High-Dose Intravenous Methylprednisolone for Hantavirus Cardiopulmonary Syndrome in Chile: A Double-Blind, Randomized Controlled Clinical Trial

Autor: Pablo A. Vial, Francisca Valdivieso, Marcela Ferres, Raul Riquelme, M. Luisa Rioseco, Mario Calvo, Constanza Castillo, Ricardo Díaz, Luis Scholz, Analia Cuiza, Edith Belmar, Carla Hernandez, Jessica Martinez, Sang-Joon Lee, Gregory J. Mertz, Juan Abarca, Vinko Tomicic, M. Eugenia Aracena, Ana Maria Rehbein, Soledad Velásquez, Victoria Lavin, Felipe Garrido, Paula Godoy, Constanza Martinez, Juan Carlos Chamorro, Jorge Contreras, Jury Hernandez, Marcelo Pino, Paola Villegas, Viviana Zapata, Marisol León, Ivonne Vega, Irisol Otarola, Carlos Ortega, Elizabeth Daube, Doris Huecha, Alda Neira, Ines Ruiz, M. Antonieta Nuñez, Luz Monsalve, Henriette Chabouty, Lorena Riquelme, Samia Palma, Raul Bustos, Ruben Miranda, Jovita Mardones, Nora Hernandez, Yasna Betancur, Ligia Sanhueza, Jaime Inostroza, Solange Donoso, Maritza Navarrete, Lily Acuña, Paulina Manriquez, Fabiola Castillo, Paola Unzueta, Teresa Aguilera, Carola Osorio, Veronica Yobanolo, Jorge Mardones, Sandra Aranda, Soledad Carvajal, Moisés Sandoval, Soraya Daza, Felipe Vargas, Violeta Diaz, Mauricio Riquelme, Miriam Muñoz, Andrea Carriel, Paola Lanino, Susana Hernandez, Patricia Schumacher, Lia Yañez, Claudia Marco, Mildred Ehrenfeld, Iris Delgado, Susana Rios, Cecilia Vial, Edward Bedrick

Background. Andes virus (ANDV)–related hantavirus cardiopulmonary syndrome (HCPS) has a 35% case fatality rate in Chile and no specific treatment. In an immunomodulatory approach, we evaluated the efficacy of intravenous methylprednisolone for HCPS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56afd430cbe3c4effcd5b1577634b3f4
https://europepmc.org/articles/PMC3765009/