALDH2 genes. The new ALDHx gene does not contain introns in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd349bbd3652ae89475df01930667056
https://doi.org/10.1016/s0021-9258(18)98890-3
https://doi.org/10.1016/s0021-9258(18)98890-3
Publikováno v:
Biochimica et biophysica acta. 1492(1)
Retinaldehyde dehydrogenase (RALDH) isozymes catalyze the formation of an essential developmental modulator, retinoic acid. We determined the structural organization of mouse type-2 Raldh2 by isolation of overlapping genomic DNA clones from a phage l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb29f97f2712350c6ebced58aab8cfb
https://pubmed.ncbi.nlm.nih.gov/10858567
https://pubmed.ncbi.nlm.nih.gov/10858567
Publikováno v:
Scopus-Elsevier
Whether or not nuclear introns predate the divergence of bacteria and eukaryotes is the central argument between the proponents of the “introns-early” and “introns-late” theories. In this study we compared the goodness-of-fit of each theory w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d2b864327317d0f928583c15e4757a6
https://pubmed.ncbi.nlm.nih.gov/9192649
https://pubmed.ncbi.nlm.nih.gov/9192649
Autor:
Lily C. Hsu, Wen-Chung Chang
Publikováno v:
Gene. 174(2)
The human aldehyde dehydrogenase gene ( ALDH ) family is characterized by two major conserved DNA sequences encoding residues which are possibly involved in the catalytic function and the maintenance of the functional conformation of the ALDH enzyme.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a2ce2a5018b3c4f7e400abef722915d
https://pubmed.ncbi.nlm.nih.gov/8890755
https://pubmed.ncbi.nlm.nih.gov/8890755
Publikováno v:
Genomics. 34(3)
The cDNA and the gene (ALDH9) for a human aldehyde dehydrogenase isozyme, which has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes, were cloned and characterized. The cDNA has an open reading frame of 1479 bp enco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d191ea9b9235b76c78848787b0af7d
https://pubmed.ncbi.nlm.nih.gov/8786138
https://pubmed.ncbi.nlm.nih.gov/8786138