Zobrazeno 1 - 10 of 41 pro vyhledávání: '"Lily C. Chao"'
2
Akademický článek
The macrophage LBP gene is an LXR target that promotes macrophage survival and atherosclerosis
Autor: Tamer Sallam, Ayaka Ito, Xin Rong, Jason Kim, Caroline van Stijn, Brian T. Chamberlain, Michael E. Jung, Lily C. Chao, Marius Jones, Thomas Gilliland, XiaoHui Wu, Grace L. Su, Rajendra K. Tangirala, Peter Tontonoz, Cynthia Hong
Publikováno v: Journal of Lipid Research, Vol 55, Iss 6, Pp 1120-1130 (2014)
The liver X receptors (LXRs) are members of the nuclear receptor superfamily that regulate sterol metabolism and inflammation. We sought to identify previously unknown genes regulated by LXRs in macrophages and to determine their contribution to athe
Externí odkaz: https://doaj.org/article/afa01ecac86245dc937e46ebaf3d70ed
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3
Akademický článek
Bone marrow NR4A expression is not a dominant factor in the development of atherosclerosis or macrophage polarization in mice[S]
Autor: Lily C. Chao, Erin Soto, Cynthia Hong, Ayaka Ito, Liming Pei, Ajay Chawla, Orla M. Conneely, Rajendra K. Tangirala, Ronald M. Evans, Peter Tontonoz
Publikováno v: Journal of Lipid Research, Vol 54, Iss 3, Pp 806-815 (2013)
The formation of the atherosclerotic lesion is a complex process influenced by an array of inflammatory and lipid metabolism pathways. We previously demonstrated that NR4A nuclear receptors are highly induced in macrophages in response to inflammator
Externí odkaz: https://doaj.org/article/29b91d7455394aef8be275635f72a7f6
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4
Akademický článek
Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization[S]
Autor: Lily C. Chao, Kevin Wroblewski, Olga R. Ilkayeva, Robert D. Stevens, James Bain, Gretchen A. Meyer, Simon Schenk, Leonel Martinez, Laurent Vergnes, Vihang A. Narkar, Brian G. Drew, Cynthia Hong, Rima Boyadjian, Andrea L. Hevener, Ronald M. Evans, Karen Reue, Melissa J. Spencer, Christopher B. Newgard, Peter Tontonoz
Publikováno v: Journal of Lipid Research, Vol 53, Iss 12, Pp 2610-2619 (2012)
Mitochondrial dysfunction has been implicated in the pathogenesis of type 2 diabetes. Identifying novel regulators of mitochondrial bioenergetics will broaden our understanding of regulatory checkpoints that coordinate complex metabolic pathways. We
Externí odkaz: https://doaj.org/article/200f6c56942e45de9e72f398c1dfc174
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5
Akademický článek
Liver X receptors are regulators of adipocyte gene expression but not differentiation
Autor: Sarah Hummasti, Bryan A. Laffitte, Michael A. Watson, Cristin Galardi, Lily C. Chao, Lakshman Ramamurthy, John T. Moore, Peter Tontonoz
Publikováno v: Journal of Lipid Research, Vol 45, Iss 4, Pp 616-625 (2004)
The liver X receptors α and β (LXRα and LXRβ) have been shown to play important roles in lipid homeostasis in liver and macrophages, however, their function in adipose tissue is not well defined. Both LXRs are highly expressed in fat, and the exp
Externí odkaz: https://doaj.org/article/1dc8ad0596f8411fa603b1f399007441
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6
Youth-onset type 2 diabetes mellitus: an urgent challenge
Autor: Petter, Bjornstad, Lily C, Chao, Melanie, Cree-Green, Allison B, Dart, Malcolm, King, Helen C, Looker, Dianna J, Magliano, Kristen J, Nadeau, Orit, Pinhas-Hamiel, Amy S, Shah, Daniel H, van Raalte, Meda E, Pavkov, Robert G, Nelson
Publikováno v: Nature reviews. Nephrology.
The incidence and prevalence of youth-onset type 2 diabetes mellitus (T2DM) and its complications are increasing worldwide. Youth-onset T2DM has been reported in all racial and ethnic groups, but Indigenous peoples and people of colour are disproport
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1fa3c93a6f82fa3cddf1c929e933c943
https://pubmed.ncbi.nlm.nih.gov/36316388
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8
Once-Weekly Dulaglutide for the Treatment of Youths with Type 2 Diabetes
Autor: Silva A, Arslanian, Tamara, Hannon, Philip, Zeitler, Lily C, Chao, Claudia, Boucher-Berry, Margarita, Barrientos-Pérez, Elise, Bismuth, Sergio, Dib, Jang Ik, Cho, David, Cox, Chandan, Saha
Publikováno v: The New England journal of medicine. 387(5)
The incidence of type 2 diabetes mellitus is increasing among youths. Once-weekly treatment with dulaglutide, a glucagon-like peptide-1 receptor agonist, may have efficacy with regard to glycemic control in youths with type 2 diabetes.In a double-bli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a9346c0a8d5a7650b861922af71cd2
https://pubmed.ncbi.nlm.nih.gov/36260804
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10
Spike in Diabetic Ketoacidosis Rates in Pediatric Type 2 Diabetes During the COVID-19 Pandemic
Autor: Alaina P. Vidmar, Lily C. Chao, Senta Georgia
Publikováno v: Diabetes Care
OBJECTIVE The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) on the incidence of new-onset type 2 diabetes and diabetic ketoacidosis (DKA) is unclear. It is unknown whether the coincidence of DKA noted in adult patients with ty
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237b87cdb43a33ef617992c5ca94cd60
http://europepmc.org/articles/PMC8247527
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