Nutrient-deprivation autophagy factor-1 (NAF-1): biochemical properties of a novel cellular target for anti-diabetic drugs.

Autor: Sagi Tamir, John A Zuris, Lily Agranat, Colin H Lipper, Andrea R Conlan, Dorit Michaeli, Yael Harir, Mark L Paddock, Ron Mittler, Zvi Ioav Cabantchik, Patricia A Jennings, Rachel Nechushtai

Publikováno v: PLoS ONE, Vol 8, Iss 5, p e61202 (2013)

Nutrient-deprivation autophagy factor-1 (NAF-1) (synonyms: Cisd2, Eris, Miner1, and Noxp70) is a [2Fe-2S] cluster protein immune-detected both in endoplasmic reticulum (ER) and mitochondrial outer membrane. It was implicated in human pathology (Wolfr

Externí odkaz: https://doaj.org/article/784e2a071f1348ef8f98f442fc369770

Differential DNA methylation of vocal and facial anatomy genes in modern humans

Autor: Mona Dvir-Ginzberg, Malka Nissim-Rafinia, Tal Shahar, Iddi Lipende, Ronald E. Bontrop, David Reich, Lily Agranat-Tamir, Liran Carmel, Heng Li, Ottmar Kullmer, Yonatan Lahav, Genevieve Housman, Eran Meshorer, Maria A. Nieves-Colón, Olivia Cheronet, Marina Faerman, Richard M. Gronostajski, David Gokhman, Leonid Kandel, Mario Novak, Julio M. Vidal, Carles Lalueza-Fox, Raquel García-Pérez, Anne C. Stone, Esther Lizano, Songül Alpaslan-Roodenberg, Benjamin Yakir, Ellen E. Quillen, Hongcang Gu, Alexander Meissner, Deus Mjungu, Ron Pinhasi, Gerhard W. Weber, Swapan Mallick, Jason M. Osinski, María E. Prada, Manuel Ferrando-Bernal, Tomas Marques-Bonet, Pere Gelabert, Meir Liebergall, Ivanela Kondova

Publikováno v: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
Nature Communications, 11(1). Nature Publishing Group
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
Recercat: Dipósit de la Recerca de Catalunya
Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)

Changes in potential regulatory elements are thought to be key drivers of phenotypic divergence. However, identifying changes to regulatory elements that underlie human-specific traits has proven very challenging. Here, we use 63 reconstructed and ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0157e05b1b124af13af9f888d04587
https://ddd.uab.cat/record/234397

The Genomic History of the Bronze Age Southern Levant

Autor: Liran Carmel, Janet Monge, Naama Yahalom-Mack, Nadav Mishol, Kristin Stewardson, Vered Eshed, Jonas Oppenheimer, Shlomit Bechar, Tzilla Eshel, Ann Marie Lawson, Francesca Candilio, Israel Finkelstein, Shay Tzur, Shamam Waldman, Megan Michel, Benjamin Yakir, David Gokhman, Shai Carmi, Swapan Mallick, David Reich, Yigal Erel, Olivia Cheronet, Rachel Kalisher, Douglas J. Kennett, Marina Faerman, Matthew Mah, Yehuda Govrin, Mario A.S. Martin, Lily Agranat-Tamir, Nicole Adamski, Denise Keating, Ron Pinhasi, Beatriz Gamarra, Mario Novak, Nadin Rohland

Publikováno v: Cell

We report genome-wide DNA data for 73 individuals from five archaeological sites across the Bronze and Iron Ages Southern Levant. These individuals, who share the ‘‘Canaanite’’ material culture, can be modeled as descending from two sources:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::585573d1cb5ab259b11917d57c7e6768
https://doi.org/10.1016/j.cell.2020.04.024

Dual function of C/D box small nucleolar RNAs in rRNA modification and alternative pre-mRNA splicing

Autor: Marina Falaleeva, Zaneta Matuszek, Amadís Pagès, Ruth Sperling, Yuval Nevo, Stefan Stamm, Lily Agranat-Tamir, Eduardo Eyras, Konstantin V. Korotkov, Sana Hidmi

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 113(12)

Significance C/D box small nucleolar RNAs (SNORDs) are abundant, short, nucleoli-residing, noncoding RNAs that guide the methyltransferase fibrillarin to perform 2′- O -methylation of target RNAs. We identified 29 SNORDs present in a fibrillarin-co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45108f5e566d53ff4954507edfac8cd8
https://pubmed.ncbi.nlm.nih.gov/26957605

Structure-function analysis of NEET proteins uncovers their role as key regulators of iron and ROS homeostasis in health and disease

Autor: Dorit Michaeli, Merav Darash-Yahana-Baram, Faruck Morcos, Colin H. Lipper, Sagi Tamir, Ioav Cabantchik, Jason T. Stofleth, Yang Sung Sohn, Mark L. Paddock, José N. Onuchic, Ron Mittler, Lily Agranat, Patricia A. Jennings, Sarah H. Holt, Rachel Nechushtai

Publikováno v: Biochimica et biophysica acta. 1853(6)

A novel family of 2Fe–2S proteins, the NEET family, was discovered during the last decade in numerous organisms, including archea, bacteria, algae, plant and human; suggesting an evolutionary-conserved function, potentially mediated by their CDGSH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e19b52f91e3f5f3a3f590e60e4170d
https://pubmed.ncbi.nlm.nih.gov/25448035