Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lilusi Ma"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2023)
Coacervates are droplets formed by liquid‒liquid phase separation. An increasing number of studies have reported that coacervates play an important role in living cells, such as in the generation of membraneless organelles, and peptides contribute
Externí odkaz:
https://doaj.org/article/c87dc8986fa24d0baa7ac99df14af23e
Publikováno v:
Royal Society Open Science, Vol 6, Iss 6 (2019)
Misfolding and abnormal aggregation of β-amyloid peptide is associated with the onset and progress of Alzheimer's disease (AD). Therefore, modulating β-amyloid aggregation is critical for the treatment of AD. Herein, we studied the regulatory effec
Externí odkaz:
https://doaj.org/article/5fd7ce511e144026a4f44d82baee4880
Autor:
Mengting Chen, Yuchen Lin, Xiaocui Fang, Yanlian Yang, Chen Wang, Mingpeng Liu, Lilusi Ma, Jingyi Liu, Mei Jiang
Publikováno v:
Journal of Materials Chemistry B. 9:4895-4905
A novel delivery system for cisplatin was constructed based on electrostatics-mediated assemblies of gold nanoclusters and PEGylated cationic peptide (cisplatin@GC-pKs). Encapsulated cisplatin in the as-formed micelle like assemblies was observed to
Autor:
Kaiyue Zhang, Haiyan Xu, Yanlian Yang, Yuchen Lin, Xiaocui Fang, Shilin Xu, Yangyang Ge, Chen Wang, Lilusi Ma, Qing You
Publikováno v:
Materials Advances. 1:3483-3495
Delivery and accumulation of therapeutic drugs into neoplastic cells distant from tumor vessels is a major challenge for antitumor therapy. Herein, we introduced a de novo peptide, p12 (QGSRRRNTVDDWISRRRALC), to conjugate onto the surface of doxorubi
Autor:
Mei Jiang, Xiaocui Fang, Lilusi Ma, Mingpeng Liu, Mengting Chen, Jingyi Liu, Yanlian Yang, Chen Wang
Publikováno v:
International Journal of Pharmaceutics. 622:121894
EZH2 is an overexpressed nuclear protein associated with relatively poor survival and chemoresistance in lung cancer. In this study, a nucleus-targeting peptide antagonist EIP103 capable of penetrating cell membrane and nuclear envelope was identifie
Autor:
Kaiyue Zhang, Jian Liu, Yanlian Yang, Xiaocui Fang, Lilusi Ma, Haiyan Xu, Mei Jiang, Chen Wang
Publikováno v:
International journal of pharmaceutics. 594
Lymph node metastases in cancer patients are associated with high aggressiveness, poor prognosis, and short survival time. The chemokine receptor 4 (CXCR4)/stroma derived factor 1α (CXCL12) biological axis plays a critical role in the spread of canc
Autor:
Changliang Liu, Hongyang Duan, Zijian Zhao, Wenzhe Li, Lilusi Ma, Xiaocui Fang, Chen Wang, Yanlian Yang
Publikováno v:
RSC Advances. 8:39948-39956
The metastasis of breast cancer is one of the main factors resulting in the high fatality of patients. Although many antagonists have been developed to inhibit the metastasis of breast cancer, their practical application has been limited because of t
Publikováno v:
Materials Science and Engineering: C. 79:237-244
Liposomes are one of the most widely studied drug carriers due to their relative biocompatibility, lack of immune system stimulation, ability to be cell specific, and serve as a protective drug carrier. Due to several physicochemical properties such
Publikováno v:
Royal Society Open Science, Vol 6, Iss 6 (2019)
Royal Society Open Science
Royal Society Open Science
Misfolding and abnormal aggregation of β-amyloid peptide is associated with the onset and progress of Alzheimer's disease (AD). Therefore, modulating β-amyloid aggregation is critical for the treatment of AD. Herein, we studied the regulatory effec
Autor:
Doudou Yan, Tao Wen, Yangyang Ge, Jian Liu, Min Wang, Haiyan Xu, Haiyan Xing, Chen Wang, Yanlian Yang, Jianxiang Wang, Jie Meng, Lilusi Ma, Xiaocui Fang, Hui Wei, Shilin Xu
Publikováno v:
Small. 16:2001890
Acute myeloid leukemia (AML) is the most common adult acute leukemia with very low survival rate due to drug resistance and high relapse rate. The C-X-C chemokine receptor 4 (CXCR4) is highly expressed by AML cells, actively mediating chemoresistance